@article{oai:dmu.repo.nii.ac.jp:00002242,
 author = {Arai, Ryo and Ito, Hiroshi and Uchida, Nobuhiko and Shimizu, Yuka and Koike, Ryosuke and Nakamura, Yusuke and Masawa, Meitetsu and Okutomi, Tomoko and Okutomi, Hiroaki and Morita, Hiroko and Soda, Sayo and Yokoyama, Tatsuya and Watanabe, Taiji and Shiobara, Taichi and Ikeda, Naoya and Miyoshi, Masaaki and Chibana, Kazuyuki and Takemasa, Akihiro and Shimizu, Yasuo},
 issue = {3},
 journal = {Dokkyo Journal of Medical Sciences},
 month = {Oct},
 note = {This study investigated the difference of measured values between two types of analyzer over a wider range of fractional exhaled nitric oxide （FeNO） levels than in previous reports because some asthma patients have high FeNO levels. The equation for conversion of measured FeNO levels between the two analyzers was also determined.
Methods：Patients underwent assessment of FeNO for the diagnosis and management of asthma or for differential diagnosis of cough, FeNO levels were measured sequentially using both a stationary analyzer（NOA280i®, Sievers Inc, USA） and a hand-held analyzer（NIOX MINO®, Aerocrine Inc, Sweden）.
  FeNO levels were measured in a total of 167 subjects. Regression analysis of the FeNO data showed a strong positive correlation between values obtained with the two analyzers （r＝0.938, p＜0.0001）, and the regression line was calculated as：FeNO （NOA280i®）×0.63＋3.79＝FeNO （NIOX MINO®）. The correlation between the two analyzers was strongest at low FeNO values and it decreased as the FeNO level increased ［FeNO （NOA280i®）£50 （r＝0.730, p＜0.0001） FeNO （NOA280i®） 50 to £100 （r＝0.641, p＜0.0001）, FeNO （NOA280i®）＞100 to £150 （r＝0.607, p＝0.0008）, and FeNO （NOA280i®）＞150 （r＝0.523, p＝0.0180）］. Bland-Altman plot analysis between the two analyzers was 0.167 （95％ confidence interval＝－0.038 to 0.357, suggesting a positive difference.
Some caution is needed because the correlation between the two analyzers is weaker when the FeNO level exceeds 150.},
 pages = {103--111},
 title = {Measurement of Fractional Exhaled Nitric Oxide with a Stationary Analyzer（NOA280i®）or Hand-held Analyzer（NIOX MINO®）Shows a Strong Correlation but Weaker Correlation at Higher Levels},
 volume = {46},
 year = {2019}
}