@article{oai:dmu.repo.nii.ac.jp:00001177,
 author = {矢崎, 美和 and 池田, 知史 and 藤井, 宏一 and 石川, 和由 and Yazaki, Miwa and Ikeda, Tomohito and Fujii, Koichi and Ishikawa, Kazuyoshi},
 issue = {1},
 journal = {Dokkyo journal of medical sciences},
 month = {Mar},
 note = {プロポフォール(PF)を用いた全静脈麻酔での,手術終了時のレミフェンタニル(RF)の持続投与量が精神運動機能(PMF)の回復に及ぼす影響について調べた.【方法】対象は副鼻腔手術が予定されたASAリスクI の患者55 人であった.麻酔維持は,PF を効果部位濃度3 m g/ml に固定し,RF をbisptectral index 値が50～60 になるよう用量調節,持続投与した.そして,手術終了から30 分毎にTrieger dot test を用いてPMFを評価し,結んだ線から逸脱した点の数(NDM),逸脱した点から線までの最大距離(MDDM)を記録した.【結果】手術終了時のRF の持続投与量は0.22±0.10 m g/kg/分であった.NDM とMDDM の値は,それぞれ手術終了後120 分間,90 分間にわたって麻酔前値に比較して有意に増加していた.しかし,何れの時間においても,手術終了時のRF の持続投与量とNDM とMDDM の値に相関関係は認めなかった.【結語】手術終了時のRF の持続投与量がPMF の回復に及ぼす影響は少なく,PF とRF を用いた全静脈麻酔では手術終了までRF による十分な鎮痛が可能であることが示唆された., The purpose of this study was to evaluate the correlation between recovery of psychomotor function and dose of remifentanil at the end of anesthesia in total intravenous anesthesia (TIVA) with propofol. Fifty five patients, who were scheduled for the sinus surgery under general anesthesia, were enrolled into this study. Anesthesia was induced and maintained with continuous infusion of propofol and remifentanil. Infusion of propofol was controlled using target control infusion pump (3 m g/mL at the effect site concentration). Infusion of remifentanil was adjusted by bispectral index (from 50 to 60). Psychomotor function, as measured by the Trieger dot test, was evaluated before anesthesia and 30 to 180 min after the end of TIVA. The number of dots missed (NDM) was significantly increased until 120 min after the end of TIVA, compared to the baseline vale. There was no significant correlation between value of NDM and dose of remifentanil at the end of TIVA during the study. The maximum distance of dots missed (MDDM) was significantly increased until 60 min after the end of TIVA, compared to the baseline value. There was no significant correlation between value of MDDM and dose of remifentanil at the end of TIVA during the study. Our results suggest that adequate dose of remifentanil can be administered until the end of surgery without delay of recovery of psychomotor functionin in TIVA with propofol and remifentanil., 原著},
 pages = {95--102},
 title = {手術終了時のレミフェンタニルの持続投与量が精神運動機能の回復に及ぼす影響について},
 volume = {41},
 year = {2014},
 yomi = {ヤザキ, ミワ and イケダ, トモヒト and フジイ, コウイチ and イシカワ, カズヨシ}
}