{"created":"2023-06-20T14:25:29.523541+00:00","id":641,"links":{},"metadata":{"_buckets":{"deposit":"3fd4c201-a212-4c31-9a69-c33ce6ec936b"},"_deposit":{"created_by":3,"id":"641","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"641"},"status":"published"},"_oai":{"id":"oai:dmu.repo.nii.ac.jp:00000641","sets":["81:45"]},"author_link":["2617"],"item_2_biblio_info_12":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2008-03-01","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1","bibliographicPageEnd":"12","bibliographicPageStart":"7","bibliographicVolumeNumber":"35","bibliographic_titles":[{"bibliographic_title":"Dokkyo journal of medical sciences"}]}]},"item_2_description_11":{"attribute_name":"抄録(英)","attribute_value_mlt":[{"subitem_description":"The number of patients with childhood obesity is increasing worldwide. The age of adiposity rebound (AR), the age when body mass starts to rise after transient decrease after birth, is thought to have a predictive value of obesity in adulthood. In order to elucidate whether the early gain of weight is related to the future occurrence of metabolic syndrome, the author examined the relationship between the time of AR and the prevalence of children having atherogenic small dense LDL (SDLDL) in serum at 12 years of age in Fujioka town in Japan. A total of 215 children (114 boys and 101 girls) who were born between 1995 and 1996 have been enrolled in this study as a prospective cohort. Annual measurements of body-mass index (BMI) from 4 months to 12 years were carried out. We defined the age of AR as the age when the lowest BMI occurred during this period. At 12 years of age, serum concentrations of lipids including of SDLDL and lipoproteins were measured. As results children who exhibited an earlier AR had the higher BMI value at 12 years of age (p<0.01) in both sexes. The prevalence of SDLDL decreased progressively from 15.0% in children in whom AR occurred before the age of 4 years to 0% in those in whom AR occurred after 6 years. Furthermore, the earlier AR was associated with elevated triglyceride (p<0.05) and apolipoprotein B (p<0.01) levels and decreased HDL-cholesterol levels (p<0.05). In conclusion the present longitudinal population-based study indicates that children who exhibit AR at a younger age seem to be predisposed towards the future development of metabolic syndrome. Thus, it is possible to identify high-risk children with metabolic syndrome prospectively by measuring early adiposity rebound.","subitem_description_type":"Other"}]},"item_2_description_8":{"attribute_name":"記事種別(日)","attribute_value_mlt":[{"subitem_description":"原著","subitem_description_type":"Other"}]},"item_2_description_9":{"attribute_name":"記事種別(英)","attribute_value_mlt":[{"subitem_description":"Original","subitem_description_type":"Other"}]},"item_2_source_id_1":{"attribute_name":"雑誌書誌ID","attribute_value_mlt":[{"subitem_source_identifier":"AA00629581"}]},"item_2_source_id_19":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"03855023","subitem_source_identifier_type":"ISSN"}]},"item_2_text_7":{"attribute_name":"著者所属(英)","attribute_value_mlt":[{"subitem_text_language":"en","subitem_text_value":"Department of Pediatrics, Dokkyo Medical University"}]},"item_2_title_3":{"attribute_name":"論文名よみ","attribute_value_mlt":[{"subitem_title":"Relation of Adiposity Rebound age to Serum Small Dense Low-density Lipoprotein in Young Childhood"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Yamazaki, Yuzuru","creatorNameLang":"en"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2017-05-24"}],"displaytype":"detail","filename":"KJ00005058745.pdf","filesize":[{"value":"588.0 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"KJ00005058745.pdf","url":"https://dmu.repo.nii.ac.jp/record/641/files/KJ00005058745.pdf"},"version_id":"4cc7a614-f792-4cb2-8815-a3c8e75a7bc2"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"body-mass index","subitem_subject_language":"en"},{"subitem_subject":"adiposity rebound","subitem_subject_language":"en"},{"subitem_subject":"obesity","subitem_subject_language":"en"},{"subitem_subject":"small dense LDL","subitem_subject_language":"en"},{"subitem_subject":"metabolic syndrome","subitem_subject_language":"en"},{"subitem_subject":"insulin resistance","subitem_subject_language":"en"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Relation of Adiposity Rebound age to Serum Small Dense Low-density Lipoprotein in Young Childhood","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Relation of Adiposity Rebound age to Serum Small Dense Low-density Lipoprotein in Young Childhood","subitem_title_language":"en"}]},"item_type_id":"2","owner":"3","path":["45"],"pubdate":{"attribute_name":"公開日","attribute_value":"2017-05-24"},"publish_date":"2017-05-24","publish_status":"0","recid":"641","relation_version_is_last":true,"title":["Relation of Adiposity Rebound age to Serum Small Dense Low-density Lipoprotein in Young Childhood"],"weko_creator_id":"3","weko_shared_id":3},"updated":"2023-06-20T16:12:15.692654+00:00"}