| Item type |
[ELS]学術雑誌論文 / Journal Article(1) |
| 公開日 |
2017-05-24 |
| タイトル |
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タイトル |
Positive Therapeutic Response to Bevacizumab Plus Paclitaxel in a Patient with Advanced, Life-Threatening Breast Cancer and Carcinomatous Lymphangitis:a Subsequent Treatment Change to Hormone Therapy |
|
言語 |
en |
| 言語 |
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言語 |
eng |
| キーワード |
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言語 |
en |
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主題 |
breast cancer |
| キーワード |
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言語 |
en |
|
主題 |
bavacizumab |
| 資源タイプ |
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資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
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資源タイプ |
journal article |
| 雑誌書誌ID |
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収録物識別子 |
AA00629581 |
| 論文名よみ |
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タイトル |
Positive Therapeutic Response to Bevacizumab Plus Paclitaxel in a Patient with Advanced, Life-Threatening Breast Cancer and Carcinomatous Lymphangitis:a Subsequent Treatment Change to Hormone Therapy |
| 著者 |
Ishizuna, Kazuo
Ninomiya, Jun
Kojima, Makoto
Kawashima, Miho
Nishibayashi, Fumiko
Nozaki, Miwako
Yamagishi, Hidetsugu
Ueda, Yoshihiko
Oya, Masatoshi
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| 著者所属(英) |
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en |
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Breast Center, Dokkyo Medical University Koshigaya Hospital |
| 著者所属(英) |
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en |
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Ninomiya Hospital |
| 著者所属(英) |
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en |
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Breast Center, Dokkyo Medical University Koshigaya Hospital |
| 著者所属(英) |
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en |
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Department of Radiology, Dokkyo Medical University Kosigaya Hospital |
| 著者所属(英) |
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en |
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Department of Radiology, Dokkyo Medical University Kosigaya Hospital |
| 著者所属(英) |
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en |
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Department of Radiology, Dokkyo Medical University Kosigaya Hospital |
| 著者所属(英) |
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en |
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Department of Pathology, Dokkyo Medical University Kosigaya Hospital |
| 著者所属(英) |
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en |
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Department of Pathology, Dokkyo Medical University Kosigaya Hospital |
| 著者所属(英) |
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en |
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Breast Center, Dokkyo Medical University Koshigaya Hospital |
| 記事種別(英) |
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内容記述タイプ |
Other |
|
内容記述 |
Case Report |
| 抄録(英) |
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内容記述タイプ |
Other |
|
内容記述 |
We present a case of advanced, life-threatening breast cancer with carcinomatous lymphangitis treatedwith bevacizumab plus paclitaxel. A positive therapeutic response was achieved and the treatment was subsequentlychanged to hormone therapy.The patient was a 53-year-old postmenopausal woman with a non-contributory medical history. She presentedto a nearby hospital with chief complaints of continued exertional dyspnea and coughing since March2012. Physical findings included a palpable mass in the left breast, and the patient was referred and presentedto our hospital in May. Examinations at our hospital revealed left-sided breast cancer (estrogen receptorpositive, progesterone receptor positive, and no amplification of the human epidermal growth factorreceptor 2 by FISH). The patient had bone metastasis and carcinomatous lymphangitis (cT2N3cM1-stageIV). The condition was life threatening, and administration of bevacizumab plus weekly paclitaxel was initiatedwith the expectation of a high response rate. Coughing and dyspnea resolved two weeks later. CTscans were taken in August after the completion of 3 cycles and showed improvement in carcinomatouslymphangitis. No major side effects were observed due to bevacizumab plus weekly paclitaxel. When theCT scans were taken in December after the completion of 6 cycles, the primary lesion and lymph node metastaseswere reduced in size. In the lung field, there was no thickening of the interlobular septa or subpleuralinterstitium, and the findings of carcinomatous lymphangitis were improved. Thus, bevacizumab plus paclitaxelwere discontinued and the treatment was changed to oral letrozole (2.5 mg/day). The patient hasbeen followed up with no recurrence as of March 2013. |
| 書誌情報 |
Dokkyo journal of medical sciences
巻 40,
号 2,
p. 113-117,
発行日 2013-07-25
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| ISSN |
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収録物識別子タイプ |
ISSN |
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収録物識別子 |
03855023 |
KJ00008659039.pdf (301.7 kB)
