| Item type |
[ELS]学術雑誌論文 / Journal Article(1) |
| 公開日 |
2017-05-24 |
| タイトル |
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タイトル |
Longitudinal Changes in Quantitative EEG and Event- related Potentials in Healthy Elderly VolunTFFrs : A 4-year Follow-up Study |
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言語 |
en |
| 言語 |
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|
言語 |
eng |
| キーワード |
|
|
言語 |
en |
|
主題 |
normal aging |
| キーワード |
|
|
言語 |
en |
|
主題 |
ERP |
| キーワード |
|
|
言語 |
en |
|
主題 |
P300 |
| キーワード |
|
|
言語 |
en |
|
主題 |
quantitative EEG |
| キーワード |
|
|
言語 |
en |
|
主題 |
cognitive decline |
| 資源タイプ |
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資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
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資源タイプ |
journal article |
| 雑誌書誌ID |
|
|
収録物識別子 |
AA00629581 |
| 論文名よみ |
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タイトル |
Longitudinal Changes in Quantitative EEG and Event- related Potentials in Healthy Elderly VolunTFFrs : A 4-year Follow-up Study |
| 著者 |
Mori, Azuma
Nakano, Takashi
Asahi, Kimihiko
Akiyama, Kazufumi
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| 著者所属(英) |
|
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|
en |
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Department of Psychiatry, Dokkyo University School of Medicine |
| 著者所属(英) |
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en |
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Department of Psychiatry, Dokkyo University School of Medicine |
| 著者所属(英) |
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|
en |
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Department of Psychiatry, Dokkyo University School of Medicine |
| 著者所属(英) |
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en |
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Department of Psychiatry, Dokkyo University School of Medicine |
| 記事種別(英) |
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内容記述タイプ |
Other |
|
内容記述 |
Original |
| 抄録(英) |
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内容記述タイプ |
Other |
|
内容記述 |
Age-related changes of cognitive brain function are reflected by neurophysiological measurements such as quantitative electroencephalograms (EEG) and event -related potentials (ERP). However, longitudinal changes in these neurophysiological parameters in healthy elderly individuals have remained largely unreported. In the present study, quantitative EEG and ERP were measured prospectively twice, at an interval of 4 years, in 21 physically and cognitively healthy geriatric volunteers (age at first session, 66.3 ± 2.6 years). EEG data collected from 18 electrode sites on the cranial surface according to the 10-20 International System were used for quantitative analysis of waveform recognition for 1 mm under resting, awake, eyes-closed conditions. ERPs were elicited using an auditory oddball paradigm. With each subject, we compared EEG and ERP data obtained at the 2 sessions. The 4-year follow-up of quantitative BEG revealed a significant increase in the incidence of Qθ1 band waves and a significant decrease in the incidence of α2 band waves at nearly all sites. Although no changes in P300 amplitudes were observed, P300 latencies were significantly increased at the 2^<nd> session at all sites, with mean prolongation of 4.7 ± 0.7 ms/year. These results are consistent with those of previous cross-sectional studies, and provide the first prospective demonstration of subtle slowing of cognitive processes in normal elderly subjects. |
| 書誌情報 |
Dokkyo journal of medical sciences
巻 30,
号 1,
p. 23-28,
発行日 2003-03-25
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| ISSN |
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収録物識別子タイプ |
ISSN |
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収録物識別子 |
03855023 |
KJ00000010445.pdf (630.6 kB)
