| Item type |
学術雑誌論文 / Journal Article(1) |
| タイトル |
|
|
タイトル |
A Case of Rheumatoid Meningitis without Symptoms of Arthritis and IgG4-positive Cellular Infiltration on Brain Biopsy |
|
言語 |
en |
| 言語 |
|
|
言語 |
eng |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
rheumatoid meningitis |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
anti-cyclic citrullinated peptide antibody |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
IgG4-related disorders |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
malignant tumors |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| アクセス権 |
|
|
アクセス権 |
open access |
|
アクセス権URI |
http://purl.org/coar/access_right/c_abf2 |
| 著者 |
Hayashi, Mizuki
Onoue, Hiroyuki
Owada, Takayoshi
Ban, Shinichi
Takano, Issei
Kobayashi, Satoru
Miyamoto, Tomoyuki
|
| 書誌情報 |
en : Dokkyo Medical Journal
巻 4,
号 4,
p. 329-336,
発行日 2025-08-25
|
| 記事種別 |
|
|
値 |
Case Report |
| 内容記述 |
|
|
内容記述タイプ |
Abstract |
|
内容記述 |
A 68-year-old man presented with a chronic headache, without signs of meningeal irritation, at the age of 67. Diffusion-weighted and FLAIR MRI of the head revealed hyperintense signal areas in the white matter of the right parietal lobe and the subarachnoid space within the falx cerebri, with enhancement of the pia mater. Serum and cerebrospinal fluid (CSF) anti-cyclic citrullinated peptide antibody (ACPA) levels, as well as the intrathecal ACPA antibody titer index (ACPA index), were elevated. Although serum IgG4 levels were normal, brain biopsy demonstrated an IgG4-positive cellular infiltrate exceeding 40% in the cerebral pia mater. Steroid treatment led to an improvement in meningitis, along with a reduction in CSF ACPA levels and the ACPA index. These findings suggest a shared pathogenic mechanism between rheumatic meningitis andIgG4-associated leptomeningitis. |
|
言語 |
en |
| 出版者 |
|
|
出版者 |
Dokkyo Medical Society |
| ISSN |
|
|
収録物識別子タイプ |
EISSN |
|
収録物識別子 |
2436-522X |
| 書誌レコードID |
|
|
収録物識別子タイプ |
NCID |
|
収録物識別子 |
AA12941861 |
| DOI |
|
|
関連タイプ |
isIdenticalTo |
|
|
識別子タイプ |
DOI |
|
|
関連識別子 |
https://doi.org/10.51040/dkmj.2024-050 |
| 出版タイプ |
|
|
出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
DKMJ-4-4-7.pdf (572 KB)
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