ログイン
言語:

WEKO3

  • トップ
  • ランキング
To
lat lon distance
To

Field does not validate



インデックスリンク

インデックスツリー

メールアドレスを入力してください。

WEKO

One fine body…

WEKO

One fine body…

アイテム

{"_buckets": {"deposit": "0956d07b-36c8-4ddc-9622-bf7d77016a0e"}, "_deposit": {"created_by": 3, "id": "1266", "owners": [3], "pid": {"revision_id": 0, "type": "depid", "value": "1266"}, "status": "published"}, "_oai": {"id": "oai:dmu.repo.nii.ac.jp:00001266", "sets": ["74"]}, "author_link": ["6288", "6287", "6285", "6286", "6290", "6282", "6280", "6289", "6281", "6284", "6291", "6276", "6279", "6283", "6278", "6277"], "item_2_biblio_info_12": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2015-07-25", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "2", "bibliographicPageEnd": "87", "bibliographicPageStart": "83", "bibliographicVolumeNumber": "42", "bibliographic_titles": [{"bibliographic_title": "Dokkyo journal of medical sciences"}]}]}, "item_2_description_10": {"attribute_name": "抄録(日)", "attribute_value_mlt": [{"subitem_description": "確定診断前に凝固第VIII因子(F VIII)製剤の緊急投与を要した重症型血友病A の2 乳児例を報告する.症例1 は10 か月男児.反復する嘔吐を主訴に入院した.左上肢に腫張を伴う筋肉内出血と硬膜外血腫を認めた.症例2 は10 か月男児.止血困難な口唇裂傷後の出血を主訴に来院し,重度の貧血を認めた.2 例ともプロトロンビン時間(PT)正常,活性化プロトロンビン時間(APTT)の著明な延長より,血友病を強く疑った.いずれも重篤な出血を認めたため,凝固因子活性値による確定診断を待たず,緊急でF VIII製剤の投与を試みた.投与後2 例ともAPTT は改善し,出血症状も改善した.後日2 例ともにF VIII活性が1%未満と判明し,重症型血友病A と確定診断された.", "subitem_description_type": "Other"}]}, "item_2_description_11": {"attribute_name": "抄録(英)", "attribute_value_mlt": [{"subitem_description": "The cause of hemophilia A and B involves loss of factor VIII( FVIII) and factor IX( FIX), respectively. The hereditary form of this hemorrhagic disease is X-linked recessive. It is well established that the critical region for hemophilia A is localized on Xq28 and for hemophilia B on Xq27.1- 27.2. The initial symptom is bleeding in the mucous membranes often accompanied by intramuscular and intraarticular hemorrhage. The hemorrhages in the joints cause joint contracture as a sequela. The diagnosis of hemophilia is based on a normal bleeding and prothrombin time(PT)and prolonged activated partial thromboplastin time (APTT). We report here two infants of the severe typical from of hemophilia A who were treated with sufficient needed dosage of recombinant factor VIII before a final diagnosis was made. Case 1 was a 10-month-old boy. He was hospitalized for recurrent vomiting. He had intramuscular bleeding with swelling of the left shoulder and upper extremity. A head CT showed multiple epidural hematomas. Case 2 was a 10-month-old boy. He was sent to our hospital because of a lip laceration that did not stop bleeding, and he had severe anemia. We made the diagnosis of hemophilia A based on both their normal laboratory finding of PT and on the finding of extended APTT. Before confirming the decision diagnosis of hemophilia, we intravenously injected recombinant FVIII immediately, because of the severe hemorrhagic symptoms. After the therapy, both the APTT and hemorrhagic symptoms improved. These two cases were later confirmed as a severe infantile form of hemophilia A with less than 1 % factor VIII activity.", "subitem_description_type": "Other"}]}, "item_2_description_15": {"attribute_name": "表示順", "attribute_value_mlt": [{"subitem_description": "5", "subitem_description_type": "Other"}]}, "item_2_description_16": {"attribute_name": "アクセション番号", "attribute_value_mlt": [{"subitem_description": "KJ00009895942", "subitem_description_type": "Other"}]}, "item_2_description_8": {"attribute_name": "記事種別(日)", "attribute_value_mlt": [{"subitem_description": "症例報告", "subitem_description_type": "Other"}]}, "item_2_source_id_1": {"attribute_name": "雑誌書誌ID", "attribute_value_mlt": [{"subitem_source_identifier": "AA00629581", "subitem_source_identifier_type": "NCID"}]}, "item_2_source_id_19": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "03855023", "subitem_source_identifier_type": "ISSN"}]}, "item_2_text_6": {"attribute_name": "著者所属(日)", "attribute_value_mlt": [{"subitem_text_value": "獨協医科大学医学部 小児科学"}, {"subitem_text_value": "獨協医科大学医学部 小児科学"}, {"subitem_text_value": "獨協医科大学医学部 小児科学"}, {"subitem_text_value": "獨協医科大学医学部 小児科学"}, {"subitem_text_value": "獨協医科大学医学部 小児科学"}, {"subitem_text_value": "獨協医科大学医学部 小児科学"}, {"subitem_text_value": "獨協医科大学医学部 小児科学"}, {"subitem_text_value": "獨協医科大学医学部 小児科学"}]}, "item_2_text_7": {"attribute_name": "著者所属(英)", "attribute_value_mlt": [{"subitem_text_language": "en", "subitem_text_value": "Department Of Pediatrics, Dokkyo Medical University School Of Medicine"}, {"subitem_text_language": "en", "subitem_text_value": "Department Of Pediatrics, Dokkyo Medical University School Of Medicine"}, {"subitem_text_language": "en", "subitem_text_value": "Department Of Pediatrics, Dokkyo Medical University School Of Medicine"}, {"subitem_text_language": "en", "subitem_text_value": "Department Of Pediatrics, Dokkyo Medical University School Of Medicine"}, {"subitem_text_language": "en", "subitem_text_value": "Department Of Pediatrics, Dokkyo Medical University School Of Medicine"}, {"subitem_text_language": "en", "subitem_text_value": "Department Of Pediatrics, Dokkyo Medical University School Of Medicine"}, {"subitem_text_language": "en", "subitem_text_value": "Department Of Pediatrics, Dokkyo Medical University School Of Medicine"}, {"subitem_text_language": "en", "subitem_text_value": "Department Of Pediatrics, Dokkyo Medical University School Of Medicine"}]}, "item_2_title_3": {"attribute_name": "論文名よみ", "attribute_value_mlt": [{"subitem_title": "シンキ ケツユウビョウ A カンジャ ニ タイ スル ダイ 8 インシ セイザイ オ モチイ タ キンキュウ タイオウ : 2 ニュウジ レイ ホウコク"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "市川, 純子"}, {"creatorName": "イチカワ, ジユンコ", "creatorNameLang": "ja-Kana"}], "nameIdentifiers": [{"nameIdentifier": "6276", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "佐藤, 雄也"}, {"creatorName": "サトウ, ユウヤ", "creatorNameLang": "ja-Kana"}], "nameIdentifiers": [{"nameIdentifier": "6277", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "加納, 優治"}, {"creatorName": "カノウ, ユウジ", "creatorNameLang": "ja-Kana"}], "nameIdentifiers": [{"nameIdentifier": "6278", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "奥谷, 真由子"}, {"creatorName": "オクヤ, マユコ", "creatorNameLang": "ja-Kana"}], "nameIdentifiers": [{"nameIdentifier": "6279", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "今高, 城治"}, {"creatorName": "イマタカ, ジヨウジ", "creatorNameLang": "ja-Kana"}], "nameIdentifiers": [{"nameIdentifier": "6280", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "福島, 啓太郎"}, {"creatorName": "フクシマ, ケイタロウ", "creatorNameLang": "ja-Kana"}], "nameIdentifiers": [{"nameIdentifier": "6281", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "黒澤, 秀光"}, {"creatorName": "クロサワ, ヒデミツ", "creatorNameLang": "ja-Kana"}], "nameIdentifiers": [{"nameIdentifier": "6282", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "有阪, 治"}, {"creatorName": "アリサカ, オサム", "creatorNameLang": "ja-Kana"}], "nameIdentifiers": [{"nameIdentifier": "6283", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Ichikawa, Junko", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "6284", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Sato, Yuya", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "6285", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Kano, Yuji", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "6286", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Okuya, Mayuko", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "6287", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Imataka, George", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "6288", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Fukusima, Keitaro", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "6289", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Kurosawa, Hidemitsu", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "6290", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Arisaka, Osamu", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "6291", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2017-05-24"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "KJ00009895942.pdf", "filesize": [{"value": "306.4 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_free", "mimetype": "application/pdf", "size": 306400.0, "url": {"label": "KJ00009895942.pdf", "url": "https://dmu.repo.nii.ac.jp/record/1266/files/KJ00009895942.pdf"}, "version_id": "6ea177e1-7077-468b-9dc4-9db57a8376da"}]}, "item_keyword": {"attribute_name": "キーワード", "attribute_value_mlt": [{"subitem_subject": "重症型血友病A", "subitem_subject_scheme": "Other"}, {"subitem_subject": "凝固第VIII因子製剤", "subitem_subject_scheme": "Other"}, {"subitem_subject": "活性化部分トロンボプラスチン時間", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "jpn"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "journal article", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "新規血友病A 患者に対する第VIII因子製剤を用いた緊急対応 : 2 乳児例報告", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "新規血友病A 患者に対する第VIII因子製剤を用いた緊急対応 : 2 乳児例報告"}, {"subitem_title": "Emergency Medical Treatment with Recombinant Factor VIII for Hemostatic Control of Newly Diagnosed Hemophilia A:Two Infantile Case Reports", "subitem_title_language": "en"}]}, "item_type_id": "2", "owner": "3", "path": ["74"], "permalink_uri": "https://dmu.repo.nii.ac.jp/records/1266", "pubdate": {"attribute_name": "公開日", "attribute_value": "2017-05-24"}, "publish_date": "2017-05-24", "publish_status": "0", "recid": "1266", "relation": {}, "relation_version_is_last": true, "title": ["新規血友病A 患者に対する第VIII因子製剤を用いた緊急対応 : 2 乳児例報告"], "weko_shared_id": 3}
  1. Dokkyo Journal of Medical Sciences
  2. 42(2) 2015

新規血友病A 患者に対する第VIII因子製剤を用いた緊急対応 : 2 乳児例報告

https://dmu.repo.nii.ac.jp/records/1266
https://dmu.repo.nii.ac.jp/records/1266
b0eb2bf5-8e9c-4cb7-9d45-88eea07cd56d
名前 / ファイル ライセンス アクション
KJ00009895942.pdf KJ00009895942.pdf (306.4 kB)
Item type [ELS]学術雑誌論文 / Journal Article(1)
公開日 2017-05-24
タイトル
タイトル 新規血友病A 患者に対する第VIII因子製剤を用いた緊急対応 : 2 乳児例報告
タイトル
言語 en
タイトル Emergency Medical Treatment with Recombinant Factor VIII for Hemostatic Control of Newly Diagnosed Hemophilia A:Two Infantile Case Reports
言語
言語 jpn
キーワード
主題 重症型血友病A
キーワード
主題 凝固第VIII因子製剤
キーワード
主題 活性化部分トロンボプラスチン時間
資源タイプ
資源タイプ識別子 http://purl.org/coar/resource_type/c_6501
資源タイプ journal article
雑誌書誌ID
収録物識別子 AA00629581
論文名よみ
タイトル シンキ ケツユウビョウ A カンジャ ニ タイ スル ダイ 8 インシ セイザイ オ モチイ タ キンキュウ タイオウ : 2 ニュウジ レイ ホウコク
著者 市川, 純子

× 市川, 純子

WEKO 6276

市川, 純子

ja-Kana イチカワ, ジユンコ

Search repository
佐藤, 雄也

× 佐藤, 雄也

WEKO 6277

佐藤, 雄也

ja-Kana サトウ, ユウヤ

Search repository
加納, 優治

× 加納, 優治

WEKO 6278

加納, 優治

ja-Kana カノウ, ユウジ

Search repository
奥谷, 真由子

× 奥谷, 真由子

WEKO 6279

奥谷, 真由子

ja-Kana オクヤ, マユコ

Search repository
今高, 城治

× 今高, 城治

WEKO 6280

今高, 城治

ja-Kana イマタカ, ジヨウジ

Search repository
福島, 啓太郎

× 福島, 啓太郎

WEKO 6281

福島, 啓太郎

ja-Kana フクシマ, ケイタロウ

Search repository
黒澤, 秀光

× 黒澤, 秀光

WEKO 6282

黒澤, 秀光

ja-Kana クロサワ, ヒデミツ

Search repository
有阪, 治

× 有阪, 治

WEKO 6283

有阪, 治

ja-Kana アリサカ, オサム

Search repository
Ichikawa, Junko

× Ichikawa, Junko

WEKO 6284

en Ichikawa, Junko

Search repository
Sato, Yuya

× Sato, Yuya

WEKO 6285

en Sato, Yuya

Search repository
Kano, Yuji

× Kano, Yuji

WEKO 6286

en Kano, Yuji

Search repository
Okuya, Mayuko

× Okuya, Mayuko

WEKO 6287

en Okuya, Mayuko

Search repository
Imataka, George

× Imataka, George

WEKO 6288

en Imataka, George

Search repository
Fukusima, Keitaro

× Fukusima, Keitaro

WEKO 6289

en Fukusima, Keitaro

Search repository
Kurosawa, Hidemitsu

× Kurosawa, Hidemitsu

WEKO 6290

en Kurosawa, Hidemitsu

Search repository
Arisaka, Osamu

× Arisaka, Osamu

WEKO 6291

en Arisaka, Osamu

Search repository
著者所属(日)
獨協医科大学医学部 小児科学
著者所属(日)
獨協医科大学医学部 小児科学
著者所属(日)
獨協医科大学医学部 小児科学
著者所属(日)
獨協医科大学医学部 小児科学
著者所属(日)
獨協医科大学医学部 小児科学
著者所属(日)
獨協医科大学医学部 小児科学
著者所属(日)
獨協医科大学医学部 小児科学
著者所属(日)
獨協医科大学医学部 小児科学
著者所属(英)
en
Department Of Pediatrics, Dokkyo Medical University School Of Medicine
著者所属(英)
en
Department Of Pediatrics, Dokkyo Medical University School Of Medicine
著者所属(英)
en
Department Of Pediatrics, Dokkyo Medical University School Of Medicine
著者所属(英)
en
Department Of Pediatrics, Dokkyo Medical University School Of Medicine
著者所属(英)
en
Department Of Pediatrics, Dokkyo Medical University School Of Medicine
著者所属(英)
en
Department Of Pediatrics, Dokkyo Medical University School Of Medicine
著者所属(英)
en
Department Of Pediatrics, Dokkyo Medical University School Of Medicine
著者所属(英)
en
Department Of Pediatrics, Dokkyo Medical University School Of Medicine
記事種別(日)
内容記述タイプ Other
内容記述 症例報告
抄録(日)
内容記述タイプ Other
内容記述 確定診断前に凝固第VIII因子(F VIII)製剤の緊急投与を要した重症型血友病A の2 乳児例を報告する.症例1 は10 か月男児.反復する嘔吐を主訴に入院した.左上肢に腫張を伴う筋肉内出血と硬膜外血腫を認めた.症例2 は10 か月男児.止血困難な口唇裂傷後の出血を主訴に来院し,重度の貧血を認めた.2 例ともプロトロンビン時間(PT)正常,活性化プロトロンビン時間(APTT)の著明な延長より,血友病を強く疑った.いずれも重篤な出血を認めたため,凝固因子活性値による確定診断を待たず,緊急でF VIII製剤の投与を試みた.投与後2 例ともAPTT は改善し,出血症状も改善した.後日2 例ともにF VIII活性が1%未満と判明し,重症型血友病A と確定診断された.
抄録(英)
内容記述タイプ Other
内容記述 The cause of hemophilia A and B involves loss of factor VIII( FVIII) and factor IX( FIX), respectively. The hereditary form of this hemorrhagic disease is X-linked recessive. It is well established that the critical region for hemophilia A is localized on Xq28 and for hemophilia B on Xq27.1- 27.2. The initial symptom is bleeding in the mucous membranes often accompanied by intramuscular and intraarticular hemorrhage. The hemorrhages in the joints cause joint contracture as a sequela. The diagnosis of hemophilia is based on a normal bleeding and prothrombin time(PT)and prolonged activated partial thromboplastin time (APTT). We report here two infants of the severe typical from of hemophilia A who were treated with sufficient needed dosage of recombinant factor VIII before a final diagnosis was made. Case 1 was a 10-month-old boy. He was hospitalized for recurrent vomiting. He had intramuscular bleeding with swelling of the left shoulder and upper extremity. A head CT showed multiple epidural hematomas. Case 2 was a 10-month-old boy. He was sent to our hospital because of a lip laceration that did not stop bleeding, and he had severe anemia. We made the diagnosis of hemophilia A based on both their normal laboratory finding of PT and on the finding of extended APTT. Before confirming the decision diagnosis of hemophilia, we intravenously injected recombinant FVIII immediately, because of the severe hemorrhagic symptoms. After the therapy, both the APTT and hemorrhagic symptoms improved. These two cases were later confirmed as a severe infantile form of hemophilia A with less than 1 % factor VIII activity.
書誌情報 Dokkyo journal of medical sciences

巻 42, 号 2, p. 83-87, 発行日 2015-07-25
ISSN
収録物識別子 03855023
戻る
0
views
See details
Views

Versions

Ver.1 2023-06-20 16:01:20.771418
Show All versions

Share

Mendeley Twitter Facebook Print Addthis

Cite as

エクスポート

OAI-PMH
  • OAI-PMH JPCOAR
  • OAI-PMH DublinCore
  • OAI-PMH DDI
Other Formats
  • JSON
  • BIBTEX

Confirm


Powered by WEKO3


Powered by WEKO3