@article{oai:dmu.repo.nii.ac.jp:00000213,
 author = {Nemoto, Kazuhiro},
 issue = {1},
 journal = {Dokkyo journal of medical sciences},
 month = {Mar},
 note = {Cytocidal effects of anti-cancer drugs such as cisplatin, 5-fluorouracil (5-FU), and actinomycin D on various cell lines were investigated using Alamar Blue. Actinomycin D, cisplatin and 5-FU showed significant cytocidal effects at 1μg/ml, 10μg/ml and 50μg/ml respectively, on cultured cells after 24 h incubation at 37℃. The cytocidal effects increased at a low cell density but reduced at a high cell density in various cell lines. The expression level of one of the ribosomal proteins, nbl (S3a), was measured by northern blot analysis and real time-polymerase chain reaction. The relationship between the nbl mRNA level and drug effects was then investigated for 8 rat and 10 human cell lines. An inverse correlation between chemosensitivity and nbl mRNA level was observed in both rat and human cell lines., 原著, Original},
 pages = {7--16},
 title = {Studies on Relationship between nbl (S3a) mRNA Levels, Cell Density, and Chemosensitivity in Various Rat and Human Cell Lines},
 volume = {31},
 year = {2004}
}