{"created":"2023-06-20T14:29:18.658248+00:00","id":5358,"links":{},"metadata":{"_buckets":{"deposit":"49de7bdb-0892-4ccb-8f28-a16e498fb815"},"_deposit":{"created_by":14,"id":"5358","owners":[14],"pid":{"revision_id":0,"type":"depid","value":"5358"},"status":"published"},"_oai":{"id":"oai:dmu.repo.nii.ac.jp:00005358","sets":["223:236"]},"author_link":["47280","47287","47276","47275","47286","47281","47282","47283","47284","47277","47285","47278","47288","47289","47279"],"item_10001_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2022-12","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"4","bibliographicPageEnd":"298","bibliographicPageStart":"292","bibliographicVolumeNumber":"1","bibliographic_titles":[{"bibliographic_title":"Dokkyo Medical Journal"}]}]},"item_10001_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Introduction: Embolus due to plaque rupture is a risk of cerebral infarction for carotid artery stenting (CAS). Female have been controversial as a risk factor for cardiovascular interventions in recent years. MMP-9 has been previously reported to be associated with acute ischemic stroke and to be a potential marker for arteriosclerosis.\n\nTherefore, this paper aimed to investigate the gender difference of embolic complications for CAS using MMP-9.\n\nMaterial and Methods: We analyzed 46 consecutive cases of CAS performed with distal balloon protection, including 34 males and 12 females. Serum levels of matrix metalloproteinase (MMP) -9 were measured before and after CAS. Embolic events were examined in Diffusion Weighted Imaging (DWI) on MRI the next day after CAS.\n\nResults: 13 cases (28.3%) had DWI-positive findings after CAS, and these results showed a significant gender difference (female 58.3% vs. male 17.6%, p < 0.05). Pre-CAS MMP-9 was significantly higher in females than in males (661.7 vs. 428.1 ng/ml, p < 0.05).\n\nPre-CAS MMP-9 tended to be higher in DWI-positive cases than DWI-negative cases with no significant difference (676.9 vs. 415.0 ng/ml, p = 0.051).\n\nConclusion: High serum MMP-9 in female have correlation with DWI positive findings after CAS. We suggest that high serum MMP-9 have a risk of cerebral infarction for CAS. Considering the results, CAS should be carefully performed, especially in female.","subitem_description_type":"Abstract"}]},"item_10001_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Dokkyo Medical Society"}]},"item_10001_relation_14":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"10.51040/dkmj.2022-015","subitem_relation_type_select":"DOI"}}]},"item_10001_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"2436-522X","subitem_source_identifier_type":"ISSN"}]},"item_10001_text_24":{"attribute_name":"著者所属","attribute_value_mlt":[{"subitem_text_value":"Department of Neurosurgery, Dokkyo Medical University Saitama Medical Center"},{"subitem_text_value":"Department of Neurosurgery, Dokkyo Medical University Saitama Medical Center"},{"subitem_text_value":"Department of Neurosurgery, Dokkyo Medical University Saitama Medical Center"},{"subitem_text_value":"Department of Neurosurgery, Dokkyo Medical University Saitama Medical Center"},{"subitem_text_value":"Department of Neurosurgery, Dokkyo Medical University Saitama Medical Center"},{"subitem_text_value":"Department of Neurosurgery, Dokkyo Medical University Saitama Medical Center"},{"subitem_text_value":"Department of Neurosurgery, Dokkyo Medical University Saitama Medical Center"},{"subitem_text_value":"Department of Neurosurgery, Dokkyo Medical University Saitama Medical Center"},{"subitem_text_value":"Department of Neurosurgery, Dokkyo Medical University Saitama Medical Center"},{"subitem_text_value":"Department of Neurosurgery, Dokkyo Medical University Saitama Medical Center"},{"subitem_text_value":"Department of Neurosurgery, Dokkyo Medical University Saitama Medical Center"},{"subitem_text_value":"Department of Neurosurgery, Dokkyo Medical University Saitama Medical Center"},{"subitem_text_value":"Department of Neurosurgery, Dokkyo Medical University Saitama Medical Center"},{"subitem_text_value":"Department of Neurosurgery, Dokkyo Medical University Saitama Medical Center"},{"subitem_text_value":"Department of Neurosurgery, Dokkyo Medical University Saitama Medical Center"}]},"item_10001_text_33":{"attribute_name":"記事種別","attribute_value_mlt":[{"subitem_text_value":"Original"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Tanaka, Yoshihiro","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Takigawa, Tomoji","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Synmyo, Kei","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Anazawa, Toru","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Matsumoto, Yoshiyuki","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Fujii, Yoshiko","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Kanaya, Takahiro","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Nariai, Yasuhiko","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Sugiura, Yoshiki","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Kawamura, Yosuke","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Suzuki, Ryotaro","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Takano, Issei","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Hyodo, Akio","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Nagaishi, Masaya","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Suzuki, Kensuke","creatorNameLang":"en"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2023-03-27"}],"displaytype":"detail","filename":"DKMJ-1-4-4.pdf","filesize":[{"value":"135.2 kB"}],"format":"application/pdf","licensetype":"license_11","mimetype":"application/pdf","url":{"label":"DKMJ-1-4-Tanaka-Fulltext","url":"https://dmu.repo.nii.ac.jp/record/5358/files/DKMJ-1-4-4.pdf"},"version_id":"cc638695-a445-4e00-9235-e06283d70ad7"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"MMP-9","subitem_subject_scheme":"Other"},{"subitem_subject":"DWI-positive findings","subitem_subject_scheme":"Other"},{"subitem_subject":"female","subitem_subject_scheme":"Other"},{"subitem_subject":"CAS","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Serum MMP-9 in Females Have Higher Correlation with DWI-Positive Findings for Carotid Artery Stenting than in Males","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Serum MMP-9 in Females Have Higher Correlation with DWI-Positive Findings for Carotid Artery Stenting than in Males"}]},"item_type_id":"10001","owner":"14","path":["236"],"publish_date":"2023-03-27","publish_status":"0","recid":"5358","relation_version_is_last":true,"title":["Serum MMP-9 in Females Have Higher Correlation with DWI-Positive Findings for Carotid Artery Stenting than in Males"],"weko_creator_id":"14","weko_shared_id":-1},"updated":"2023-06-20T14:41:33.791117+00:00"}