@article{oai:dmu.repo.nii.ac.jp:00000111, author = {Sugamata, Yuichi and Zeng, Xiao-Hui and Hozumi, Akinori and Tanaka, Hideaki and Hirata, Koichi}, issue = {1}, journal = {Dokkyo journal of medical sciences}, month = {Mar}, note = {The Go and NoGo conditions of the Continuous Performance Test (CPT) of event-related brain potentials (ERPs) represent the execution and inhibition of a participating motor control. The present study examined this cognitive response control in 20 healthy normal ageings when the subjects perform a visual CPT paradigm. A conventional 2-tones auditory paradigm was also used to elicit P3. The Global Field Power (GFP) was employed for an ERP component analysis. The new modified Wisconsin Card Sorting Test (WCST) was used to evaluate frontal lobe function, and Mini-Mental State Examination (MMSE) was used to exclude subjects with clinical intellective decline. P3 amplitude elicited by the NoGo condition significantly increased and the scalp location of its centroids was more anteriory distributed than in the Go condition. There was no difference in P3 latency to be found between Go and NoGo conditions. These results suggest that NoGo P3 may be a potential neurophysiological marker of cognitive response control. It is suitable to evaluate the capability of execution or inhibition in a prepared motor response., Original}, pages = {1--8}, title = {Cognitive Responses Control in Normal Ageing : Evidence from a Go/NoGo Task of Event-related Potentials}, volume = {30}, year = {2003} }