{"created":"2023-06-20T14:26:01.172455+00:00","id":1263,"links":{},"metadata":{"_buckets":{"deposit":"3cfd1fa6-6138-4f23-bb82-09c95fd49cef"},"_deposit":{"created_by":3,"id":"1263","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"1263"},"status":"published"},"_oai":{"id":"oai:dmu.repo.nii.ac.jp:00001263","sets":["81:74"]},"author_link":["6245","6238","6240","6241","6243","6242","6239","6244"],"item_2_biblio_info_12":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2015-07-25","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"2","bibliographicPageEnd":"70","bibliographicPageStart":"63","bibliographicVolumeNumber":"42","bibliographic_titles":[{"bibliographic_title":"Dokkyo journal of medical sciences"}]}]},"item_2_description_10":{"attribute_name":"抄録(日)","attribute_value_mlt":[{"subitem_description":"B型肝炎ウィルス(hepatitis B virus:HBV)感染の防御は医療関連感染防止対策として重要である.当医科大学学生のB型肝炎(HB)ワクチン接種成績および1年後までのHBs抗体価の推移を観察し,HBワクチンの有用性について検討した.対象は2012年4月に入学した当医科大学の医学部学生・看護学部学生・附属看護専門学校学生とし,HBワクチン接種1シリーズ終了後,1年後まで経過観察できた277名(男性75名,女性202名)とした.ワクチン接種1シリーズの終了後および1年後のHBs抗体陽性者(率)はそれぞれ,医学部学生が99/101名(98.0%)→80/99名(80.8%),看護学部学生が92/94名(97.9%)→78/92名(84.8%),附属看護専門学校学生が82/82名(100%)→65/82名(79.3%)であり,全学生では273/277名(98.6%)→223/273名(81.7%)で,1年の経過観察でHBs抗体が陰性化した学生は約17%にみられた.また,ワクチン接種1シリーズ終了後のHBs抗体陽転者について,1年後までの抗体価の推移をみると,抗体持続陽性者は抗体陰性化者と比較して,ワクチン接種1シリーズ終了後の抗体価は医学部学生・看護学部学生・附属看護専門学校学生とも約5倍高く有意に高値であった(それぞれP<0.001,P=0.001,P=0.002).HBワクチンを接種してHBs抗体が陽転化し,経過中に抗体が陰性化した学生は,感染のリスクが高い環境にあり,HBワクチンの追加接種は今後検討が必要であると考えられる.","subitem_description_type":"Other"}]},"item_2_description_11":{"attribute_name":"抄録(英)","attribute_value_mlt":[{"subitem_description":"It is important to identify and immunize susceptible students who have clinical practice to prevent and control hospital infections. The immunogenicity of hepatitis B(HB) vaccination was evaluated among 277 students at DokkyoMedical University. Seroconversion to antibody to HB surface antigen (anti-HBs) was 98.6 % in all vaccinated students after vaccination and 98.0 % in medical students, 97.9 % in nursing students and 100 % in nursing school students. During a 1 year follw-up after vaccination, anti-HBs (+)was 81.7 % in all vaccinated students and 80.8 %, 84.8 % and 79.3 %, respectively. Anti-HBs levels were higher in female than in male,but not significant. At a 1 year period after vaccinatin, anti-HBs levels were undetectable in 16.9 % in all vaccinated students and in 17.2 %, 13.1 % and 20.7 %, respectively.In our findings, higher anti-HBs levels in all vaccinated students were protect of immunity. Therefore higher anti-HBs levels may be a indicator of protective immunity. In conclusion, our findings suggest that one or more booster immunizations may be needed in going seronegative status of anti-HBs by at least several years following student's immunization.","subitem_description_type":"Other"}]},"item_2_description_8":{"attribute_name":"記事種別(日)","attribute_value_mlt":[{"subitem_description":"原著","subitem_description_type":"Other"}]},"item_2_source_id_1":{"attribute_name":"雑誌書誌ID","attribute_value_mlt":[{"subitem_source_identifier":"AA00629581"}]},"item_2_source_id_19":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"03855023","subitem_source_identifier_type":"ISSN"}]},"item_2_text_6":{"attribute_name":"著者所属(日)","attribute_value_mlt":[{"subitem_text_value":"獨協医科大学病院 健康管理科"},{"subitem_text_value":"獨協医科大学病院 健康管理科"},{"subitem_text_value":"獨協医科大学病院 健康管理科"},{"subitem_text_value":"獨協医科大学病院 健康管理科:獨協医科大学 保健センター"}]},"item_2_text_7":{"attribute_name":"著者所属(英)","attribute_value_mlt":[{"subitem_text_language":"en","subitem_text_value":"Department Of Health Care, Dokkyo Medical University Hospital"},{"subitem_text_language":"en","subitem_text_value":"Department Of Health Care, Dokkyo Medical University Hospital"},{"subitem_text_language":"en","subitem_text_value":"Department Of Health Care, Dokkyo Medical University Hospital"},{"subitem_text_language":"en","subitem_text_value":"Department Of Health Care, Dokkyo Medical University Hospital:Health Service Center, Dokkyo Medical University"}]},"item_2_title_3":{"attribute_name":"論文名よみ","attribute_value_mlt":[{"subitem_title":"トウ イカ ダイガク ガクセイ ・ フゾク カンゴ センモン ガッコウ ガクセイ ニ オケル B ガタ カンエン ワクチン セッシュ セイセキ ノ ケントウ : ワクチン セッシュ 1 シリーズ シュウリョウゴ オヨビ 1 ネンゴ ノ HBS コウタイカ ノ スイイ ニ ツ イテ"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"渡邉, 菜穂美"},{"creatorName":"ワタナベ, ナオミ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"石川, 弥生"},{"creatorName":"イシカワ, ヤヨイ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"知花, 洋子"},{"creatorName":"チバナ, ヨウコ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"大類, 方巳"},{"creatorName":"オオルイ, マサミ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Watanabe, Naomi","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Ishikawa, Yayoi","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Chibana, Yoko","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Masami, Ohrui","creatorNameLang":"en"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2017-05-24"}],"displaytype":"detail","filename":"KJ00009895939.pdf","filesize":[{"value":"428.6 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"KJ00009895939.pdf","url":"https://dmu.repo.nii.ac.jp/record/1263/files/KJ00009895939.pdf"},"version_id":"64af04b9-61e6-464e-ad27-7804b1e82fec"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"B型肝炎ウイルス"},{"subitem_subject":"B型肝炎ワクチン"},{"subitem_subject":"HBs抗体"},{"subitem_subject":"HBs抗体陰性化"},{"subitem_subject":"医療系学生"},{"subitem_subject":"Hepatitis B Virus(hbv)","subitem_subject_language":"en"},{"subitem_subject":"Hepatitis B Vaccine","subitem_subject_language":"en"},{"subitem_subject":"Anti-hbs","subitem_subject_language":"en"},{"subitem_subject":"Seronegative Status","subitem_subject_language":"en"},{"subitem_subject":"Students","subitem_subject_language":"en"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"当医科大学学生・附属看護専門学校学生におけるB型肝炎ワクチン接種成績の検討 : ワクチン接種1シリーズ終了後および1年後のHBs抗体価の推移について","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"当医科大学学生・附属看護専門学校学生におけるB型肝炎ワクチン接種成績の検討 : ワクチン接種1シリーズ終了後および1年後のHBs抗体価の推移について"},{"subitem_title":"Evaluation of Usefulness of Hepatitis B Vaccination in Students at Dokkyo Medical University","subitem_title_language":"en"}]},"item_type_id":"2","owner":"3","path":["74"],"pubdate":{"attribute_name":"公開日","attribute_value":"2017-05-24"},"publish_date":"2017-05-24","publish_status":"0","recid":"1263","relation_version_is_last":true,"title":["当医科大学学生・附属看護専門学校学生におけるB型肝炎ワクチン接種成績の検討 : ワクチン接種1シリーズ終了後および1年後のHBs抗体価の推移について"],"weko_creator_id":"3","weko_shared_id":3},"updated":"2023-06-20T16:01:15.230567+00:00"}