{"created":"2023-06-20T14:29:07.104733+00:00","id":5124,"links":{},"metadata":{"_buckets":{"deposit":"45c00e2b-690f-4b67-a8ba-1a2fa1b24df6"},"_deposit":{"created_by":14,"id":"5124","owners":[14],"pid":{"revision_id":0,"type":"depid","value":"5124"},"status":"published"},"_oai":{"id":"oai:dmu.repo.nii.ac.jp:00005124","sets":["223:225"]},"author_link":["46694","46699","46698","46701","46702","46695","10463","2578","46700","46697","46703","46330","46696"],"item_10001_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2022-03","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1","bibliographicPageEnd":"48","bibliographicPageStart":"39","bibliographicVolumeNumber":"1","bibliographic_titles":[{"bibliographic_title":"Dokkyo Medical Journal"}]}]},"item_10001_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"　Background: There are pros and cons regarding the benefit of extended pelvic lymph node dissection (PLND) during surgery for prostate cancer (PCa). A randomized controlled trial failed to demonstrate any survival benefits, and the therapeutic role of PLND remains unclear. We evaluated early survival outcome using a propensity score (PS)-matched analysis.\n　Methods: Three hundred ninety-nine patients with intermediate- to high-risk PCa were enrolled. They were determined to have a lymph node (LN) invasion probability of greater than 7% on the established nomogram. The National Comprehensive Cancer Network classification was used as risk stratification. Biochemical recurrence (BCR)-free survival was compared between the two groups divided by the threshold of the LN yield set at 15.\n　Results: The mean LN yield was 23.7 and 3.4 in the sufficient (n = 217) and insufficient (n = 182) LN yield groups, respectively. In the unmatched cohort, the advantage of the 3-year BCR-free survival for sufficient LN yield remained at 10.0% (hazard ratio [HR] 0.68, 95% confidence interval [CI] 0.43-1.07; p = 0.098). In the PS-matched cohort with 133 patients in each group, the difference in the 3-year BCR-free survival rate widened to 15.8% (HR 0.54, 95% CI 0.31-0.93; p = 0.027). A Cox regression multivariate analysis performed on the model with postoperative pathological factors showed an independent predictive value of LN yield.\n　Conclusions: The results demonstrate the therapeutic role of PLND in intermediate- to high-risk PCa. The benefit of PLND depends on the surgeon adhering to the template and removing a sufficient number of LNs in patients with an optimal risk-range.","subitem_description_type":"Abstract"}]},"item_10001_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Dokkyo Medical Society"}]},"item_10001_relation_14":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"10.51040/dkmj.1.1_39","subitem_relation_type_select":"DOI"}}]},"item_10001_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"2436-5211","subitem_source_identifier_type":"ISSN"}]},"item_10001_text_24":{"attribute_name":"著者所属","attribute_value_mlt":[{"subitem_text_value":"Department of Urology, Dokkyo Medical University"},{"subitem_text_value":"Department of Urology, Dokkyo Medical University"},{"subitem_text_value":"Department of Urology, Dokkyo Medical University"},{"subitem_text_value":"Department of Urology, Dokkyo Medical University"},{"subitem_text_value":"Department of Urology, Dokkyo Medical University"},{"subitem_text_value":"Department of Urology, Dokkyo Medical University"},{"subitem_text_value":"Department of Urology, Dokkyo Medical University"},{"subitem_text_value":"Department of Urology, Dokkyo Medical University"},{"subitem_text_value":"Department of Urology, Dokkyo Medical University"},{"subitem_text_value":"Department of Urology, Dokkyo Medical University"},{"subitem_text_value":"Department of Urology, Dokkyo Medical University"},{"subitem_text_value":"Department of Radiology, Dokkyo Medical University"},{"subitem_text_value":"Department of Diagnostic Pathology, Dokkyo Medical University"},{"subitem_text_value":"Department of Urology, Dokkyo Medical University"}]},"item_10001_text_33":{"attribute_name":"記事種別","attribute_value_mlt":[{"subitem_text_value":"Original"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Yashi, Masahiro","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Fuchizawa, Hirotaka","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Yokoyama, Megumi","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Okazaki, Akihito","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Nakamura, Gaku","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Kokubun, Hidetoshi","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Uematsu, Toshitaka","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Suzuki, Issei","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Sakamoto, Kazumasa","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Tokura, Yuumi","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Kijima, Toshiki","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Kaji, Yasushi","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Ishida, Kazuyuki","creatorNameLang":"en"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2022-04-27"}],"displaytype":"detail","filename":"DKMJ-1-1-8.pdf","filesize":[{"value":"405.6 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"DKMJ-1-1-Yashi-Fulltext","url":"https://dmu.repo.nii.ac.jp/record/5124/files/DKMJ-1-1-8.pdf"},"version_id":"2d6607d2-801e-4c65-a33c-71f3d527800f"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"biochemical recurrence-free survival","subitem_subject_scheme":"Other"},{"subitem_subject":"extended pelvic lymph node dissection","subitem_subject_scheme":"Other"},{"subitem_subject":"high-risk prostate cancer","subitem_subject_scheme":"Other"},{"subitem_subject":"intermediate-risk prostate cancer","subitem_subject_scheme":"Other"},{"subitem_subject":"propensity score-matched analysis","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Extended Pelvic Lymph Node Dissection during Robotic Prostate Surgery for Intermediate- to High-risk Prostate Cancer: A Propensity Score-matched Analysis for Biochemical Recurrence-free Survival","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Extended Pelvic Lymph Node Dissection during Robotic Prostate Surgery for Intermediate- to High-risk Prostate Cancer: A Propensity Score-matched Analysis for Biochemical Recurrence-free Survival"}]},"item_type_id":"10001","owner":"14","path":["225"],"publish_date":"2022-04-27","publish_status":"0","recid":"5124","relation_version_is_last":true,"title":["Extended Pelvic Lymph Node Dissection during Robotic Prostate Surgery for Intermediate- to High-risk Prostate Cancer: A Propensity Score-matched Analysis for Biochemical Recurrence-free Survival"],"weko_creator_id":"14","weko_shared_id":-1},"updated":"2023-06-20T14:45:15.936984+00:00"}