@article{oai:dmu.repo.nii.ac.jp:00005120,
 author = {Ganbold, Tsengel and Nakagami, Yoshihiro and Imamura, Kensuke and Misu, Yosuke and Kumazawa, Mariko and Arakawa, Hiroaki and Ichikawa, Motoshi and Mitani, Kinuko and Ishida, Kazuyuki and Kano, Daisuke and Hosokawa, Shota and Kaji, Yasushi},
 issue = {1},
 journal = {Dokkyo Medical Journal},
 month = {Mar},
 note = {Background: The current study investigated the relationship between maximum standardized uptake values (SUVmax) on Fluorine-18 Fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) and the plasma cell proliferation percentage in the bone marrow as well as hematological and biochemical test results of patients with multiple myeloma (MM). Moreover, we identified if differences exist in parameters across different types of paraproteins and stages.
　Material and methods: Patients clinically and pathologically diagnosed with MM between 2012 and 2019 were selected from the database of the Dokkyo Medical University Hospital, Japan. Unsuitable patients were excluded from the current study to avoid false uptake. We examined 60 patients and hematological and biochemical tests were recorded and evaluated. The percentage of plasma cells in bone marrow aspiration samples was calculated. In PET/CT images, the SUVmax of the region of interest of the right posterior ilium (aspiration area) was measured. Relationships were examined using Spearman’s correlation coefficient, and differences were identified using the Kruskal-Wallis test with SPSS.
　Results: A positive correlation was observed between FDG uptake and the percentage of plasma cells (r = 0.672, P < 0.0001).
　Conclusion: Increased FDG uptake by bone marrow correlated with the percentage of plasma cells. Some
biochemical and hematological parameters were statistically different according to the stage and types of
paraproteins. PET/CT is suitable for evaluating the condition of a patient and the activity of the MM lesion.},
 pages = {63--71},
 title = {Relationship between Fluorine-18 Fluorodeoxyglucose PET/CT Uptake and the Plasma Cell Infiltration Rate in the Bone Marrow of Multiple Myeloma Patients},
 volume = {1},
 year = {2022}
}