| Item type |
学術雑誌論文 / Journal Article(1) |
| タイトル |
|
|
タイトル |
Total Neoadjuvant Therapy for Rectal Cancer: the Case Report |
|
言語 |
en |
| 言語 |
|
|
言語 |
eng |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
Rectal cancer |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
Total neoadjuvant therapy |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
Safety |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| 著者 |
Ihara, Keisuke
Nakamura, Takatoshi
Takayanagi, Masashi
Fujita, Junki
Maeda, Yasunori
Nishi, Yusuke
Shibuya, Norisuke
Hachiya, Hiroyuki
Ishiduka, Mitsuru
Mise, Minori
Yamaguchi, Takeshi
Muroi, Hiroto
Nakagawa, Masatoshi
Suzuki, Kan
Nakajima, Masanobu
Morita, Shinji
Ejima, Yasuo
Kojima, Kazuyuki
Irisawa, Atsushi
|
| 書誌情報 |
en : Dokkyo Medical Journal
巻 2,
号 3,
p. 212-216,
発行日 2023-09-25
|
| 記事種別 |
|
|
|
Case Report |
| 内容記述 |
|
|
内容記述タイプ |
Abstract |
|
内容記述 |
We report a case of advanced rectal cancer that could be radically resected after total neoadjuvant therapy (TNT). A 65-year-old man underwent TNT for lower rectal cancer. The patient received a short course of chemoradiation therapy (CRT) at a total dose of 30 Gy to the pelvic area, including lateral lymph nodes, in fractions of 3 Gy administered five times a week over 10 days (days 1-5 and 8-12). The CRT was given in combination with S-1 at a dose of 80 mg twice daily on all days of radiotherapy. After CRT, the patient was scheduled to receive two cycles of S-1 + oxaliplatin (SOX) therapy. SOX was administered over 3 weeks (130 mg/m² oxaliplatin on days 20 and 41, and 80 mg oral S-1 on days 20-33 and 41-54). Robotically-assisted laparoscopic low anterior resection was performed on day 77. Histopathological findings showed only a small amount of residual tumor (residual tumor volume of less than 5%), and the radial margin was negative. There were no severe adverse events, postoperative complications, or functional disorders. These findings demonstrated the effectiveness and safety of TNT with short-term irradiation for rectal cancer. This regimen may be a new candidate for neoadjuvant treatment of previously untreated rectal cancer. |
|
言語 |
en |
| 出版者 |
|
|
出版者 |
Dokkyo Medical Society |
| ISSN |
|
|
収録物識別子タイプ |
EISSN |
|
収録物識別子 |
2436-522X |
| 書誌レコードID |
|
|
収録物識別子タイプ |
NCID |
|
収録物識別子 |
AA12941861 |
| DOI |
|
|
関連タイプ |
isIdenticalTo |
|
|
識別子タイプ |
DOI |
|
|
関連識別子 |
https://doi.org/10.51040/dkmj.2022-060 |
| 出版タイプ |
|
|
出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
DKMJ-2-3-4.pdf (1.2 MB)
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