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Effect of Switching from Dulaglutide to Oral Semaglutide in Patients with Type 2 Diabetes: A Retrospective Observational Study
https://dmu.repo.nii.ac.jp/records/2000835
https://dmu.repo.nii.ac.jp/records/20008352e206d0e-1345-4919-957c-af742c967644
| 名前 / ファイル | ライセンス | アクション |
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DKMJ-4-6-4.pdf (130 KB)
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||||||||||||
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| タイトル | ||||||||||||||||
| タイトル | Effect of Switching from Dulaglutide to Oral Semaglutide in Patients with Type 2 Diabetes: A Retrospective Observational Study | |||||||||||||||
| 言語 | en | |||||||||||||||
| 言語 | ||||||||||||||||
| 言語 | eng | |||||||||||||||
| キーワード | ||||||||||||||||
| 言語 | en | |||||||||||||||
| 主題Scheme | Other | |||||||||||||||
| 主題 | dulaglutide | |||||||||||||||
| キーワード | ||||||||||||||||
| 言語 | en | |||||||||||||||
| 主題Scheme | Other | |||||||||||||||
| 主題 | oral semaglutide | |||||||||||||||
| キーワード | ||||||||||||||||
| 言語 | en | |||||||||||||||
| 主題Scheme | Other | |||||||||||||||
| 主題 | type 2 diabetes | |||||||||||||||
| 資源タイプ | ||||||||||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||||||||||
| 資源タイプ | journal article | |||||||||||||||
| アクセス権 | ||||||||||||||||
| アクセス権 | open access | |||||||||||||||
| アクセス権URI | http://purl.org/coar/access_right/c_abf2 | |||||||||||||||
| 著者 |
Takebayashi, Kohzo
× Takebayashi, Kohzo
× Yamauchi, Mototaka
× Hara, Kenji
× Tsuchiya, Takafumi
× Hashimoto, Koshi
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| 書誌情報 |
en : Dokkyo Medical Journal 巻 4, 号 6, p. 454-459, 発行日 2025-12-25 |
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| 記事種別 | ||||||||||||||||
| 値 | Original | |||||||||||||||
| 内容記述 | ||||||||||||||||
| 内容記述タイプ | Abstract | |||||||||||||||
| 内容記述 | Aims: The current study was designed to evaluate the effect of switching from subcutaneous dulaglutide 0.75 mg weekly to oral semaglutide 7 mg daily on glycemic control, as reflected by hemoglobin A1c (HbA1c), occasional plasma glucose (PG) and glycoalbumin (GA) in real-world clinical practice in our hospital. Patients and Methods: A search of electronic medical records from January to September 2023 was performed for patients who had received dulaglutide for type 2 diabetes and were switched to oral semaglutide because of a chronic shortage of the supply of dulaglutide. A total of 19 patients were enrolled and data for these patients were evaluated until the end of March 2024. Results: All patients continued to take oral semaglutide during the observational period after the switch. After the change to oral semaglutide, there were no significant differences in HbA1c, PG and GA among time points of the final visit before baseline, at baseline (the time of the switch), and after 3 and 6 months. Low-density lipoprotein cholesterol (LDL-C), estimated glomerular filtration rate (eGFR), and body weight (BW) also did not differ significantly among all of these time points. Conclusion: A switch from subcutaneous dulaglutide 0.75 mg weekly to oral semaglutide 7 mg daily did not influence glycemic control, as reflected by HbA1c, PG and GA levels, or LDL-C, eGFR, and BW over a 6-month observational period. The tolerability to this change was basically satisfactory. |
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| 言語 | en | |||||||||||||||
| 出版者 | ||||||||||||||||
| 出版者 | Dokkyo Medical Society | |||||||||||||||
| ISSN | ||||||||||||||||
| 収録物識別子タイプ | EISSN | |||||||||||||||
| 収録物識別子 | 2436-522X | |||||||||||||||
| 書誌レコードID | ||||||||||||||||
| 収録物識別子タイプ | NCID | |||||||||||||||
| 収録物識別子 | AA12941861 | |||||||||||||||
| DOI | ||||||||||||||||
| 関連タイプ | isIdenticalTo | |||||||||||||||
| 識別子タイプ | DOI | |||||||||||||||
| 関連識別子 | https://doi.org/10.51040/dkmj.2025-027 | |||||||||||||||
| 出版タイプ | ||||||||||||||||
| 出版タイプ | VoR | |||||||||||||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||||||||||||
