{"created":"2023-06-20T14:26:10.318397+00:00","id":1500,"links":{},"metadata":{"_buckets":{"deposit":"8b32de3e-cb9d-41e4-a77d-8e223767238a"},"_deposit":{"created_by":3,"id":"1500","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"1500"},"status":"published"},"_oai":{"id":"oai:dmu.repo.nii.ac.jp:00001500","sets":["81:91"]},"author_link":["6904","1299","723","411","360","6243","7014","1305","2778","720"],"item_10001_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2018-03-25","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1","bibliographicPageEnd":"8","bibliographicPageStart":"1","bibliographicVolumeNumber":"45","bibliographic_titles":[{"bibliographic_title":"Dokkyo Journal of Medical Sciences"}]}]},"item_10001_description_34":{"attribute_name":"要旨","attribute_value_mlt":[{"subitem_description":"Objective：To investigate the significance of additional hepatitis B （HB） vaccination in medical students who were unresponsive to a primary vaccine series or those who had lost antibody to hepatitis B surface antigen （anti-HBs）.\n\nMethods：Subjects were followed up for 3 years after completion of a primary HB vaccine series. One additional dose was given to those who lost the anti-HBs within 3 years after the initial series, while 3 doses were given to those who had not responded to the initial vaccination. Subjects：100 medical students （59 men and 41 women；mean age on admission to university, 19.4±1.6 years） enrolled at the School of Medicine, Dokkyo Medical University in April 2012.\n\nResults：The rate of positivity for anti-HBs was 98％ soon after completion of the primary HB vaccine series and decreased without the need for additional vaccination to 79％, 61％, and 55％ at 1, 2, and 3 years after the primary series, respectively. Eighteen vaccinated subjects （18％） lost the anti-HBs 2 years after the primary series, and all of them responded to 1 additional dose. Another 18 successfully vaccinated subjects （18％） were anti-HBs negative both 1 and 2 years after the primary series；17 of them responded to 1 additional dose. As for 2 subjects （2％） who were unresponsive to the primary series, 1 became anti-HBs-positive for the first time after 3 additional doses given 2 years after the primary series.\n\nConclusion：A number of students became or remained anti-HBs negative after the primary HB vaccination, indicating that its timing and dose of additional vaccination need to be studied further to evaluate its utility.\n","subitem_description_type":"Other"}]},"item_10001_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"獨協医学会"}]},"item_10001_source_id_11":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AA00629581","subitem_source_identifier_type":"NCID"}]},"item_10001_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"03855023","subitem_source_identifier_type":"ISSN"}]},"item_10001_text_24":{"attribute_name":"著者所属","attribute_value_mlt":[{"subitem_text_value":"Department of Health Care, Dokkyo Medical University Hospital, Tochigi, Japan"},{"subitem_text_value":"Department of Health Care, Dokkyo Medical University Hospital, Tochigi, Japan"},{"subitem_text_value":"Department of Health Care, Dokkyo Medical University Hospital, Tochigi, Japan"},{"subitem_text_value":"Department of Health Care, Dokkyo Medical University Hospital, Tochigi, Japan"},{"subitem_text_value":"Department of Health Care, Dokkyo Medical University Hospital, Tochigi, Japan:Health Service Center, Dokkyo Medical University, Tochigi, Japan"},{"subitem_text_value":"Department of Gastroenterology, Dokkyo Medical University, Tochigi, Japan"},{"subitem_text_value":"Department of Gastroenterology, Dokkyo Medical University, Tochigi, Japan"},{"subitem_text_value":"Department of Gastroenterology, Dokkyo Medical University, Tochigi, Japan"},{"subitem_text_value":"Department of Gastroenterology, Dokkyo Medical University, Tochigi, Japan"},{"subitem_text_value":"Department of Gastroenterology, Dokkyo Medical University, Tochigi, Japan"}]},"item_10001_text_28":{"attribute_name":"表示順","attribute_value_mlt":[{"subitem_text_value":"2"}]},"item_10001_text_33":{"attribute_name":"記事種別","attribute_value_mlt":[{"subitem_text_value":"Original"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Ohyatsu, Mariko","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Ishikawa, Yayoi","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Chibana, Yoko","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Watanabe, Naomi","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Ohrui, Masami","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Tsuchida, Kohei","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Tominaga, Keiichi","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Murohisa, Toshimitsu","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Iijima, Makoto","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Hiraishi, Hideyuki","creatorNameLang":"en"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2018-07-10"}],"displaytype":"detail","filename":"DJMS-45-1-2.pdf","filesize":[{"value":"214.3 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"DJMS-45-1-Ohyatsu-本文","url":"https://dmu.repo.nii.ac.jp/record/1500/files/DJMS-45-1-2.pdf"},"version_id":"fc8959ed-90dc-4092-b0f1-1a50d0149fbf"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"hepatitis B virus","subitem_subject_scheme":"Other"},{"subitem_subject":"HBV","subitem_subject_scheme":"Other"},{"subitem_subject":"hepatitis B(HB)vaccine","subitem_subject_scheme":"Other"},{"subitem_subject":"anti-HBs","subitem_subject_scheme":"Other"},{"subitem_subject":"additional vaccination","subitem_subject_scheme":"Other"},{"subitem_subject":"medical students","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Results of Hepatitis B Vaccination 3 Years After a Primary Vaccine Series in Medical Students","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Results of Hepatitis B Vaccination 3 Years After a Primary Vaccine Series in Medical Students"}]},"item_type_id":"10001","owner":"3","path":["91"],"publish_date":"2018-07-10","publish_status":"0","recid":"1500","relation_version_is_last":true,"title":["Results of Hepatitis B Vaccination 3 Years After a Primary Vaccine Series in Medical Students"],"weko_creator_id":"3","weko_shared_id":3},"updated":"2023-06-20T15:45:54.807016+00:00"}