@article{oai:dmu.repo.nii.ac.jp:00000776, author = {中野, 亜有子 and 鈴木, 國弘 and 富澤, 敦子 and 平間, 記子 and 伴場, 信之 and 服部, 良之 and 笠井, 貴久男 and Ayuko, Nakano and Kunihiro, Suzuki and Atsuko, Tomizawa and Noriko, Hirama and Nobuyuki, Banba and Yoshiyuki, Hattori and Kikuo, Kasai}, issue = {2}, journal = {Dokkyo journal of medical sciences}, month = {Jul}, note = {[目的]バセドウ病 (GD) と破壊性甲状腺炎 (DT) の迅速鑑別法にはTSHレセプター抗体の有無,甲状腺エコー検査,遊離T3/T4 (FT3/FT4),総T3/T4比 (T3/T4),総ALP (T-ALP),甲状腺血流が有用とされている.そのうち最も鋭敏な指標となりうる項目を検討した.[方法]2007年から未治療で当科を受診したGD:15名,無痛性甲状腺炎(PT):8名,亜急性甲状腺炎( SAT):10名( DT:18名) を対象として,FT3/FT4,T3/T4,T-ALP,上甲状腺動脈平均血流速度( mean velocity STA) を測定した.[結果]年齢:GD51.2± 18.8歳,DT49.3±21.0歳,FT3/FT4:GD3.3±1.0,DT2.9±1.9,T3/T4:GD15.9±4.7,DT15.2± 3.3,T-ALP( U/l):GD431.3 ±196.6,DT299.1±163.2,mean velocitySTA( cm/s):GD65.0±8.7,DT41.0± 7.0,(P < 0.0001).[結論]今回の検討ではmean velocity STA がGD とDT の鑑別に最も有用であった., It is important to make a rapid differentialdiagnosis of Graves'Diseases (GD) and Destructive Thyroiditis(DT). However, it is often difficult to make a distinctionwithout measurement of radioactive iodine uptake(RAIU). Instead of measurement of RAIU, measuringFreeT3/FT4ratio (FT3/FT4), totalT3/T4ratio (T3/T4),total alkaline phosp hatase activity( T-ALP), blood flow inthe thyroid, is useful for differential diagnosis. We searchedfor the parameters is most sensitive parameter for rapiddifferential diagnosis.Patients and Methods:We investigated on 33 patientswith untreated hyperthyroidism (15 with GD and 18 withDT). When 33 patients were first seen in our hospital, wemeasured FT3/FT4, T3/T4, T-ALP, and mean velocity inthe superior thyroid arteries( STA).Results:In comparison between GD and DT, mean velocitySTA was significantly increased in patients with GD.In the group of GD, FT3/FT4 and T-ALP tend to be higherin patients with GD but without statistical significance.Conclusion:Mean velocity STA might be the most sensitiveparameter for rapid differential diagnosis of GD andDT., 症例報告}, pages = {105--108}, title = {バセドウ病と破壊性甲状腺炎の初診時における迅速鑑別法}, volume = {36}, year = {2009}, yomi = {ナカノ, アユコ and スズキ, クニヒロ and トミザワ, アツコ and ヒラマ, ノリコ and バンバ, ノブユキ and ハットリ, ヨシユキ and カサイ, キクオ} }