{"_buckets": {"deposit": "96c46122-09ef-4a77-a465-16cc7e2398d1"}, "_deposit": {"created_by": 3, "id": "1062", "owners": [3], "pid": {"revision_id": 0, "type": "depid", "value": "1062"}, "status": "published"}, "_oai": {"id": "oai:dmu.repo.nii.ac.jp:00001062", "sets": ["63"]}, "author_link": ["5003", "5001", "5000", "4999", "5002", "5004"], "item_2_biblio_info_12": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2012-10-25", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "3", "bibliographicPageEnd": "207", "bibliographicPageStart": "201", "bibliographicVolumeNumber": "39", "bibliographic_titles": [{"bibliographic_title": "Dokkyo journal of medical sciences"}]}]}, "item_2_description_10": {"attribute_name": "抄録(日)", "attribute_value_mlt": [{"subitem_description": "胸腔鏡下肺生検にて病理組織学的に非特異性間質性肺炎 (nonspecific interstitial pneumonia:NSIP) と診断された18例( 特発性NSIP:7例,膠原病に伴うNSIP:11例) を,ステロイド治療の反応性によって2 群に分け,臨床上改善が得られた群をresponder,得られなかった群をnon-responder とし,2 群間の病理組織所見,呼吸機能,血液ガス,バイオマーカー,bronchoalveolar lavage fluid( BALF),胸部high-resolutionCT( HRCT) 所見の比較検討を行った.responder群は10例,non-responder群は8例であり,両群共に女性に多い傾向はあったが,平均年齢,PaO2 に有意差は認められなかった.病理組織所見では,non-responder群において組織学的により線維化が強い傾向があり,画像上reticulation 優位のパターンが8 例中4 例に認められた.また,non-responder 群における診断時のKL-6,SP-D は,responder 群と比較して高値を示していた.胸部CT においてconsolidation を示す部位はステロイドによる初期治療に反応する場合が多く,画像所見は治療反応規定因子として重要であると思われた.", "subitem_description_type": "Other"}]}, "item_2_description_11": {"attribute_name": "抄録(英)", "attribute_value_mlt": [{"subitem_description": "Eighteen patients of nonspecific interstitial pneumonia(NSIP) were evaluated retrospectively to know the predictivefactors for response to corticosteroid therapy. The diagnosiswas established based on lung biopsy performed byvideo-assisted thoracoscopic surgery. Early phase response(after 1 month) to therapy was determined by pretreatmentand post-treatment clinical (dyspnea), radiographic(chest HRCT), and physiologic (pulmonary function andblood gas analysis) scores (CRP). Ten (55.6 %) patientswere responders, 8( 44.4%) were non-responders. Patientswith cellular pattern ware more likely to respond comparedto patients with fibrosing pattern after treatment withprednisolone. The presence of advanced fibrosis was themost important factor influencing responsiveness to steroid.Consolidation pattern on HRCT indicated better response tosteroid whereas reticular pattern indicated poor response.", "subitem_description_type": "Other"}]}, "item_2_description_15": {"attribute_name": "表示順", "attribute_value_mlt": [{"subitem_description": "6", "subitem_description_type": "Other"}]}, "item_2_description_16": {"attribute_name": "アクセション番号", "attribute_value_mlt": [{"subitem_description": "KJ00008179019", "subitem_description_type": "Other"}]}, "item_2_description_8": {"attribute_name": "記事種別(日)", "attribute_value_mlt": [{"subitem_description": "原著", "subitem_description_type": "Other"}]}, "item_2_source_id_1": {"attribute_name": "雑誌書誌ID", "attribute_value_mlt": [{"subitem_source_identifier": "AA00629581", "subitem_source_identifier_type": "NCID"}]}, "item_2_source_id_19": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "03855023", "subitem_source_identifier_type": "ISSN"}]}, "item_2_text_6": {"attribute_name": "著者所属(日)", "attribute_value_mlt": [{"subitem_text_value": "獨協医科大学内科学(呼吸器・アレルギー)"}, {"subitem_text_value": "獨協医科大学内科学(呼吸器・アレルギー)"}, {"subitem_text_value": "獨協医科大学内科学(呼吸器・アレルギー)"}]}, "item_2_text_7": {"attribute_name": "著者所属(英)", "attribute_value_mlt": [{"subitem_text_language": "en", "subitem_text_value": "Department of Pulmonary Medicine and Clinical Immunology Dokkyo Medical University School of Medicine"}, {"subitem_text_language": "en", "subitem_text_value": "Department of Pulmonary Medicine and Clinical Immunology Dokkyo Medical University School of Medicine"}, {"subitem_text_language": "en", "subitem_text_value": "Department of Pulmonary Medicine and Clinical Immunology Dokkyo Medical University School of Medicine"}]}, "item_2_title_3": {"attribute_name": "論文名よみ", "attribute_value_mlt": [{"subitem_title": "Nonspecific Interstitial Pneumonia( NSIP) ニオケル ステロイド チリョウ ハンノウセイ キテイ インシ ノ ケントウ "}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "降籏, 友恵"}, {"creatorName": "フリハタ, トモエ", "creatorNameLang": "ja-Kana"}], "nameIdentifiers": [{"nameIdentifier": "4999", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "石井, 芳樹"}, {"creatorName": "イシイ, ヨシキ", "creatorNameLang": "ja-Kana"}], "nameIdentifiers": [{"nameIdentifier": "5000", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "福田, 健"}, {"creatorName": "フクダ, タケシ", "creatorNameLang": "ja-Kana"}], "nameIdentifiers": [{"nameIdentifier": "5001", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Furihata, Tomoe", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "5002", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Ishii, Yoshiki", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "5003", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Fukuda, Takeshi", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "5004", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2017-05-24"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "KJ00008179019.pdf", "filesize": [{"value": "952.5 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_free", "mimetype": "application/pdf", "size": 952500.0, "url": {"label": "KJ00008179019.pdf", "url": "https://dmu.repo.nii.ac.jp/record/1062/files/KJ00008179019.pdf"}, "version_id": "eda67b81-c7ad-48e7-b7ad-db3f4f714ee3"}]}, "item_keyword": {"attribute_name": "キーワード", "attribute_value_mlt": [{"subitem_subject": "nonspecific interstitial pneumonia", "subitem_subject_scheme": "Other"}, {"subitem_subject": "high-resolution CT", "subitem_subject_scheme": "Other"}, {"subitem_subject": "ステロイド", "subitem_subject_scheme": "Other"}, {"subitem_subject": "治療反応性規定因子", "subitem_subject_scheme": "Other"}, {"subitem_subject": "nonspecific interstitial pneumonia", "subitem_subject_language": "en", "subitem_subject_scheme": "Other"}, {"subitem_subject": "high-resolution CT", "subitem_subject_language": "en", "subitem_subject_scheme": "Other"}, {"subitem_subject": "steroid", "subitem_subject_language": "en", "subitem_subject_scheme": "Other"}, {"subitem_subject": "predictive factors", "subitem_subject_language": "en", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "jpn"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "journal article", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "Nonspecific Interstitial Pneumonia( NSIP) におけるステロイド治療反応性規定因子の検討", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "Nonspecific Interstitial Pneumonia( NSIP) におけるステロイド治療反応性規定因子の検討"}, {"subitem_title": "Predictive Factors for Response to Steroid Therapy in Patients with Nonspecific Interstitial Pneumonia", "subitem_title_language": "en"}]}, "item_type_id": "2", "owner": "3", "path": ["63"], "permalink_uri": "https://dmu.repo.nii.ac.jp/records/1062", "pubdate": {"attribute_name": "公開日", "attribute_value": "2017-05-24"}, "publish_date": "2017-05-24", "publish_status": "0", "recid": "1062", "relation": {}, "relation_version_is_last": true, "title": ["Nonspecific Interstitial Pneumonia( NSIP) におけるステロイド治療反応性規定因子の検討"], "weko_shared_id": 3}