{"created":"2023-06-20T14:26:10.058912+00:00","id":1494,"links":{},"metadata":{"_buckets":{"deposit":"d760bfef-6398-4c4f-b485-166f4a04454b"},"_deposit":{"created_by":14,"id":"1494","owners":[14],"pid":{"revision_id":0,"type":"depid","value":"1494"},"status":"published"},"_oai":{"id":"oai:dmu.repo.nii.ac.jp:00001494","sets":["81:87"]},"author_link":["4073","6487","5807","4069","6497","5812","5809"],"item_10001_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2017-07-25","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"2","bibliographicPageEnd":"155","bibliographicPageStart":"151","bibliographicVolumeNumber":"44","bibliographic_titles":[{"bibliographic_title":"Dokkyo Journal of Medical Sciences"}]}]},"item_10001_description_34":{"attribute_name":"要旨","attribute_value_mlt":[{"subitem_description":"Genetic factors are responsible for approximately 15％ of male infertility. The azoospermia factors AZFa, AZFb（P5/proximal P1）, and AZFc（b2/b4） present on Yq are most important for spermatogenesis. Here,\nwe evaluated frequencies of microdeletions of AZFa, AZFb, AZFc in azoospermia due to spermatogenic\ndysfunction in the Japanese population. The overall prevalence of Y chromosome microdeletions in infertile\nmen was 8.1％（79/980）. The prevalence of Y chromosome microdeletions in AZFa, AZFb, AZFabc, AZFbc （P5/distal P1 or P4/distal P1） and AZFc was 0.1％ , 0.8％ , 0.7％ , 2.0％ and 4.4％ , respectively. Microdissection for testicular sperm extraction failed in all patients with microdeletion in AZFa, AZFb, AZFabc, and AZFbc, although sperm could be retrieved in 28/43 patients with AZFc deletions（62.2％）. The presence of an AZFc deletion was associated with significantly better sperm retrieval than the 33.0％ retrieval rate in idiopathic non-deleted azoospermic men undergoing microdissection for testicular sperm\nextraction at our institution during the study period. We conclude that Y chromosome microdeletion testing is essential for genetic and preoperative counseling in these patients.","subitem_description_type":"Other"}]},"item_10001_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"獨協医学会"}]},"item_10001_source_id_11":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AA00629581","subitem_source_identifier_type":"NCID"}]},"item_10001_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"03855023","subitem_source_identifier_type":"ISSN"}]},"item_10001_text_24":{"attribute_name":"著者所属","attribute_value_mlt":[{"subitem_text_value":"Department of Urology, Dokkyo Medical University Koshigaya Hospital"},{"subitem_text_value":"Department of Urology, Dokkyo Medical University Koshigaya Hospital"},{"subitem_text_value":"Department of Urology, Dokkyo Medical University Koshigaya Hospital"},{"subitem_text_value":"Department of Urology, Dokkyo Medical University Koshigaya Hospital"},{"subitem_text_value":"Department of Urology, Dokkyo Medical University Koshigaya Hospital"},{"subitem_text_value":"Department of Urology, Dokkyo Medical University Koshigaya Hospital"},{"subitem_text_value":"Department of Urology, Dokkyo Medical University Koshigaya Hospital"}]},"item_10001_text_28":{"attribute_name":"表示順","attribute_value_mlt":[{"subitem_text_value":"4"}]},"item_10001_text_33":{"attribute_name":"記事種別","attribute_value_mlt":[{"subitem_text_value":"Original"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Iwahata, Toshiyuki","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Kobori, Yoshitomo","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Shimomura, Yukihito","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Suzuki, Keisuke","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Shin, Takeshi","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Song, Shigehiro","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Okada, Hiroshi","creatorNameLang":"en"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2018-07-10"}],"displaytype":"detail","filename":"DJMS-44-2-4.pdf","filesize":[{"value":"64.2 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"DJMS-44-2-Iwahata-本文","url":"https://dmu.repo.nii.ac.jp/record/1494/files/DJMS-44-2-4.pdf"},"version_id":"28192071-cddf-4b22-9e9b-d50f2bd1a02b"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Male infertility","subitem_subject_scheme":"Other"},{"subitem_subject":"Azoospermia","subitem_subject_scheme":"Other"},{"subitem_subject":"Testicular sperm extraction","subitem_subject_scheme":"Other"},{"subitem_subject":"Y chromosome","subitem_subject_scheme":"Other"},{"subitem_subject":"Y microdeletions","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Spermatogenic Dysfunction in Azoospermic Japanese Men Caused by Y Chromosome Microdeletions","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Spermatogenic Dysfunction in Azoospermic Japanese Men Caused by Y Chromosome Microdeletions"}]},"item_type_id":"10001","owner":"14","path":["87"],"publish_date":"2018-07-10","publish_status":"0","recid":"1494","relation_version_is_last":true,"title":["Spermatogenic Dysfunction in Azoospermic Japanese Men Caused by Y Chromosome Microdeletions"],"weko_creator_id":"14","weko_shared_id":-1},"updated":"2023-06-20T15:45:22.145963+00:00"}