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  1. Dokkyo Medical Journal
  2. 4(4) 2025

Clinical Characteristics of Obstructive Hypertrophic Cardiomyopathy and Other Conditions with Increased Left Ventricular Outflow Tract Pressure Gradient

https://dmu.repo.nii.ac.jp/records/2000715
https://dmu.repo.nii.ac.jp/records/2000715
b8e29ed6-01e6-4d46-8436-adc439762c61
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DKMJ-4-4-2.pdf DKMJ-4-4-2.pdf (284 KB)
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Item type 学術雑誌論文 / Journal Article(1)
タイトル
タイトル Clinical Characteristics of Obstructive Hypertrophic Cardiomyopathy and Other Conditions with Increased Left Ventricular Outflow Tract Pressure Gradient
言語 en
言語
言語 eng
キーワード
言語 en
主題Scheme Other
主題 obstructive hypertrophic cardiomyopathy
キーワード
言語 en
主題Scheme Other
主題 left ventricular outflow tract pressure gradient
キーワード
言語 en
主題Scheme Other
主題 left ventricular outflow tract obstruction
資源タイプ
資源タイプ識別子 http://purl.org/coar/resource_type/c_6501
資源タイプ journal article
アクセス権
アクセス権 open access
アクセス権URI http://purl.org/coar/access_right/c_abf2
著者 Kobayashi, Sayuki

× Kobayashi, Sayuki

en Kobayashi, Sayuki

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Itabashi, Yuji

× Itabashi, Yuji

en Itabashi, Yuji

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Hana, Shinsei

× Hana, Shinsei

en Hana, Shinsei

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Koshikawa, Yuri

× Koshikawa, Yuri

en Koshikawa, Yuri

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Higashi, Ayako

× Higashi, Ayako

en Higashi, Ayako

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Ishikawa, Tetsuya

× Ishikawa, Tetsuya

en Ishikawa, Tetsuya

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Nakahara, Shiro

× Nakahara, Shiro

en Nakahara, Shiro

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Sakai, Yoshihiko

× Sakai, Yoshihiko

en Sakai, Yoshihiko

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Taguchi, Isao

× Taguchi, Isao

en Taguchi, Isao

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書誌情報 en : Dokkyo Medical Journal

巻 4, 号 4, p. 283-289, 発行日 2025-08-25
記事種別
値 Original
内容記述
内容記述タイプ Abstract
内容記述 Purpose:
To estimate the clinical characteristics of obstructive hypertrophic cardiomyopathy (HOCM) and other diseases or conditions with left ventricular outflow tract obstruction (LVOTO).

Methods:
Forty cases (mean age 71 years, 31 women) with LVOTO (LVOT pressure gradient ≥ 30 mmHg) on resting transthoracic echocardiography were investigated and divided into two groups: HOCM group and other conditions (non HOCM group), and their clinical characteristics were compared. The mean follow-up period was 41 ± 8 months.

Results:
There were 17 patients (42.5%) in the HOCM group and 23 (57.5%) in the non HOCM group, with sigmoid septum being the most common (12 patients, 30%), followed by hypertensive heart (10%), takotsubo syndrome (7.5%). and small left ventricle with hyperkinetic wall motion (7.5%). Compared to the HOCM group, the non HOCM group was older (76 ± 10 vs. 67 ± 10 years, p = 0.006), had more frequent hypertension (HT) (78% vs. 47%, p = 0.041), and the mitral regurgitation severity at the first transthoracic echocardiography was significantly lower. Compared to the first LVOT velocity, the last LVOT velocity was significantly reduced in the HOCM group (4.6 ± 0.1 m/sec vs. 2.8 ± 1.8 m/sec, p = 0.001). However, there was no significant change in the non HOCM group (4.1 ± 1.0 m/sec vs. 3.3 ± 1.1 m/sec, p = 0.100). The frequency of cardiovascular events showed no significant difference between the 2 groups.

Conclusions:
This study showed different clinical background and change of LVOT velocity during follow-up periods in both groups. As the population ages, the patients with various LVOTO will increase further. It is important to investigate factors causing LVOTO and comprehensive management are required individually.
言語 en
出版者
出版者 Dokkyo Medical Society
ISSN
収録物識別子タイプ EISSN
収録物識別子 2436-522X
書誌レコードID
収録物識別子タイプ NCID
収録物識別子 AA12941861
DOI
関連タイプ isIdenticalTo
識別子タイプ DOI
関連識別子 https://doi.org/10.51040/dkmj.2024-031
出版タイプ
出版タイプ VoR
出版タイプResource http://purl.org/coar/version/c_970fb48d4fbd8a85
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