@article{oai:dmu.repo.nii.ac.jp:00001288,
 author = {Scholz, Hans and Matsushita, Yasushi and Krueger, Ulf and Wunsch, Matthias and Lorenz, Uwe and Petzold, Karen and Zidane, Djamal},
 issue = {1},
 journal = {Dokkyo journal of medical sciences},
 month = {Mar},
 note = {Background:Acceptance has grown for single-needle dialysis when a vascular access is not suited for the insertion of two needles. Its impact on flow patterns was unknown. Methods:We produced transparent life-size models of arteriovenous(AV)fistulas and AV grafts that we placed into a pulsatile flow system to examine flow characteristics during simulated dialysis cycles. For this purpose we injected dye, and recorded and analyzed the resulting flow patterns using suitable software tools. Results:There is a definite flow reversal during the arterial phases in both AV fistulas and -less pronounced-in AV grafts leading to flow oscillations. Conclusion:Flow oscillations initiate subintimal hyperplasia possibly leading to stenoses in vivo. Reversal of the flow direction may also cause steal phenomena in the poorly perfused distal extremity. Single-needle dialysis should therefore be avoided if possible., Original},
 pages = {1--4},
 title = {Fluid Dynamics of Single-needle Dialysis in an Experimental Model},
 volume = {43},
 year = {2016}
}