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Changing from a Dipeptidyl Peptidase (DPP)-4 Inhibitor to Oral Semaglutide in Patients with Poorly Controlled Type 2 Diabetes Mellitus: An Observational Study
https://dmu.repo.nii.ac.jp/records/2000043
https://dmu.repo.nii.ac.jp/records/20000438bff2097-97cc-476a-a8fb-07b697ce6c5d
| 名前 / ファイル | ライセンス | アクション |
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DKMJ-2-1-4.pdf (234 KB)
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||||||||||||
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| タイトル | ||||||||||||||||
| タイトル | Changing from a Dipeptidyl Peptidase (DPP)-4 Inhibitor to Oral Semaglutide in Patients with Poorly Controlled Type 2 Diabetes Mellitus: An Observational Study | |||||||||||||||
| 言語 | en | |||||||||||||||
| 言語 | ||||||||||||||||
| 言語 | eng | |||||||||||||||
| キーワード | ||||||||||||||||
| 言語 | en | |||||||||||||||
| 主題Scheme | Other | |||||||||||||||
| 主題 | oral semaglutide | |||||||||||||||
| キーワード | ||||||||||||||||
| 言語 | en | |||||||||||||||
| 主題Scheme | Other | |||||||||||||||
| 主題 | DPP4 inhibitor | |||||||||||||||
| キーワード | ||||||||||||||||
| 言語 | en | |||||||||||||||
| 主題Scheme | Other | |||||||||||||||
| 主題 | type 2 diabetes | |||||||||||||||
| 資源タイプ | ||||||||||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||||||||||
| 資源タイプ | journal article | |||||||||||||||
| 著者 |
Takebayashi, Kohzo
× Takebayashi, Kohzo
× Yamauchi, Mototaka
× Hara, Kenji
× Tsuchiya, Takafumi
× Hashimoto, Koshi
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| 書誌情報 |
en : Dokkyo Medical Journal 巻 2, 号 2, p. 123-129, 発行日 2023-06-25 |
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| 内容記述 | ||||||||||||||||
| 内容記述タイプ | Abstract | |||||||||||||||
| 内容記述 | Aims: The aim of the present study was to evaluate the effect of changing from a dipeptidyl peptidase (DPP)-4 inhibitor to oral semaglutide on glycemic control, as reflected by hemoglobin A1c (HbA1c), occasional plasma glucose (PG) and glycoalbumin (GA), and body weight (BW) in routine clinical practice. Patients and Methods: A search of electronic medical records was performed for patients treated with a DPP4 inhibitor for diabetes mellitus and who were then changed to oral semaglutide because of relatively poor glycemic control from December 2021 to March 2022. A total of 19 patients met these inclusion criteria. Data for these patients were evaluated until the end of August 2022. Results: HbA1c and occasional PG were significantly decreased compared to baseline (the time of changing treatment) at 4 months and at the final visit (a mean of about 6 months). GA was significantly decreased from baseline at 1 month, 4 months, and at the final visit. BW was also significantly decreased from baseline at 4 months and the final visit. There were no statistically significant changes in low-density lipoprotein cholesterol (LDL-C), triglyceride (TG) or estimated glomerular filtration rate (eGFR). Conclusion: These results of the present study show that changing from a DPP4 inhibitor to oral semaglutide significantly improved glycemic control, as reflected by HbA1c, occasional PG and GA, and led to a significant reduction in BW after an observational period of over 4 months. |
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| 言語 | en | |||||||||||||||
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| 出版者 | Dokkyo Medical Society | |||||||||||||||
| ISSN | ||||||||||||||||
| 収録物識別子タイプ | EISSN | |||||||||||||||
| 収録物識別子 | 2436-522X | |||||||||||||||
| 書誌レコードID | ||||||||||||||||
| 収録物識別子タイプ | NCID | |||||||||||||||
| 収録物識別子 | AA12941861 | |||||||||||||||
| DOI | ||||||||||||||||
| 関連タイプ | isIdenticalTo | |||||||||||||||
| 識別子タイプ | DOI | |||||||||||||||
| 関連識別子 | https://doi.org/10.51040/dkmj.2022-058 | |||||||||||||||
| 出版タイプ | ||||||||||||||||
| 出版タイプ | VoR | |||||||||||||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||||||||||||
