@article{oai:dmu.repo.nii.ac.jp:00001002, author = {Ishibashi, Shota and Kamisasanuki, Toshiro and Morita, Kimio and Takebayashi, Kohzo and Aso, Yoshimasa and Ikegami, Keiichi and Inukai, Toshihiko}, issue = {1}, journal = {Dokkyo journal of medical sciences}, month = {Mar}, note = {We experienced a case of water intoxication due to excessive water ingestion that was complicated by the syndrome of inappropriate secretion of antidiuretic hormone (SIADH). A 60-year-old Japanese woman with nervous depression drank too much lemon tea within several hours, vomited ten times, and developed disturbed consciousness and dysarthria. Her plasma arginine vasopressin (AVP) concentration was not inhibited,although her plasma osmolality was low. Nausea and/or stress may stimulate AVP secretion regardless of the hypo-osmolality. We believe that dilatation of her stomach due to excessive liquid ingestion and cerebral edema due to hypo-osmolality brought on her nausea. Stress induced by a psychiatric problem and/or admission to a hospital may also stimulate AVP secretion by the central nervous system. Treatingnausea and stress may help reduce AVP secretion and resolve hyponatremia., Case Report}, pages = {77--80}, title = {A case in which water intoxication due to excessive water ingestion did not inhibit the secretion of arginine vasopressin}, volume = {39}, year = {2012} }