@article{oai:dmu.repo.nii.ac.jp:00005364, author = {Morinaga, Yusuke and Kino, Hiroyoshi and Tanaka, Shuho and Miyamoto, Hidetaka and Akutsu, Hiroyoshi}, issue = {4}, journal = {Dokkyo Medical Journal}, month = {Dec}, note = {The differential diagnoses of cystic epithelial masses in the sellar and parasellar regions, when based on clinical findings, imaging, and even histopathological examination, can be challenging. Considerable evidence in the literature supports the existence of a common ectodermal origin of selected sellar and suprasellar cysts, which may account for the overlap of radiological features and pathological transitional states observed among these lesions. Here, we describe a case of suprasellar Rathke's cleft cyst (RCC) mimicking a dermoid cyst, which after successful removal by endoscopic endonasal surgery (EES) by an experienced team of neurosurgeons and otolaryngologists achieved a good clinical outcome. A 30-year-old male was referred with chief complaints of left-sided loss of vision and headache. Magnetic resonance imaging findings indicated possible diagnoses as RCC, craniopharyngioma, or dermoid cyst because the cyst partly contained fluid with a lipid signal. The cyst was resected en-bloc with EES, and the histopathological diagnosis was RCC. RCCs may contain lipid components within the cyst, presumed to be cholesterin crystals due to chronic inflammation. In preoperative imaging of suprasellar cystic lesions, the presence of lipid components in the cyst may not indicate dermoid cyst, and care should be taken to differentiate it from RCC or craniopharyngioma.}, pages = {344--350}, title = {Endoscopic Endonasal Surgery for Suprasellar Rathke's Cleft Cyst Mimicking a Dermoid Cyst}, volume = {1}, year = {2022} }