@article{oai:dmu.repo.nii.ac.jp:00002316, author = {渡邊, 崇 and 古郡, 規雄 and 下田, 和孝 and Watanabe, Takashi and Furukori, Norio and Shimoda, Kazutaka}, issue = {2}, journal = {Dokkyo Journal of Medical Sciences}, month = {Jul}, note = {父娘がともに注意欠如・多動症(attention-deficit/hyperactivity disorder;ADHD)を発症した2 症例を経験した.ADHDは児童思春期に診察される場合が多いが,成人後にも症状が残遺することもあり,慢性的な疾患であると考えられる.この症例報告では,家族間であっても,有効な治療薬において差異が認められた.このような家族間での差異を多面発現性と多遺伝子モデルに基づいて考察した., This is a case report of both of a father and his daughter who contracted attention deficit/ hyperactivity disorder;ADHD. Although the onset of ADHD is before the age of 12 years, the neurodevelopmental trajectory shows a various pattern in terms of clinical symptoms, comorbid disorders, social impairment. Some patients have persistence of ADHD-related symptoms and fulfill the complete ADHD criteria in adult, and the other patients, only in their childhood. Nevertheless, ADHD-related symptoms, together with relevant comorbid other psychiatric disorders can cause suffering as well. Recent genetic studies indicate many different genetic factors might be associated with ADHD. Occasionally there are several differences in main clinical symptoms, comorbid disorder, and drug treatment response in a family. These differences are interpreted by polygenic model.}, pages = {73--78}, title = {親子で注意欠如・多動症を発症した2 症例}, volume = {47}, year = {2020} }