{"created":"2023-06-20T14:29:14.440585+00:00","id":5271,"links":{},"metadata":{"_buckets":{"deposit":"7410582f-5982-471d-9a9f-2841e7d79409"},"_deposit":{"created_by":14,"id":"5271","owners":[14],"pid":{"revision_id":0,"type":"depid","value":"5271"},"status":"published"},"_oai":{"id":"oai:dmu.repo.nii.ac.jp:00005271","sets":["81:234"]},"author_link":["10019","6973","10627","842","10549","4011","10550","3871","4017","47056"],"item_10001_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2022-12-25","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"2","bibliographicPageEnd":"106","bibliographicPageStart":"102","bibliographicVolumeNumber":"49","bibliographic_titles":[{"bibliographic_title":"Dokkyo Journal of Medical Sciences"}]}]},"item_10001_description_34":{"attribute_name":"要旨","attribute_value_mlt":[{"subitem_description":"　症例は9歳女児．発熱，特徴的皮疹，自己抗体などの検査所見から小児全身性エリテマトーデス（SLE）と診断した．入院時の尿所見は軽度蛋白尿（尿蛋白/クレアチニン比0.41g/gCr）のみで血尿や細胞性円柱はみられなかった．腎生検の結果はISN/RPS分類でclassⅢA＋Ⅴであり，重症ループス腎炎（LN）を有する高リスク群であった．ステロイドパルス2コースにミコフェノール酸モフェチルの併用で寛解導入を行い，治療経過は良好である．SLEでは尿検査異常がなし〜軽微で腎機能障害もないが，病理学的にLNが存在するsilent LNが知られている．重症LNは腎予後・生命予後に関わるため，LNの有無や重症度の把握，その結果に基づいた適切な寛解導入および維持療法が重要である．尿所見が軽微であっても積極的に腎生検による病理学的評価を行うべきである．","subitem_description_type":"Other"}]},"item_10001_description_35":{"attribute_name":"要旨(英)","attribute_value_mlt":[{"subitem_description":"　A nine-year-old girl was diagnosed with systemic lupus erythematosus based on characteristic skin findings and laboratory findings such as autoantibodies. Urinary analysis showed a urinary protein and creatinine ratio of 0.41 g/g and no hematuria or cellular casts were observed. Renal biopsy showed an International Society of Nephrology （ISN）/Renal Pathology Society （RPS） Class IIIA and V, indicating a high-risk group with severe lupus nephritis （LN）. She was treated with methylprednisolone pulse combined with mycophenolate mofetil as induction therapy. Silent LN, which is pathologically present without abnormal urinalysis, is known. Since severe LN is related to renal and life prognosis, it is important to understand the presence or absence of LN and its severity, in order to provide appropriate induction and maintenance therapy based on these results. Pathological evaluation by renal biopsy should be aggressively performed even if urinary findings are slightly abnormal.","subitem_description_type":"Other"}]},"item_10001_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"獨協医学会"}]},"item_10001_source_id_11":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AA00629581","subitem_source_identifier_type":"NCID"}]},"item_10001_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"03855023","subitem_source_identifier_type":"ISSN"}]},"item_10001_text_24":{"attribute_name":"著者所属","attribute_value_mlt":[{"subitem_text_value":"獨協医科大学医学部 小児科学"},{"subitem_text_value":"獨協医科大学医学部 小児科学"},{"subitem_text_value":"獨協医科大学医学部 小児科学"},{"subitem_text_value":"獨協医科大学医学部 小児科学"},{"subitem_text_value":"獨協医科大学医学部 小児科学"}]},"item_10001_text_25":{"attribute_name":"著者所属(英)","attribute_value_mlt":[{"subitem_text_language":"en","subitem_text_value":"Department of Pediatrics, Dokkyo Medical University"},{"subitem_text_language":"en","subitem_text_value":"Department of Pediatrics, Dokkyo Medical University"},{"subitem_text_language":"en","subitem_text_value":"Department of Pediatrics, Dokkyo Medical University"},{"subitem_text_language":"en","subitem_text_value":"Department of Dermatology, Dokkyo Medical University"},{"subitem_text_language":"en","subitem_text_value":"Department of Pediatrics, Dokkyo Medical University"}]},"item_10001_text_33":{"attribute_name":"記事種別","attribute_value_mlt":[{"subitem_text_value":"症例報告"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"藤田, 雄治"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"加納, 優治"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"鷹木, 雄飛"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"林, 周次郎"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"吉原, 重美"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Fujita, Yuji","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Kano, Yuji","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Takagi, Yuhi","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Hayashi, Shujiro","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Yoshihara, Shigemi","creatorNameLang":"en"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2023-01-17"}],"displaytype":"detail","filename":"DJMS-49-2-5.pdf","filesize":[{"value":"370.2 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"DJMS-49-2-藤田-本文","url":"https://dmu.repo.nii.ac.jp/record/5271/files/DJMS-49-2-5.pdf"},"version_id":"120f06de-68ef-4708-9c4c-804a3baf303c"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"全身性エリテマトーデス","subitem_subject_scheme":"Other"},{"subitem_subject":"ループス腎炎","subitem_subject_scheme":"Other"},{"subitem_subject":"ミコフェノール酸モフェチル","subitem_subject_scheme":"Other"},{"subitem_subject":"systemic lupus erythematosus","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"lupus nephritis","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"mycophenolate mofetil","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"尿所見が軽微であったが重症ループス腎炎（ⅢA＋Ⅴ型）を有した全身性エリテマトーデスの9歳女児","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"尿所見が軽微であったが重症ループス腎炎（ⅢA＋Ⅴ型）を有した全身性エリテマトーデスの9歳女児"},{"subitem_title":"Systemic Lupus Erythematosus with Severe Lupus Nephritis Class IIIA and V in a Pediatric Case with Slight Abnormal Urinary Findings","subitem_title_language":"en"}]},"item_type_id":"10001","owner":"14","path":["234"],"publish_date":"2023-01-17","publish_status":"0","recid":"5271","relation_version_is_last":true,"title":["尿所見が軽微であったが重症ループス腎炎（ⅢA＋Ⅴ型）を有した全身性エリテマトーデスの9歳女児"],"weko_creator_id":"14","weko_shared_id":-1},"updated":"2023-06-20T14:44:15.969873+00:00"}