@article{oai:dmu.repo.nii.ac.jp:00000901, author = {百目木, 希実 and 門傳, 剛 and 松村, 美穂子 and 清水, 裕晶 and 池田, 志織 and 助川, 敦子 and 柳, 一徳 and 青木, 千枝 and 川越, 宣明 and 加瀬, 浩之 and 笠井, 貴久男 and Domeki, Nozomi and Monden, Tsuyoshi and Matsumura, Mihoko and Shimizu, Hiroaki and Ikeda, Shiori and Sukegawa, Atsuko and Yanagi, Kazunori and Aoki, Chie and Kawahoe, Yoshiaki and Kase, Hiroyuki and Kasai, Kikuo}, issue = {3}, journal = {Dokkyo journal of medical sciences}, month = {Oct}, note = {日本甲状腺学会から甲状腺クリーゼの診断基準が2008 年に発表された.2004 年4 月から2009 年3月に当院で臨床的に甲状腺クリーゼと診断,治療した20 症例を,その診断基準にあてはめ,治療と予後等について解析した.基礎疾患は全例バセドウ病だった.誘因として服用不規則や中断が9 例,感染症6 例,糖尿病性ケトアシドーシス3 例,情動ストレス2 例,脳血管障害1 例,外傷1 例だった.診断基準で確定診断例が15例,疑い例が1 例,除外症例が4 例だった.症状では中枢神経症状が疑い・確定診断例では11 例,脈拍130/分以上は12 例認められたが,除外例では認められなかった.治療としてはチアマゾールが全症例に使用されていた.ヨードは13 例,b ブロッカーは17 例,ステロイドは12 例の症例で使用されており全例救命できた.服用不規則や中断,感染症が誘引となりやすく,症状では中枢神経症状・脈拍が特にクリーゼの診断には重要と考えられた.後遺症を残す重症例は6 例で全て新診断基準によって確定診断された症例であり,新診断基準は予後への有用性も期待できると考えられた., The Japan Thyroid Association established diagnosticcriteria for thyroid crisis in 2008. Using these criteria, weanalyzed 20 cases clinically diagnosed as thyroid crisis andtreated in our hospital from April 2004 to March 2009. Allpatients had Basedow's disease at the basal disease. Thecauses were irregular compliance or interruption of treatment(9 cases), infection (6 cases), diabetic ketoacidosis (3cases), emotional stress( 2 cases), stroke( 1 case), and trauma(1 case). Fifteen cases were confirmed as thyroid crisis,1 case was suspected as thyroid crisis, and 4 cases were rejectedas thyroid crisis according to the diagnostic criteria.Central nervous symptoms were observed in 11 cases, andtachycardia (over 130 beats/min) in 12 cases in the definitiveand suspicious cases, although there were no centralnervous symptoms or tachycardia in the excluded cases.Thiamazole was administered to all patients. In addition, iodine(13 cases), b -blocker (17 cases), and corticosteroids(12 cases) were administered. All patients were recovered.Irregular internal use, stopping treatment, and infectionwere likely to induce thyroid crisis. In paticular, centralnervous symptoms and tachycardia were important factorsfor diagnosis. As 6 serious cases with aftereffect were diagnosedas definitive cases of thyroid crisis according to thenew criteria, these new criteria may be useful to predictthe prognosis., 原著, Original}, pages = {181--186}, title = {甲状腺クリーゼ20 例の治療と予後 : 甲状腺クリーゼ診断基準を用いた検討}, volume = {37}, year = {2010}, yomi = {ドウメキ, ノゾミ and モンデン, ツヨシ and マツムラ, ミホコ and シミズ, ヒロアキ and イケダ, シオリ and スケガワ, アツコ and ヤナギ, カズノリ and アオキ, チエ and カワゴエ, ヨシアキ and カセ, ヒロユキ and カサイ, キクオ} }