| Item type |
学術雑誌論文 / Journal Article(1) |
| タイトル |
|
|
タイトル |
Locally Advanced Rectal Cancer Achieving Clinical Complete Response after Total Neoadjuvant Therapy and Undergoing Follow-up: A Case Report |
|
言語 |
en |
| 言語 |
|
|
言語 |
eng |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
rectal cancer |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
non-operative management |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
pathological complete response |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| アクセス権 |
|
|
アクセス権 |
open access |
|
アクセス権URI |
http://purl.org/coar/access_right/c_abf2 |
| 著者 |
Nakamura, Takatoshi
Ejima, Yasuo
Hachiya, Hiroyuki
Shibuya, Norisuke
Ihara, Keisuke
Nishi, Yusuke
Kono, Takahiro
Ishizuka, Mitsuru
Ishida, Kazuyuki
Mizushima, Tsunekazu
|
| 書誌情報 |
en : Dokkyo Medical Journal
巻 4,
号 4,
p. 346-351,
発行日 2025-08-25
|
| 記事種別 |
|
|
値 |
Case Report |
| 内容記述 |
|
|
内容記述タイプ |
Abstract |
|
内容記述 |
We report the case of a 79-year-old man with locally advanced rectal cancer (LARC) who underwent total neoadjuvant therapy (TNT). Treatment consisted of chemoradiotherapy (CRT) delivered to the pelvic region (including the lateral lymph nodes) with a total dose of 30 Gy in 10 fractions of 3 Gy each. Concurrently with radiation therapy, S-1 (80 mg) was administered orally twice daily on all days of radiotherapy. Following CRT, systemic chemotherapy with the SOX regimen (S-1 and oxaliplatin) was administered for two cycles. Eight weeks after completion of radiation therapy, evaluation revealed no evidence of distant metastasis. Colonoscopy showed complete macroscopic disappearance of the tumor, and biopsy specimens revealed no evidence of residual cancer, confirming a complete clinical response (cCR). Although surgery was initially planned after TNT, the patient strongly preferred non-operative management (NOM). The patient has maintained cCR for two years following NOM, making this a valuable case to report. |
|
言語 |
en |
| 出版者 |
|
|
出版者 |
Dokkyo Medical Society |
| ISSN |
|
|
収録物識別子タイプ |
EISSN |
|
収録物識別子 |
2436-522X |
| 書誌レコードID |
|
|
収録物識別子タイプ |
NCID |
|
収録物識別子 |
AA12941861 |
| DOI |
|
|
関連タイプ |
isIdenticalTo |
|
|
識別子タイプ |
DOI |
|
|
関連識別子 |
https://doi.org/10.51040/dkmj.2025-008 |
| 出版タイプ |
|
|
出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |