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Randomized Controlled Trial on the Necessity of Chemical Cleaning as Preoperative Preparation for Colorectal Cancer Surgery
https://dmu.repo.nii.ac.jp/records/612
https://dmu.repo.nii.ac.jp/records/612063df2fb-98b8-43f9-8180-33dcecab68da
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
KJ00005058716.pdf (629.8 kB)
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| Item type | [ELS]学術雑誌論文 / Journal Article(1) | |||||||
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| 公開日 | 2017-05-24 | |||||||
| タイトル | ||||||||
| タイトル | Randomized Controlled Trial on the Necessity of Chemical Cleaning as Preoperative Preparation for Colorectal Cancer Surgery | |||||||
| 言語 | en | |||||||
| 言語 | ||||||||
| 言語 | eng | |||||||
| キーワード | ||||||||
| 言語 | en | |||||||
| 主題 | Surgical site infection | |||||||
| キーワード | ||||||||
| 言語 | en | |||||||
| 主題 | Chemical preparation | |||||||
| キーワード | ||||||||
| 言語 | en | |||||||
| 主題 | Mechanical preparation | |||||||
| キーワード | ||||||||
| 言語 | en | |||||||
| 主題 | Kanamycin | |||||||
| 資源タイプ | ||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||
| 資源タイプ | journal article | |||||||
| 雑誌書誌ID | ||||||||
| 収録物識別子 | AA00629581 | |||||||
| 論文名よみ | ||||||||
| タイトル | Randomized Controlled Trial on the Necessity of Chemical Cleaning as Preoperative Preparation for Colorectal Cancer Surgery | |||||||
| 著者 |
Horie, Toru
× Horie, Toru
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| 著者所属(英) | ||||||||
| en | ||||||||
| Department of Gastroenterological Surgery, Dokkyo Medical University | ||||||||
| 記事種別(日) | ||||||||
| 内容記述タイプ | Other | |||||||
| 内容記述 | 原著 | |||||||
| 記事種別(英) | ||||||||
| 内容記述タイプ | Other | |||||||
| 内容記述 | Original | |||||||
| 抄録(英) | ||||||||
| 内容記述タイプ | Other | |||||||
| 内容記述 | The use of preoperative oral antibiotics for the preparation of elective colorectal surgery remains controversial. We examined the necessity of chemical preparation using oral antibiotics compared with mechanical preparation, to achieve the further reduction of infection rates in colorectal resection. Consecutive 91 patients were included in this prospective clinical trial of colon preparation. 45 patients received mechanical preparation alone with the polyethylene glycol lavage solution (group A), while 46 patients received mechanical preparation and chemical bowel preparation with 1.5g Kanamycin for 3 days orally before surgery (group B). Cefotiam hydrochloride was administered for 3 consecutive days after surgery in both groups. Specimens for culture were obtained pre-, intra- and post-operatively. In the specimens of intraoperative colonic mucosal swabs, Escherichia coli (E. coli) was significantly less cultured in group B than in group A. Postoperative diarrhea was observed in 7 patients of group A (15.5%) and in 20 patients of group B (43.5%) (p<0.05). The surgical site infection (SSI) rate was 20.0% in group A and 36.9% in group B (p=0.1041). Although there was no significant difference, SSI rate tended to be higher in group B than in group A. In conclusion, chemical preparation with oral intake of 1,500mg Kanamycin for 3 days before surgery did not add any advantages to mechanical preparation and is considered unnecessary to perform colorectal surgery. | |||||||
| 書誌情報 |
Dokkyo journal of medical sciences 巻 34, 号 3, p. 205-212, 発行日 2007-10-01 |
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| ISSN | ||||||||
| 収録物識別子タイプ | ISSN | |||||||
| 収録物識別子 | 03855023 | |||||||
