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  1. Dokkyo Journal of Medical Sciences
  2. 42(2) 2015

前眼部螢光測定装置による水晶体自発螢光の生体内定量

https://dmu.repo.nii.ac.jp/records/1265
https://dmu.repo.nii.ac.jp/records/1265
c670b6ab-8cb7-411c-b1eb-eb4e1666384b
名前 / ファイル ライセンス アクション
KJ00009895941.pdf KJ00009895941.pdf (453.0 kB)
Item type [ELS]学術雑誌論文 / Journal Article(1)
公開日 2017-05-24
タイトル
タイトル 前眼部螢光測定装置による水晶体自発螢光の生体内定量
タイトル
言語 en
タイトル Quantification of Autofluorescence in Human Lens
言語
言語 jpn
キーワード
主題 水晶体
キーワード
主題 自発螢光
キーワード
主題 前眼部螢光測定装置
キーワード
主題 加齢
キーワード
言語 en
主題 Autofluorescence
キーワード
言語 en
主題 Fluorophotometer
キーワード
言語 en
主題 Human Lens
キーワード
言語 en
主題 Aging
資源タイプ
資源タイプ識別子 http://purl.org/coar/resource_type/c_6501
資源タイプ journal article
雑誌書誌ID
収録物識別子 AA00629581
論文名よみ
タイトル ゼンガンブ ケイコウ ソクテイ ソウチ ニ ヨル スイショウタイ ジハツ ケイコウ ノ セイタイ ナイ テイリョウ
著者 中村, 昌弘

× 中村, 昌弘

WEKO 6264

中村, 昌弘

ja-Kana ナカムラ, マサヒロ

Search repository
新井, 清美

× 新井, 清美

WEKO 6265

新井, 清美

ja-Kana アライ, キヨミ

Search repository
小俣, 仁

× 小俣, 仁

WEKO 6266

小俣, 仁

ja-Kana オマタ, ヒトシ

Search repository
林, 振民

× 林, 振民

WEKO 6267

林, 振民

ja-Kana ハヤシ, シンミン

Search repository
吉田, 紳一郎

× 吉田, 紳一郎

WEKO 6268

吉田, 紳一郎

ja-Kana ヨシダ, シンイチロウ

Search repository
筑田, 眞

× 筑田, 眞

WEKO 6269

筑田, 眞

ja-Kana チクダ, マコト

Search repository
Nakamura, Masahiro

× Nakamura, Masahiro

WEKO 6270

en Nakamura, Masahiro

Search repository
Arai, Kiyomi

× Arai, Kiyomi

WEKO 6271

en Arai, Kiyomi

Search repository
Omata, Hitoshi

× Omata, Hitoshi

WEKO 6272

en Omata, Hitoshi

Search repository
Hayashi, Shimmin

× Hayashi, Shimmin

WEKO 6273

en Hayashi, Shimmin

Search repository
Yoshida, Shinichiro

× Yoshida, Shinichiro

WEKO 6274

en Yoshida, Shinichiro

Search repository
Chikuda, Makoto

× Chikuda, Makoto

WEKO 6275

en Chikuda, Makoto

Search repository
著者所属(日)
獨協医科大学越谷病院 眼科:新越谷アイクリニック
著者所属(日)
獨協医科大学越谷病院 眼科:新越谷アイクリニック
著者所属(日)
獨協医科大学越谷病院 眼科:新越谷アイクリニック
著者所属(日)
獨協医科大学越谷病院 眼科:いきいき眼科
著者所属(日)
獨協医科大学越谷病院 眼科:吉田眼科病院
著者所属(日)
獨協医科大学越谷病院 眼科:吉田眼科病院
著者所属(英)
en
Department Of Ophthalmology, Koshigaya Hospital, Dokkyo Medical University:Shinkoshigaya Eye Clinic
著者所属(英)
en
Department Of Ophthalmology, Koshigaya Hospital, Dokkyo Medical University:Shinkoshigaya Eye Clinic
著者所属(英)
en
Department Of Ophthalmology, Koshigaya Hospital, Dokkyo Medical University:Shinkoshigaya Eye Clinic
著者所属(英)
en
Department Of Ophthalmology, Koshigaya Hospital, Dokkyo Medical University:Lively Eye Clinic
著者所属(英)
en
Department Of Ophthalmology, Koshigaya Hospital, Dokkyo Medical University:Yoshida Eye Hospital
著者所属(英)
en
Department Of Ophthalmology, Koshigaya Hospital, Dokkyo Medical University:Yoshida Eye Hospital
記事種別(日)
内容記述タイプ Other
内容記述 原著
抄録(日)
内容記述タイプ Other
内容記述 前眼部螢光測定装置を改良し,励起側中心波長Ex 340 nm(260-390 nm),螢光側中心波長Em 440 nm(400-710 nm)で白内障のない水晶体の自発螢光をin vivoで測定した.水晶体自発螢光値の年代別変化は,10歳代38.7±8.4(photoncount/msec),20歳代56.0±15.4,30歳代74.4±14.4,40歳代94.2±28.6,50歳代115.3±27.0,60歳代113.8±32.3で,50歳代まで加齢とともに増加し,水晶体の自発螢光は年齢と有意な正の相関を示した(r=0.76,p<0.01).水晶体の自発螢光値の増加は加齢現象を示す指標の一つであり,本測定装置により水晶体の加齢変化を非侵襲かつ簡便に測定できると考えられた.
抄録(英)
内容記述タイプ Other
内容記述 To investigate changes in lens autofluorescence with aging, we measured the in vivo autofluorescence of non-cataract lenses using an anterior fluorophotometer. The FL-500 anterior fluorophotometer is a non-invasive, simplified quantification measuring device with improved filters of optimum wavelengths to measure lens autofluorescence(excitation filter:center 340 nm(260-390 nm), emission filter: center 440 nm(400-710 nm)). The subjects were 410 non-cataract eyes from volunteers aged 8-69 without systemic disease such as diabetes. Autofluorescence was compared between lenses grouped according to age(decades). Thus, autofluorescence was 38.7±8.4(photoncount/msec) for the second decade of life(10-19 years old), 56.0±15.4 for the third(20-29 years old), 74.4±14.4 for the fourth (30-39 years old), 94.2±28.6 for the fifth(40-49 years old), 115.3±27.0 for the sixth(50-59 years old), and 113.8±32.3 for the seventh(60-69 years old). These measurements increased significantly from the first to the fifth decade(p< 0.01), so lens autofluorescence was significantly correlated with age(r=0.76, p<0.01). In conclusion, the autofluorescence of non-cataract lenses increases with age from 10 to 50 years, and therefore represents a good indication of aging.
書誌情報 Dokkyo journal of medical sciences

巻 42, 号 2, p. 77-82, 発行日 2015-07-25
ISSN
収録物識別子 03855023
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