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oai:dmu.repo.nii.ac.jp:00000338 2023-06-20T16:28:22Z 81:34

Effects of Tobacco Smoking on Frontal Lobe Function in Normal Healthy Volunteer Effects of Tobacco Smoking on Frontal Lobe Function in Normal Healthy Volunteer Matsuda, Naoto Yuki, Tsumugi Akiyama, Kazufumi Hirata, Koichi nicotine Wisconsin Card Sorting Test (WCST) frontal lobe tobacco smoking To evaluate the efficacy of tobacco smoking on working memory of healthy normal volunteer, Computer-based-revised Keio type Wisconsin Card Sorting Test (WCST) was administered and analyzed. Thirteen normal healthy nonsmokers and 10 normal healthy smokers had WCST, however, for smoker group WCST was administered immediately after tobacco smoking (1mg of nicotine and 12mg of tar). As the results, smoker group showed higher score in both Number of response card until the first category achieved (NUCA) and Perseverative errors of Nelson (PEN) (P<0.05). These results indicate that smokers have difficulty in changing and maintaining mental set, which means decrease in flexibility and adaptability of attention. These data suggest that tobacco smoking may have acute effect on working memory of brain. 原著 Original 2005-07-25 eng journal article https://dmu.repo.nii.ac.jp/records/338 AA00629581 03855023 Dokkyo journal of medical sciences 32 2 81 83 https://dmu.repo.nii.ac.jp/record/338/files/KJ00004439017.pdf application/pdf 270.6 kB 2017-05-24