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  1. Dokkyo Journal of Medical Sciences
  2. 41(1) 2014

Low Dose Landiolol Combined with Catecholamine Can Decrease Heart Rate without Suppression of Cardiac Contraction after Cardiopulmonary Bypass

https://dmu.repo.nii.ac.jp/records/1169
https://dmu.repo.nii.ac.jp/records/1169
5a603723-75db-4dce-bd22-31a9fe03a932
名前 / ファイル ライセンス アクション
KJ00009214764.pdf KJ00009214764.pdf (659.1 kB)
Item type [ELS]学術雑誌論文 / Journal Article(1)
公開日 2017-05-24
タイトル
タイトル Low Dose Landiolol Combined with Catecholamine Can Decrease Heart Rate without Suppression of Cardiac Contraction after Cardiopulmonary Bypass
言語 en
言語
言語 eng
キーワード
言語 en
主題 Landiolol
キーワード
言語 en
主題 Catecholamine
キーワード
言語 en
主題 Heart Rate
キーワード
言語 en
主題 Cardiac Index
キーワード
言語 en
主題 Cardiopulmonary Bypass
資源タイプ
資源タイプ識別子 http://purl.org/coar/resource_type/c_6501
資源タイプ journal article
雑誌書誌ID
収録物識別子 AA00629581
論文名よみ
タイトル Low Dose Landiolol Combined with Catecholamine Can Decrease Heart Rate without Suppression of Cardiac Contraction after Cardiopulmonary Bypass
著者 Hamaguchi, Shinsuke

× Hamaguchi, Shinsuke

en Hamaguchi, Shinsuke

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Nagao, Masaru

× Nagao, Masaru

en Nagao, Masaru

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Takahashi, Yoshiyuki

× Takahashi, Yoshiyuki

en Takahashi, Yoshiyuki

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Ikeda, Tomohito

× Ikeda, Tomohito

en Ikeda, Tomohito

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Yamaguchi, Shigeki

× Yamaguchi, Shigeki

en Yamaguchi, Shigeki

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著者所属(英)
en
Department Of Anesthesia And Pain Medicine, Dokkyo Medical University School Of Medicine
著者所属(英)
en
Department Of Anesthesia And Pain Medicine, Dokkyo Medical University School Of Medicine
著者所属(英)
en
Department Of Anesthesia And Pain Medicine, Dokkyo Medical University School Of Medicine
著者所属(英)
en
Department Of Anesthesia And Pain Medicine, Dokkyo Medical University School Of Medicine
著者所属(英)
en
Department Of Anesthesia And Pain Medicine, Dokkyo Medical University School Of Medicine
記事種別(英)
内容記述タイプ Other
内容記述 Original
抄録(英)
内容記述タイプ Other
内容記述 Objective:Landiolol is a new ultra-short acting beta-adrenergic blocker that has potential for use in perioperative hemodynamic stabilization. The purpose of this study was to examine the effect of combined administration of landiolol and Catecholamine on regulation of heart rate in tachycardia after cardiopulmonary bypass.Design:The study was performed as a prospective controlled trial. Setting:A university hospital.Participants:The subjects were 30 of 64 patients with heart rate ≧ 115 bpm after weaning from cardiopulmonary bypass.Interventions:Fifteen of the patients (the landiolol group) were administered landiolol at a dose of 3-5 mg/kg/min without a decrease in the dose of Catecholamine. The other 15 patients( the control group)did not receive landiolol, but the Catecholamine dose of 1 m g/kg/min was decreased to reduce the heart rate.Results:Mean arterial pressure, cardiac index and heart rate were measured 5, 10 and 15 min after drug administration and postoperatively. Mean arterial pressure and cardiac index were unchanged after drug administration, but heart rate was significantly lower after 15 min and postoperatively in patients administered landiolol compared with those who did not receive landiolol. Conclusions:Combined administration of landiolol and Catecholamine is useful for stabilization of cardiovascular changes after cardiopulmonary bypass surgery.
書誌情報 Dokkyo journal of medical sciences

巻 41, 号 1, p. 27-33, 発行日 2014-03-25
ISSN
収録物識別子タイプ ISSN
収録物識別子 03855023
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