{"created":"2023-06-20T14:25:13.758998+00:00","id":318,"links":{},"metadata":{"_buckets":{"deposit":"fdbbb9a8-3836-4784-8036-4b8a31f37f3e"},"_deposit":{"created_by":3,"id":"318","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"318"},"status":"published"},"_oai":{"id":"oai:dmu.repo.nii.ac.jp:00000318","sets":["81:33"]},"author_link":["1248"],"item_2_biblio_info_12":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2005-03-25","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1","bibliographicPageEnd":"12","bibliographicPageStart":"7","bibliographicVolumeNumber":"32","bibliographic_titles":[{"bibliographic_title":"Dokkyo journal of medical sciences"}]}]},"item_2_description_11":{"attribute_name":"抄録(英)","attribute_value_mlt":[{"subitem_description":"Trichilemmal tumors can be either benign and malignant skin tumors arising from the outer root sheath of the hair follicle. It remains unknown whether malignant trichilemmal tumors can be differentiated from squamous cell carcinoma (SCC). In order to differentiate malignant trichilemmal tumors from SCC, we studied cytokeratin-related protein and involucrin expression immunohistochemically. Twenty-three trichilemmal carcinomas (TLC), 4 malignant proliferating tricholemmal tumors (MPTT) and 25 SCCs were studied. All the skin biopsy specimens were subjected to staining with anti-cytokeratin and anti-involucrin antibodies immunohistochemically, and the expression of cytokeratins and involucrin were investigated. The occurrence rate of cytoketatin 1 positive staining in TLC was significantly less than that in SCC (P<0.05), while that of cytokeratin 19 positivity in SCC was significantly less than that in TLC (P<0.01). These results demonstrate that immunohistochemical staining with anti-cytokeratin 1 and anti-cytokeratin 19 antibodies is useful for the differential diagnosis of TLC and SCC.","subitem_description_type":"Other"}]},"item_2_description_8":{"attribute_name":"記事種別(日)","attribute_value_mlt":[{"subitem_description":"原著","subitem_description_type":"Other"}]},"item_2_description_9":{"attribute_name":"記事種別(英)","attribute_value_mlt":[{"subitem_description":"Original","subitem_description_type":"Other"}]},"item_2_source_id_1":{"attribute_name":"雑誌書誌ID","attribute_value_mlt":[{"subitem_source_identifier":"AA00629581","subitem_source_identifier_type":"NCID"}]},"item_2_source_id_19":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"03855023","subitem_source_identifier_type":"ISSN"}]},"item_2_text_7":{"attribute_name":"著者所属(英)","attribute_value_mlt":[{"subitem_text_language":"en","subitem_text_value":"Department of Dermatology, Dokkyo University School of Medicine"}]},"item_2_title_3":{"attribute_name":"論文名よみ","attribute_value_mlt":[{"subitem_title":"Immunohistochemical Study of Cytokeratin Related Protein Expression in Patients with Trichilemmal Tumors and Squamous Cell Carcinoma of the Skin"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Hama, Naoto","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"1248","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2017-05-24"}],"displaytype":"detail","filename":"KJ00004161884.pdf","filesize":[{"value":"1.2 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"KJ00004161884.pdf","url":"https://dmu.repo.nii.ac.jp/record/318/files/KJ00004161884.pdf"},"version_id":"f80c17a7-93eb-46a1-ba91-8fbaf157f92b"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"trichilemmal carcinoma","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"squamous cell carcinoma","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"cytokeratin","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"involucrin","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"immunohistochemistry","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Immunohistochemical Study of Cytokeratin Related Protein Expression in Patients with Trichilemmal Tumors and Squamous Cell Carcinoma of the Skin","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Immunohistochemical Study of Cytokeratin Related Protein Expression in Patients with Trichilemmal Tumors and Squamous Cell Carcinoma of the Skin","subitem_title_language":"en"}]},"item_type_id":"2","owner":"3","path":["33"],"pubdate":{"attribute_name":"公開日","attribute_value":"2017-05-24"},"publish_date":"2017-05-24","publish_status":"0","recid":"318","relation_version_is_last":true,"title":["Immunohistochemical Study of Cytokeratin Related Protein Expression in Patients with Trichilemmal Tumors and Squamous Cell Carcinoma of the Skin"],"weko_creator_id":"3","weko_shared_id":3},"updated":"2023-06-20T16:27:39.738131+00:00"}