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Evaluation of Gastroesophageal Reflux and Gastroesophageal Reflux Disease with Esophageal Endoscopy and Histology in Children
https://dmu.repo.nii.ac.jp/records/1186
https://dmu.repo.nii.ac.jp/records/118615fee39e-26a4-491f-b096-baed7f3500b3
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
KJ00009350780.pdf (552.9 kB)
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| Item type | [ELS]学術雑誌論文 / Journal Article(1) | |||||||
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| 公開日 | 2017-05-24 | |||||||
| タイトル | ||||||||
| タイトル | Evaluation of Gastroesophageal Reflux and Gastroesophageal Reflux Disease with Esophageal Endoscopy and Histology in Children | |||||||
| 言語 | en | |||||||
| 言語 | ||||||||
| 言語 | eng | |||||||
| キーワード | ||||||||
| 言語 | en | |||||||
| 主題 | Gastroesophageal Reflux( Ger) | |||||||
| キーワード | ||||||||
| 言語 | en | |||||||
| 主題 | Gastroesophageal Reflux Disease( Gerd) | |||||||
| キーワード | ||||||||
| 言語 | en | |||||||
| 主題 | Endoscopy | |||||||
| キーワード | ||||||||
| 言語 | en | |||||||
| 主題 | Esophageal Histology | |||||||
| 資源タイプ | ||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||
| 資源タイプ | journal article | |||||||
| 雑誌書誌ID | ||||||||
| 収録物識別子 | AA00629581 | |||||||
| 論文名よみ | ||||||||
| タイトル | Evaluation of Gastroesophageal Reflux and Gastroesophageal Reflux Disease with Esophageal Endoscopy and Histology in Children | |||||||
| 著者 |
Fujino, Junko
× Fujino, Junko
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| 著者所属(英) | ||||||||
| en | ||||||||
| Department Of Pediatric Surgery, Dokkyo Medical University Koshigaya Hospital | ||||||||
| 記事種別(英) | ||||||||
| 内容記述タイプ | Other | |||||||
| 内容記述 | Original | |||||||
| 抄録(英) | ||||||||
| 内容記述タイプ | Other | |||||||
| 内容記述 | Objectives:The roles of esophageal endoscopy and mucosal biopsy in making diagnoses of gastroesophageal reflux( GER) and gastroesophageal reflux disease( GERD) were retrospectively examined in children.Methods:Thirty-four patients, whose ages ranged from 1 month to 18 years (median, 4 years), underwent diagnostic evaluation of GER/GERD. Group I patients( n=5) had symptoms suggesting GER, but had no underlying abnormalities. Group II patients( n=23) had chronic symptoms suggesting GERD and underlying abnormalities, neurologic impairment( n=22) and post-repair of esophageal atresia( n=1). Group III patients( n=6) were neurologically impaired but had no symptoms and underwent evaluation as a preoperative examination of gastrostomy placement. Reflux esophagitis was endoscopically graded according to the modified Los Angeles classification and grouped into grades?M, A, and?B. The results of GER studies and the histologic findings of reflux esophagitis were compared between these groups.Results:The parameters of 24-h pH monitoring were significantly higher in patients with grade?B than grade?M, and endoscopic grades improved after antireflux surgery along with the improvements in reflux index. There were no significant correlations between the endoscopic grade and the percentages of patients in whom histologic findings of reflux esophagitis were present.Conclusion:Esophageal endoscopy is useful for examining the severity of reflux esophagitis and monitoring the effect of treatment in children with GER/GERD. The modified Los Angeles classification can also be used for that purpose. Although treatment is seldom influenced by the results, histologic evaluation of the esophageal mucosa should be performed to exclude other disorders. | |||||||
| 書誌情報 |
Dokkyo journal of medical sciences 巻 41, 号 2, p. 155-165, 発行日 2014-07-25 |
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| ISSN | ||||||||
| 収録物識別子タイプ | ISSN | |||||||
| 収録物識別子 | 03855023 | |||||||
