{"created":"2023-06-20T14:25:03.648837+00:00","id":123,"links":{},"metadata":{"_buckets":{"deposit":"b2cd64f1-a02c-41b5-b443-9ee67bfca386"},"_deposit":{"created_by":3,"id":"123","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"123"},"status":"published"},"_oai":{"id":"oai:dmu.repo.nii.ac.jp:00000123","sets":["81:25"]},"author_link":["369","370","368","367"],"item_2_biblio_info_12":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2003-03-25","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1","bibliographicPageEnd":"96","bibliographicPageStart":"93","bibliographicVolumeNumber":"30","bibliographic_titles":[{"bibliographic_title":"Dokkyo journal of medical sciences"}]}]},"item_2_description_11":{"attribute_name":"抄録(英)","attribute_value_mlt":[{"subitem_description":"We administered recombinant growth hormone (rGH) to a girl with systemic lupus erythematosus (SLE) complicated by steroid-induced growth failure and GH deficiency. However, the rGH therapy, which she underwent for 14 months, was not effective. The patient was diagnosed as SLE when she was 4 years and 10 months old, and her height before undergoing prednisolone was -1.0 SD score (SDS). She was treated with prednisolone (0.4-0.5 mg/kg/day) for a prolonged period. She was referred to us at 9 years of age because of persistent proteinuria that had begun when she was 7 years and 8 months old. We performed a renal biopsy (WHO SLE IIIA type) and noticed steroid-induced growth failure (-4.2 SDS), delay of bone maturation (5 years of age) and a low response to GH in the arginine and clonizine-loading test. We prescribed rGH therapy (0.175 mg/kg/week) and attempted to decrease prednisolone by administering cyclosporin A or mizolibine. However, prednisolone could not be decreased to less than 0.35 mg/kg/day for a long period. GH therapy for 14 months increased her height by only 2.8 cm (-4.4 SDS). The observations made in this SLE patient are consistent with those of Rivkees et al., who reported that when the prednisolone dose is greater than 0.35 mg/kg/day, rGH therapy does not increase the linear growth rate.","subitem_description_type":"Other"}]},"item_2_description_8":{"attribute_name":"記事種別(日)","attribute_value_mlt":[{"subitem_description":"症例報告","subitem_description_type":"Other"}]},"item_2_description_9":{"attribute_name":"記事種別(英)","attribute_value_mlt":[{"subitem_description":"Case Report","subitem_description_type":"Other"}]},"item_2_source_id_1":{"attribute_name":"雑誌書誌ID","attribute_value_mlt":[{"subitem_source_identifier":"AA00629581"}]},"item_2_source_id_19":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"03855023","subitem_source_identifier_type":"ISSN"}]},"item_2_text_7":{"attribute_name":"著者所属(英)","attribute_value_mlt":[{"subitem_text_language":"en","subitem_text_value":"Division of Endocrinology, Department of Pediatrics, Dokkyo University School of Medicine"},{"subitem_text_language":"en","subitem_text_value":"Division of Endocrinology, Department of Pediatrics, Dokkyo University School of Medicine"},{"subitem_text_language":"en","subitem_text_value":"Division of Endocrinology, Department of Pediatrics, Dokkyo University School of Medicine"},{"subitem_text_language":"en","subitem_text_value":"Division of Endocrinology, Department of Pediatrics, Dokkyo University School of Medicine"}]},"item_2_title_3":{"attribute_name":"論文名よみ","attribute_value_mlt":[{"subitem_title":"Failure of Growth Hormone Therapy in a Girl with Growth Hormone Deficiency and Steroid-induced Growth Failure Caused by Prednisolone Administration"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Kano, Kenichi","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Nishikura, Kiyoshi","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Yamada, Yumi","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Arisaka, Osamu","creatorNameLang":"en"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2017-05-24"}],"displaytype":"detail","filename":"KJ00000010454.pdf","filesize":[{"value":"339.5 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"KJ00000010454.pdf","url":"https://dmu.repo.nii.ac.jp/record/123/files/KJ00000010454.pdf"},"version_id":"de6be8b8-0507-48ed-aae8-4a4dfde22f6a"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"glucocorticoids","subitem_subject_language":"en"},{"subitem_subject":"growth hormone deficiency","subitem_subject_language":"en"},{"subitem_subject":"growth hormone therapy","subitem_subject_language":"en"},{"subitem_subject":"lupus nephritis short stature","subitem_subject_language":"en"},{"subitem_subject":"steroid-induced growth failure","subitem_subject_language":"en"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Failure of Growth Hormone Therapy in a Girl with Growth Hormone Deficiency and Steroid-induced Growth Failure Caused by Prednisolone Administration","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Failure of Growth Hormone Therapy in a Girl with Growth Hormone Deficiency and Steroid-induced Growth Failure Caused by Prednisolone Administration","subitem_title_language":"en"}]},"item_type_id":"2","owner":"3","path":["25"],"pubdate":{"attribute_name":"公開日","attribute_value":"2017-05-24"},"publish_date":"2017-05-24","publish_status":"0","recid":"123","relation_version_is_last":true,"title":["Failure of Growth Hormone Therapy in a Girl with Growth Hormone Deficiency and Steroid-induced Growth Failure Caused by Prednisolone Administration"],"weko_creator_id":"3","weko_shared_id":3},"updated":"2023-06-20T16:22:42.815894+00:00"}