{"created":"2023-06-20T14:25:43.239883+00:00","id":921,"links":{},"metadata":{"_buckets":{"deposit":"2554eb88-228e-4997-aa34-b4ee92c25851"},"_deposit":{"created_by":3,"id":"921","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"921"},"status":"published"},"_oai":{"id":"oai:dmu.repo.nii.ac.jp:00000921","sets":["81:57"]},"author_link":["4093","4088","4090","4085","4080","4079","4074","4077","4078","4089","4092","4087","4076","4083","4128","4091","4075","4086","4082","4081"],"item_2_biblio_info_12":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2011-03-25","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1","bibliographicPageEnd":"47","bibliographicPageStart":"41","bibliographicVolumeNumber":"38","bibliographic_titles":[{"bibliographic_title":"Dokkyo journal of medical sciences"}]}]},"item_2_description_10":{"attribute_name":"抄録(日)","attribute_value_mlt":[{"subitem_description":"近年同定され,輸血後肝炎との関連が示唆されているTTV について,その母子感染の自然史と周産期における臨床的意義について後方視的,前方視的に検討した.HBV 及びHCV が検出されない妊婦(前方視的研究;NBCPW 群)におけるTTV DNA 陽性率は19.0%(37/195)であり,このうちsAST/sALT 値が110 U/L を超える例は皆無であった.HBV あるいはHCV キャリア妊婦(後方視的研究;BCCPW 群)ではTTV DNA 陽性率は25.0%(21/84)である.このうちsAST/sALT 値が110U/L を超える例は23.8%(5/21)に達し,この5 例はTTV 単独キャリアではなく,HBV 又はHCV との重複キャリアであった.NBCPW 群の出生児(14 名)におけるTTV DNA 陽転率は57.1%であり,このうちsAST/sALT 値が110 U/L を超えた例は無かった.BCCPW 群の出生児(21 名)におけるTTV DNA 陽転率は42.9%であり,このうちsAST/sALT 値が110 U/L を超えた児は2 名(22.2%)で,この2 名はHCV キャリアでもあった.TTV DNA 陽転化した総数17 名の出生児は全員生後18 ヶ月時点までTTV DNA 陽性が持続しており,脱キャリア化は認められていない.また,キャリア化児におけるTTV DNA 出現時期および哺育方法より経胎盤感染,経産道感染および経唾液感染は否定的であり,経母乳感染の可能性が強く示唆される結果であった.また,キャリア妊婦及びキャリア化児における肝機能異常は母子共々TTV 単独キャリアでは認められず,TTV 感染の周産期における臨床的インパクトは低いと思われる.","subitem_description_type":"Other"}]},"item_2_description_11":{"attribute_name":"抄録(英)","attribute_value_mlt":[{"subitem_description":"The natural history of mother-to-child transmission(MTCT) of the TT virus (TTV) was investigated retroandprospectively.Serum TTV DNA was detected in 37 out of the 195( 19.0%) pregnant women without both HBV and HCV in theirsera (NBCPW) and 21 out of the 84 (25.0 %) pregnantwomen with HBV and/or HCV (BCCPW). In the lattergroup, 5 out of the 21( 23.8%) TTV carrier pregnant womenshowed repeatedly sAST and/or sALT levels over110U/L, but none of the former group did.With informed consent (IC), 14 (NBCPW) and 21 (BCCPW)infants were followed from birth up to 18 months ofage by receiving tests for serum TTV DNA and levels ofsAST and sALT. Eight out of the 14 infants (57.1 %, NBCPW)and 9 out of the 21 infants( 42.9%, BCCPW) developedTTV carrier-state, and all of these 17 carrier infantsmaintained serum TTV DNA-positive through the followupperiods. No infants (NBCPW) showed elevated serumlevels (>110 U/L) of AST or ALT during the follow-upperiods, but 2 out of the 9 infants( 22.2%, BCCPW) showedsAST or sALT levels higher than 110 U/L, and these 2 infantswere found to be in HCV carrier-state.None of the infants developed a TTV-positive resultwithin 1 month after birth, and thereafter 11.8 % (2/17)developed carrier-state in 3 months, 47.1 % in 6 months,82.4 % in 12 months. These findings may exclude the intrauterineor trans-vaginal infection as a mode of TTVMTCT. On the other hand, all carrier infants with one exceptionwere raised by breast feeding, which was rich inTTV. Both carrier pregnant women and children, who wereneither HBV nor HCV carriers, showed no abnormal liverfunction through the follow-up periods.Thus, we conclude that TTV MTCT occurs highly, but itis not so significant practically.","subitem_description_type":"Other"}]},"item_2_description_8":{"attribute_name":"記事種別(日)","attribute_value_mlt":[{"subitem_description":"原著","subitem_description_type":"Other"}]},"item_2_description_9":{"attribute_name":"記事種別(英)","attribute_value_mlt":[{"subitem_description":"Original","subitem_description_type":"Other"}]},"item_2_source_id_1":{"attribute_name":"雑誌書誌ID","attribute_value_mlt":[{"subitem_source_identifier":"AA00629581"}]},"item_2_source_id_19":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"03855023","subitem_source_identifier_type":"ISSN"}]},"item_2_text_6":{"attribute_name":"著者所属(日)","attribute_value_mlt":[{"subitem_text_value":"獨協医科大学産科婦人科学"},{"subitem_text_value":"獨協医科大学産科婦人科学"},{"subitem_text_value":"獨協医科大学産科婦人科学"},{"subitem_text_value":"獨協医科大学産科婦人科学"},{"subitem_text_value":"獨協医科大学産科婦人科学"},{"subitem_text_value":"獨協医科大学産科婦人科学"},{"subitem_text_value":"獨協医科大学産科婦人科学"},{"subitem_text_value":"獨協医科大学産科婦人科学"},{"subitem_text_value":"獨協医科大学産科婦人科学"},{"subitem_text_value":"獨協医科大学産科婦人科学"}]},"item_2_text_7":{"attribute_name":"著者所属(英)","attribute_value_mlt":[{"subitem_text_language":"en","subitem_text_value":"Department of Obstetrics and Gynecology, Dokkyo Medical University"},{"subitem_text_language":"en","subitem_text_value":"Department of Obstetrics and Gynecology, Dokkyo Medical University"},{"subitem_text_language":"en","subitem_text_value":"Department of Obstetrics and Gynecology, Dokkyo Medical University"},{"subitem_text_language":"en","subitem_text_value":"Department of Obstetrics and Gynecology, Dokkyo Medical University"},{"subitem_text_language":"en","subitem_text_value":"Department of Obstetrics and Gynecology, Dokkyo Medical University"},{"subitem_text_language":"en","subitem_text_value":"Department of Obstetrics and Gynecology, Dokkyo Medical University"},{"subitem_text_language":"en","subitem_text_value":"Department of Obstetrics and Gynecology, Dokkyo Medical University"},{"subitem_text_language":"en","subitem_text_value":"Department of Obstetrics and Gynecology, Dokkyo Medical University"},{"subitem_text_language":"en","subitem_text_value":"Department of Obstetrics and Gynecology, Dokkyo Medical University"},{"subitem_text_language":"en","subitem_text_value":"Department of Obstetrics and Gynecology, Dokkyo Medical University"}]},"item_2_title_3":{"attribute_name":"論文名よみ","attribute_value_mlt":[{"subitem_title":"TT ウイルス ボシ カンセン ノ コウホウシテキ, ゼンホウシテキ ケンキュウ : トクニ ボシ カンセン ヨウシキ ト シュウサンキ ニオケル リンショウテキ イギ ニツイテ"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"稲葉, 未知世"},{"creatorName":"イナバ, ミチヨ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"大島, 教子"},{"creatorName":"オオシマ, キョウコ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"林田, 志峯"},{"creatorName":"ハヤシダ, シホウ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"西川, 正能"},{"creatorName":"ニシカワ, マサヨシ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"岡嶋, 祐子"},{"creatorName":"オカジマ, ユウコ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"北澤, 正文"},{"creatorName":"キタザワ, マサフミ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"深澤, 一雄"},{"creatorName":"フカサワ, イチオ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"渡辺, 博"},{"creatorName":"ワタナベ, ヒロシ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"高見澤, 裕吉"},{"creatorName":"タカミザワ, ヒロヨシ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"稻葉, 憲之"},{"creatorName":"イナバ, ノリユキ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Inaba, Michiyo","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Oshima, Kyoko","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Hayashida, Shihou","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Nishikawa, Masayoshi","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Okajima, Yuko","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Kitazawa, Masafumi","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Fukasawa, Ichio","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Watanabe, Hiroshi","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Takamizawa, Hiroyoshi","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Inaba, Noriyuki","creatorNameLang":"en"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2017-05-24"}],"displaytype":"detail","filename":"KJ00006979480.pdf","filesize":[{"value":"320.9 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"KJ00006979480.pdf","url":"https://dmu.repo.nii.ac.jp/record/921/files/KJ00006979480.pdf"},"version_id":"d955ab19-2f69-420a-a55a-f6caa4d21e91"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"T T virus( TTV)"},{"subitem_subject":"mother-to-child transmission( MTCT)"},{"subitem_subject":"carrier-state"},{"subitem_subject":"breast-feeding"},{"subitem_subject":"hepato-pathogenicity"},{"subitem_subject":"TT virus (TTV)","subitem_subject_language":"en"},{"subitem_subject":"mother-to-child transmission (MTCT)","subitem_subject_language":"en"},{"subitem_subject":"carrier-state","subitem_subject_language":"en"},{"subitem_subject":"breast-feeding","subitem_subject_language":"en"},{"subitem_subject":"hepato-pathogenicity","subitem_subject_language":"en"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"TT ウイルス母子感染の後方視的,前方視的研究 : 特に母子感染様式と周産期における臨床的意義について","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"TT ウイルス母子感染の後方視的,前方視的研究 : 特に母子感染様式と周産期における臨床的意義について"},{"subitem_title":"Retro-and Prospective Studies on TT Virus Infection in the Offspring born from TT Virus Carrier Women:With Special Reference to TT Virus Infectious Modes and Liver Pathogenicity","subitem_title_language":"en"}]},"item_type_id":"2","owner":"3","path":["57"],"pubdate":{"attribute_name":"公開日","attribute_value":"2017-05-24"},"publish_date":"2017-05-24","publish_status":"0","recid":"921","relation_version_is_last":true,"title":["TT ウイルス母子感染の後方視的,前方視的研究 : 特に母子感染様式と周産期における臨床的意義について"],"weko_creator_id":"3","weko_shared_id":3},"updated":"2023-06-20T15:52:18.754616+00:00"}