@article{oai:dmu.repo.nii.ac.jp:00005262, author = {Miyamoto, Masayuki and Miyamoto, Tomoyuki}, issue = {3}, journal = {Dokkyo Medical Journal}, month = {Sep}, note = {Polysomnography (PSG) is necessary for the diagnosis of REM sleep behavior disorder (RBD) according to the diagnostic criteria of the International Classification of Sleep Disorders, 2nd edition. We administered the REM sleep behavior disorder screening questionnaire-Japanese version (RBDSQ-J) to patients admitted to the hospital for PSG due to suspected sleep disorders and evaluated the background factors in patients with suspected RBD. We analyzed data from 261 out of 269 consecutive patients who were administered the RBDSQ-J and underwent PSG. Probable RBD was defined as a total RBDSQ-J score of ≥ 5. Sixty-six of the 261 patients (25.3%) had a total RBDSQ-J score of ≥ 5. Among the 66 patients, 10 (15.2%) had idiopathic or isolated RBD, 1 (1.5%) had secondary RBD with multiple system atrophy, and 55 (83.3%) did not have RBD. Among patients aged 50 years or older, all patients (n = 11) had RBD, whereas among those aged less than 50 years, none had RBD. The background factor in patients with false positive results was mainly obstructive sleep apnea syndrome (OSAS), whereas among young patients, the factors other than OSAS included narcolepsy, migraine, psychological disorders (such as PTSD, depression, or schizophrenia), and complications of central neurological disorders (such as sequelae of brainstem infarction or limbic encephalitis). RBDSQ-J is useful to screen for idiopathic/isolated RBD-associated synucleinopathies among middle-aged and elderly people aged ≥ 50 years, but among young patients and those with positive result of RBDSQ-J, various background factors may be present and the results should be interpreted with caution.}, pages = {218--225}, title = {Background Factors in the Interpretation of the Results of REM Sleep Behavior Disorder Screening Questionnaire-Japanese Version}, volume = {1}, year = {2022} }