{"created":"2023-06-20T14:26:32.779246+00:00","id":2117,"links":{},"metadata":{"_buckets":{"deposit":"14ade1e2-a00a-43de-bdd9-563567272dcc"},"_deposit":{"created_by":14,"id":"2117","owners":[14],"pid":{"revision_id":0,"type":"depid","value":"2117"},"status":"published"},"_oai":{"id":"oai:dmu.repo.nii.ac.jp:00002117","sets":["81:156"]},"author_link":["9839","9837","9833","9832","9841","9834","9840","9836","9838","9835"],"item_10001_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2018-07-25","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"2","bibliographicPageEnd":"79","bibliographicPageStart":"73","bibliographicVolumeNumber":"45","bibliographic_titles":[{"bibliographic_title":"Dokkyo Journal Of Medical Sciences"}]}]},"item_10001_description_34":{"attribute_name":"要旨","attribute_value_mlt":[{"subitem_description":"  Primary malignant melanoma of the esophagus（PMME）is extraordinarily rare with a high degree of malignancy and poor prognosis, and a standard therapy remains to be established. The anti-PD-1 antibody nivolumab is a promising agent for various cancers. To our knowledge, this is the first case report of PMME where a complete response was achieved using nivolumab. We report an 80-year-old woman who was diagnosed with PMME with bone metastasis and lymph node metastases. Although dacarbazine combined chemotherapy was performed and continued for six cycles, the primary tumor progressed and liver metastases appeared. The patient then received nivolumab monotherapy. After three cycles, nivolumab monotherapy for PMME resulted in a complete response as shown by positron emission tomography, computed tomography, and esophagogastroduodenoscopy. In our case, nivolumab exerted a curative effect on PMME, thus suggesting that nivolumab can be effective in the treatment of this rare disease.","subitem_description_type":"Other"}]},"item_10001_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"獨協医学会"}]},"item_10001_source_id_11":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AA00629581 ","subitem_source_identifier_type":"NCID"}]},"item_10001_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"03855023 ","subitem_source_identifier_type":"ISSN"}]},"item_10001_text_24":{"attribute_name":"著者所属","attribute_value_mlt":[{"subitem_text_value":"First Department of Surgery, Dokkyo Medical University"},{"subitem_text_value":"First Department of Surgery, Dokkyo Medical University"},{"subitem_text_value":"First Department of Surgery, Dokkyo Medical University"},{"subitem_text_value":"First Department of Surgery, Dokkyo Medical University"},{"subitem_text_value":"First Department of Surgery, Dokkyo Medical University"},{"subitem_text_value":"First Department of Surgery, Dokkyo Medical University"},{"subitem_text_value":"First Department of Surgery, Dokkyo Medical University"},{"subitem_text_value":"First Department of Surgery, Dokkyo Medical University"},{"subitem_text_value":"First Department of Surgery, Dokkyo Medical University"},{"subitem_text_value":"First Department of Surgery, Dokkyo Medical University"}]},"item_10001_text_33":{"attribute_name":"記事種別","attribute_value_mlt":[{"subitem_text_value":"Case Report"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Muroi, Hiroto","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Nakajima, Masanobu","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Kikuchi, Maiko","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Takahashi, Masakazu","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Shida, Yosuke","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Ihara, Keisuke","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Ito, Jun","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Yamaguchi, Satoru","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Sasaki, Kinro","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Kato, Hiroyuki","creatorNameLang":"en"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2019-02-06"}],"displaytype":"detail","filename":"DJMS-45-2-5.pdf","filesize":[{"value":"369.3 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"DJMS-45-2-Muroi-本文","url":"https://dmu.repo.nii.ac.jp/record/2117/files/DJMS-45-2-5.pdf"},"version_id":"b1f3e00f-61a3-4b09-bb4e-830633681eb9"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"malignant melanoma","subitem_subject_scheme":"Other"},{"subitem_subject":"esophagus","subitem_subject_scheme":"Other"},{"subitem_subject":"nivolumab","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Effectiveness of Anti-PD-1 Antibody Monotherapy for the Primary Malignant Melanoma of the Esophagus： A Case Report","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Effectiveness of Anti-PD-1 Antibody Monotherapy for the Primary Malignant Melanoma of the Esophagus： A Case Report"}]},"item_type_id":"10001","owner":"14","path":["156"],"publish_date":"2019-02-06","publish_status":"0","recid":"2117","relation_version_is_last":true,"title":["Effectiveness of Anti-PD-1 Antibody Monotherapy for the Primary Malignant Melanoma of the Esophagus： A Case Report"],"weko_creator_id":"14","weko_shared_id":-1},"updated":"2023-06-20T15:36:10.921072+00:00"}