@article{oai:dmu.repo.nii.ac.jp:00001150, author = {川合, 覚 and 石原, 優吾 and 笹井, 貴子 and 高橋, 史成 and 桐木, 雅史 and 林, 尚子 and 山崎, 浩 and 平石, 秀幸 and 千種, 雄一 and Kawai, Satoru and Ishihara, Yugo and Sasai, Takako and Takahashi, Fuminari and Kirinoki, Masashi and Kato-Hayashi, Naoko and Yamasaki, Hiroshi and Hiraishi, Hideyuki and Chigusa, Yuichi}, issue = {3}, journal = {Dokkyo journal of medical sciences}, month = {Oct}, note = {埼玉県在住の男性・64 歳.2012 年11 月初旬,近医で日本海裂頭条虫症の診断を受け,駆虫目的で本院消化器内科を紹介受診.外来で駆虫治療したところ,全長約250 cm の白色紐状で,全体的に肉厚感のある虫体を排出した.虫体は形態学的特徴より日本海裂頭条虫ではなく,クジラ複殖門条虫が強く疑われたため,遺伝子解析を行った.PCR によって増幅されたcytochrome c oxidase subunit 1 遺伝子(cox1)の全長塩基配列を解析したところ,既知のクジラ複殖門条虫の塩基配列と99%の相同性を示したことから,本症例はクジラ複殖門条虫症と確定した.該当患者は,便に白色紐状物が混入する2〜3 か月前に,生シラスを生食しており,これが感染源となった可能性が高いと考えられた., We have reported a case of infection with whale tapeworm,Diplogonoporus balaenopterae, in Dokkyo MedicalUniversity Hospital. The patient, a 64-year-old Japanesemale, living in Saitama Prefecture was admitted to our hospitalon Nov. 1st 2012, owing to pieces of tapeworm beingdischarged. He was treated with Biltricide® (20 mg/kg)and Magcorol P®( 100 g) in the hospital and he expelled atapeworm about 250 cm, in length along with the scolex afterabout 2 hours of treatment. Based on the morphologicalfeatures of the strobila and the scolex we strongly suspectedthat the tapeworm belongs to the genus Diplogonoporus.To identify the species of the discharged tapeworm, thecomplete cox1 gene was amplified by PCR and the nucleotidesequence was analyzed. The sequence showed 99 %homology against those from D. balaenopterae. From theseresults the patient was diagnosed as a diplogonoporiasiscaused by D. balaenopterae, whale tapeworm. We could notfind any proglottides of tapeworm nor eggs in stools whenwe performed follow up medical examinations three monthsafter treatment. Therefore it can be concluded that the patientwas cured of this disease. In most cases the infectionsource of the whale tapeworm to humans is reported ascoming from marine fish such as sardines and bonitos. Thepatient had frequently consumed various kinds of raw marinefish, and we suspect that the infection source can beattributed to eating raw whitebait., 症例報告, Case Report}, pages = {189--192}, title = {生シラスの生食による感染が疑われたクジラ複殖門条虫症の1 例}, volume = {40}, year = {2013}, yomi = {カワイ, サトル and イシハラ, ユウゴ and ササイ, タカコ and タカハシ, フミナリ and キリノキ, マサシ and ハヤシ, ナオコ and ヤマザキ, ヒロシ and ヒライシ, ヒデユキ and チグサ, ユウイチ} }