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Efficacy and Safety of Once-daily Oxybutynin Patch in Patients with Overactive Bladder Who had Experienced Adverse Reactions Caused by Oral Antimuscarinic Drugs
https://dmu.repo.nii.ac.jp/records/1472
https://dmu.repo.nii.ac.jp/records/14726da7dc9f-7eb6-40f6-b3ae-e0202aa32b87
名前 / ファイル | ライセンス | アクション |
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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タイトル | ||||||
タイトル | Efficacy and Safety of Once-daily Oxybutynin Patch in Patients with Overactive Bladder Who had Experienced Adverse Reactions Caused by Oral Antimuscarinic Drugs | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題 | overactive bladder | |||||
キーワード | ||||||
主題 | oxybutynin patch | |||||
キーワード | ||||||
主題 | application site erythema | |||||
キーワード | ||||||
主題 | adverse reactions | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
Yagi, Hiroshi
× Yagi, Hiroshi× Arai, Gaku× Soh, Shigehiro× Okada, Hiroshi |
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著者所属 | ||||||
Department of Urology, Dokkyo Medical University Koshigaya Hospital, Saitama, Japan | ||||||
著者所属 | ||||||
Department of Urology, Dokkyo Medical University Koshigaya Hospital, Saitama, Japan | ||||||
著者所属 | ||||||
Department of Urology, Dokkyo Medical University Koshigaya Hospital, Saitama, Japan | ||||||
書誌情報 |
Dokkyo Journal of Medical Sciences 巻 44, 号 1, p. 9-15, 発行日 2017-03-25 |
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要旨 | ||||||
内容記述タイプ | Other | |||||
内容記述 | Objectives:To evaluate the efficacy and safety of once-daily oxybutynin patch for overactive bladder (OAB) patients not tolerating oral antimuscarinic drugs. Methods:We prospectively investigated 43 OAB patients treated with once-daily oxybutynin patches for dry mouth and constipation due to oral antimuscarinic drugs. Results:Oxybutynin patch treatment for 8 weeks significantly improved the visual analogue scale scores for dry mouth and constipation;total score and subscore (mean number of urgency episodes and daily micturitions) for OAB symptoms;and King’s Health Questionnaire scores for social limitations, emotions and sleep/energy (P=0.016 and 0.001;0.008, 0.041 and 0.015;and 0.007, 0.003 and 0.026, respectively). The 3-day frequency volume chart showed significant improvement in hours of undisturbed sleep(P=0.011). Eight patients had adverse reactions at the application site and withdrew from the study, while others only developed mild erythema and pruritus. Conclusions:Oxybutynin patch reduces adverse reactions caused by oral antimuscarinic drugs. |
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記事種別 | ||||||
Original | ||||||
出版者 | ||||||
出版者 | 獨協医学会 | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 03855023 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AA00629581 | |||||
表示順 | ||||||
3 |