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  1. Dokkyo Medical Journal
  2. 4(3) 2025

Coronary Computed Tomography Angiography for Observation of Stabilized Coronary Arterial Plaque after “Drug Intervention”: A Case Report

https://dmu.repo.nii.ac.jp/records/2000712
https://dmu.repo.nii.ac.jp/records/2000712
eeb90a03-1fc5-4774-955b-4fc4a4ad7165
名前 / ファイル ライセンス アクション
DKMJ-4-3-12.pdf DKMJ-4-3-12.pdf (972 KB)
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Item type 学術雑誌論文 / Journal Article(1)
タイトル
タイトル Coronary Computed Tomography Angiography for Observation of Stabilized Coronary Arterial Plaque after “Drug Intervention”: A Case Report
言語 en
言語
言語 eng
キーワード
言語 en
主題Scheme Other
主題 strike early-strike strong lipid-lowering strategy
キーワード
言語 en
主題Scheme Other
主題 low-density lipoprotein cholesterol
キーワード
言語 en
主題Scheme Other
主題 proprotein convertase subtilisin/kexin type 9 inhibitor
キーワード
言語 en
主題Scheme Other
主題 statins
資源タイプ
資源タイプ識別子 http://purl.org/coar/resource_type/c_6501
資源タイプ journal article
アクセス権
アクセス権 open access
アクセス権URI http://purl.org/coar/access_right/c_abf2
著者 Lu, Tianyang

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en Lu, Tianyang

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Yazawa, Hiroko

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en Yazawa, Hiroko

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Sakuma, Masashi

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Inoue, Riri

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en Inoue, Riri

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Hashimoto, Ryota

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Hirose, Suguru

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Waku, Ryutarou

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Yonezawa, Yutaka

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Koyabu, Yota

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Nishino, Setsu

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Kanaya, Tomoaki

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Toyoda, Shigeru

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書誌情報 en : Dokkyo Medical Journal

巻 4, 号 3, p. 260-267, 発行日 2025-06-25
記事種別
値 Case Report
内容記述
内容記述タイプ Abstract
内容記述 A 54-year-old woman with unstable angina underwent coronary stent deployment. She was started on rosuvastatin therapy before undergoing percutaneous coronary intervention (PCI). However, arriving at lowdensity lipoprotein cholesterol (LDL-C) levels lower than 70 mg/dL required more than a month of treatment. This was accomplished by increasing the rosuvastatin dose by 10 mg and adding ezetimibe. Chronic-phase coronary computed tomography angiography (CCTA) did not show stent restenosis but revealed plaque progression in the left main trunk (LMT). A combination of rosuvastatin, ezetimibe, and the proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitor was administered to promote regression of the plaque. Followup CCTA performed 12 months after the initial scan showed regression of the LMT plaque and the appearance of new calcification in the proximal plaque of the left anterior descending (LAD) artery. The aggressive lipid-lowering strategy that combined rosuvastatin, ezetimibe, and a PCSK9 inhibitor successfully achieved plaque regression without the occurrence of cardiovascular events.
言語 en
出版者
出版者 Dokkyo Medical Society
ISSN
収録物識別子タイプ EISSN
収録物識別子 2436-522X
書誌レコードID
収録物識別子タイプ NCID
収録物識別子 AA12941861
DOI
関連タイプ isIdenticalTo
識別子タイプ DOI
関連識別子 https://doi.org/10.51040/dkmj.2024-048
出版タイプ
出版タイプ VoR
出版タイプResource http://purl.org/coar/version/c_970fb48d4fbd8a85
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