| Item type |
[ELS]学術雑誌論文 / Journal Article(1) |
| 公開日 |
2017-05-24 |
| タイトル |
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タイトル |
Amantadine can Ameliorate Lower Urinary Tract Dysfunction and Nocturnal Polyuria in Patients with Parkinson Disease and Vascular Parkinsonism |
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言語 |
en |
| 言語 |
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言語 |
eng |
| キーワード |
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言語 |
en |
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主題 |
Amantadine |
| キーワード |
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言語 |
en |
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主題 |
Lower Urinary Tract Dysfunction |
| キーワード |
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言語 |
en |
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主題 |
Nocturnal Polyuria |
| キーワード |
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言語 |
en |
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主題 |
Parkinson's Disease |
| キーワード |
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言語 |
en |
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主題 |
Vascular Parkinsonism |
| 資源タイプ |
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資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
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資源タイプ |
journal article |
| 雑誌書誌ID |
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収録物識別子 |
AA00629581 |
| 論文名よみ |
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タイトル |
Amantadine can Ameliorate Lower Urinary Tract Dysfunction and Nocturnal Polyuria in Patients with Parkinson Disease and Vascular Parkinsonism |
| 著者 |
Tateno, Hiromi
Uchiyama, Tomoyuki
Yamamoto, Tatsuya
Watanabe, Yuka
Hashimoto, Kenichi
Shibata-yamaguchi, Chiharu
Fuse, Miki
Kamai, Takao
Yamanishi, Tomonori
Sakakibara, Ryuji
Kuwabara, Satoshi
Hirata, Koichi
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| 著者所属(英) |
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en |
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Department Of Neurology, Dokkyo Medical University |
| 著者所属(英) |
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en |
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Department Of Neurology, Dokkyo Medical University:Neurourology And Continence Center, Dokkyo Medical University:Department Of Neurology, Chiba University Graduate School Of Medicine |
| 著者所属(英) |
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en |
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Department Of Neurology, Chiba University Graduate School Of Medicine:Neurourology And Continence Center, Dokkyo Medical University:Department Of Neurology, Chiba University Graduate School Of Medicine |
| 著者所属(英) |
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en |
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Department Of Neurology, Dokkyo Medical University:Neurourology And Continence Center, Dokkyo Medical University:Department Of Neurology, Chiba University Graduate School Of Medicine |
| 著者所属(英) |
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en |
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Department Of Neurology, Dokkyo Medical University:Neurourology And Continence Center, Dokkyo Medical University:Department Of Neurology, Chiba University Graduate School Of Medicine |
| 著者所属(英) |
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en |
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Neurourology And Continence Center, Dokkyo Medical University:Neurourology And Continence Center, Dokkyo Medical University:Department Of Neurology, Chiba University Graduate School Of Medicine |
| 著者所属(英) |
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en |
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Neurourology And Continence Center, Dokkyo Medical University:Department Of Urology, Chiba University Graduate School Of Medicine:Department Of Neurology, Chiba University Graduate School Of Medicine |
| 著者所属(英) |
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en |
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Department Of Urology, Dokkyo Medical University:Department Of Urology, Chiba University Graduate School Of Medicine:Department Of Neurology, Chiba University Graduate School Of Medicine |
| 著者所属(英) |
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en |
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Neurourology And Continence Center, Dokkyo Medical University:Department Of Urology, Chiba University Graduate School Of Medicine:Department Of Neurology, Chiba University Graduate School Of Medicine |
| 著者所属(英) |
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en |
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Department Of Neurology, Chiba University Graduate School Of Medicine:Neurology Division, Department Of Internal Medicine, Sakura Medical Center, Toho University:Department Of Neurology, Chiba University Graduate School Of Medicine |
| 著者所属(英) |
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en |
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Department Of Neurology, Chiba University Graduate School Of Medicine:Neurology Division, Department Of Internal Medicine, Sakura Medical Center, Toho University:Department Of Neurology, Chiba University Graduate School Of Medicine |
| 著者所属(英) |
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en |
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Department Of Neurology, Dokkyo Medical University:Neurology Division, Department Of Internal Medicine, Sakura Medical Center, Toho University:Department Of Neurology, Chiba University Graduate School Of Medicine |
| 記事種別(英) |
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内容記述タイプ |
Other |
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内容記述 |
Original |
| 抄録(英) |
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内容記述タイプ |
Other |
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内容記述 |
Background:Amantadine is a drug used for patients with Parkinson's disease (PD) and vascular parkinsonism (VP). These patients often have lower urinary tract symptoms (LUTS) and nocturnal polyuria (NP). Thus, we investigated the effect of amantadine on these in parkinsonian patients.Methods:Twenty-two patients with LUTS, including 13 with PD and nine with VP, were recruited. We performed a urinary questionnaire, frequency-volume chart, and residual urine (RU) measurement before and after daily administration of 150 mg and 300 mg amantadine.Results:Before amantadine administration, mean daytime urinary frequency was 9.07(standard error [SE], 0.64), nighttime urinary frequency 2.89 (0.24), urinary urgency per week 24.2 (6.69), urge incontinence per month 15.1( 9.94), urine volume per void 145.6( 12.6) mL, and residual urine volume 12.5( 6.30) mL. After daily 150 mg amantadine administration, mean daytime and nighttime urinary frequency, urinary urgency, and urge incontinence decreased to 6.9( 0.42), 1.97( 0.21), 13.0( 3.58), and 14.2( 10.2), respectively, and urine volume per void increased to 174.1( 11.3) mL. NP( N=8) was ameliorated in six patients. No patient had side effects. After daily 300 mg amantadine administration( N=8), mean daytime and nighttimeurinary frequency, urinary urgency, and urge incontinence decreased to 6.90 (0.33), 1.69 (0.10), 5.88 (1.61), and 2.31 (0.61), respectively, and urine volume per void increased to180.2 (15.0) mL. NP (N=4) was ameliorated in two patients. One patient developed hallucination, and two patients developed flashing sensation.Conclusion:Amantadine has beneficial effects on LUTS and NP in patients with VP and PD. |
| 書誌情報 |
Dokkyo journal of medical sciences
巻 42,
号 1,
p. 21-29,
発行日 2015-03-25
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| ISSN |
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収録物識別子タイプ |
ISSN |
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収録物識別子 |
03855023 |
KJ00009786641.pdf (166.1 kB)
