@article{oai:dmu.repo.nii.ac.jp:00002116,
 author = {Furuichi, Masahito and Ishimitsu, Toshihiko},
 issue = {2},
 journal = {Dokkyo Journal Of Medical Sciences},
 month = {Jul},
 note = {In order to prevent cardiovascular events and organ injuries in hypertensive patients, strict blood pressure（BP）control over 24 hours  is of utmost importance. In addition to the BP level, it has been indicatedthat the variabilities of blood pressure during a day or between visits also influence the risk of cardiovascular disorders. This study aimed to delineate the factors relating to the variations of office and home BPs throughout a year in hypertensive outpatients under antihypertensive therapy. The office BP value（131/77 mmHg）was comparable to the morning home BP（130/76）, but was higher compared to the evening home BP（126/73）, however, the coefficient of variation（CV）values were comparable between the office and the home BPs. Correlations of BP and CV were stronger between the morning and the evening home BPs than between the office and the home BPs. The CV of systolic office BP was greater in patients with diabetes mellitus than the patients without diabetes（7.8 vs 6.1％）. In patients with chronic kidney disease, the CVs of diastolic office BP and evening home BP were greater than the patients without chronic kidney disease（8.0 vs 6.2％ and 8.1 vs 6.7％, respectively）. In addition, The CVs of diastolic morning and evening home BP were positively correlated with serum creatinine and a negatively correlated with estimated glomerular filtration rate. Patients with cardiovascular diseases such as stroke and coronary artery disease showed greater CV of diastolic morning home BP than the patients without cardiovascular diseases（8.2 vs 6.6％）. These results suggest that the home BP exhibits different variability from the office BP, and the BP variability is increased in high-risk hypertensive patients with diabetes mellitus, chronic kidney disease or cardiovascular diseases.},
 pages = {61--72},
 title = {Analysis of Factors Relating to Day-to-day Home Blood Pressure Variation in Hypertensive Patients},
 volume = {45},
 year = {2018}
}