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A Case of Pulmonary Benign Metastasizing Leiomyoma Occurring after Uterine Myomectomy A Case of Pulmonary Benign Metastasizing Leiomyoma Occurring after Uterine Myomectomy Fukushima, Yasutsugu Hirata, Hiroyuki Maezawa, Reika Yoshida, Naruo Hayashi, Yumeko Arai, Ryo Fukushima, Fumiya Sugiyama, Kumiya Kurasawa, Kazuhiro Ishii, Yoshiki Fukuda, Takeshi uterine myoma pulmonary benign metastasizing leiomyoma video associated thoracoscopic surgery Benign metastasizing leiomyoma (BML) is a very rare disease, and although it was reported as early as1939 to result from metastasis of benign uterine myoma to the lungs and lymph nodes, its pathology remainsobscure. Here, we describe a case of pulmonary BML occurring after uterine myomectomy in a42-year-old woman. She presented with a 2-week history of dry cough on exertion. Chest radiography andcomputed tomography( CT) revealed bilateral multiple nodular lesions. The patient had a history of uterinemyoma and previously underwent myomectomy. For definitive diagnosis, lung biopsy was performed byvideo associated thoracoscopic surgery. Histopathologic examination of biopsy specimens revealed pulmonaryBML occurring after uterine myomectomy. For treatment of the pulmonary BML, gonadotropin-releasinghormone was initially administered, and 1 month later the patient underwent complete hysterectomyand bilateral salpingo-oophorectomy. Chest CT 6 months after surgery showed that the size and number oflung multiple nodular lesions did not increase compared with those before surgery. In future studies, we aimto investigate a larger number of pulmonary BML cases, as well as establish specific treatments and investigatethe prognosis of the disease.Abbreviations:BML:benign metastasizing leiomyomaSS:Sjögren's syndromeCT:computed tomographyH&E:hematoxylin and eosinVATS:video associated thoracoscopic surgeryCA:carbohydrate antigenIg:immunoguloblina SMA:a smooth muscle actin Case Report 2010-07-25 eng journal article https://dmu.repo.nii.ac.jp/records/849 AA00629581 03855023 Dokkyo journal of medical sciences 37 2 119 124 https://dmu.repo.nii.ac.jp/record/849/files/KJ00006378199.pdf application/pdf 238.0 kB 2017-05-24