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Generalized Discoid Lupus Erythematosus with Systemic Lupus Erythematosus: A Therapeutic Challenge
https://dmu.repo.nii.ac.jp/records/2000051
https://dmu.repo.nii.ac.jp/records/200005198f9403b-3a7c-4930-98f0-5e34074c5223
| 名前 / ファイル | ライセンス | アクション |
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DKMJ-2-1-11.pdf (1.3 MB)
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||||||||||
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| タイトル | ||||||||||||||
| タイトル | Generalized Discoid Lupus Erythematosus with Systemic Lupus Erythematosus: A Therapeutic Challenge | |||||||||||||
| 言語 | en | |||||||||||||
| 言語 | ||||||||||||||
| 言語 | eng | |||||||||||||
| キーワード | ||||||||||||||
| 言語 | en | |||||||||||||
| 主題Scheme | Other | |||||||||||||
| 主題 | combination therapy | |||||||||||||
| キーワード | ||||||||||||||
| 言語 | en | |||||||||||||
| 主題Scheme | Other | |||||||||||||
| 主題 | generalized discoid lupus erythematosus | |||||||||||||
| キーワード | ||||||||||||||
| 言語 | en | |||||||||||||
| 主題Scheme | Other | |||||||||||||
| 主題 | prognosis | |||||||||||||
| キーワード | ||||||||||||||
| 言語 | en | |||||||||||||
| 主題Scheme | Other | |||||||||||||
| 主題 | systemic lupus erythematosus | |||||||||||||
| 資源タイプ | ||||||||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||||||||
| 資源タイプ | journal article | |||||||||||||
| 著者 |
Suryawati, Nyoman
× Suryawati, Nyoman
× Puspawati, Ni Made Dwi
× Nukana, Ratih Purnamasari
× Saputra, Herman
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| 書誌情報 |
en : Dokkyo Medical Journal 巻 2, 号 2, p. 175-181, 発行日 2023-06-25 |
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| 内容記述 | ||||||||||||||
| 内容記述タイプ | Abstract | |||||||||||||
| 内容記述 | Introduction: Generalized discoid lupus erythematosus (DLE) is a rare skin manifestation; however, about 15-28% of cases may develop into Systemic Lupus Erythematosus (SLE). Generalized DLE with SLE showed a poorer prognosis and required holistic therapy. Case Report: A 20-year-old female complained of red rash on the skin, worsen with sun exposure in the past two years. She complained of joint pain, fever, decreased appetite, and fatigue, twenty months after the skin rash onset. Skin examination on the scalp, face, trunk, hands and feet showed erythematous to hypopigmentation patches, atrophic skin, and erosions covered with crusts. Laboratory investigations revealed anemia, high titers of ANA, and anti-dsDNA. Histopathological results were consistent with lupus erythematosus. Consultation with an ophthalmologist showed no contraindications to hydroxychloroquine. She was diagnosed with generalized DLE with moderate SLE and showed an excellent response to hydroxychloroquine, methotrexate, both systemic and topical corticosteroids, and sunscreen. Discussion: Generalized cutaneous lupus can be treated with a topical therapy such as corticosteroid, sunscreen, and systemic therapy such as hydroxychloroquine and corticosteroid. Methotrexate, as a steroid-sparing agent, has a role in treating moderate to severe SLE and lupus arthritis. Conclusion: Early recognition of SLE in a patient with cutaneous lupus and adequate therapy in generalized DLE is essential. Combination therapy showed better efficacy than monotherapy in generalized cutaneous lupus accompanied by SLE. |
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| 言語 | en | |||||||||||||
| 出版者 | ||||||||||||||
| 出版者 | Dokkyo Medical Society | |||||||||||||
| ISSN | ||||||||||||||
| 収録物識別子タイプ | EISSN | |||||||||||||
| 収録物識別子 | 2436-522X | |||||||||||||
| 書誌レコードID | ||||||||||||||
| 収録物識別子タイプ | NCID | |||||||||||||
| 収録物識別子 | AA12941861 | |||||||||||||
| DOI | ||||||||||||||
| 関連タイプ | isIdenticalTo | |||||||||||||
| 識別子タイプ | DOI | |||||||||||||
| 関連識別子 | https://doi.org/10.51040/dkmj.2022-063 | |||||||||||||
| 出版タイプ | ||||||||||||||
| 出版タイプ | VoR | |||||||||||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||||||||||
