Item type |
学術雑誌論文 / Journal Article(1) |
タイトル |
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タイトル |
Differences in Intraocular Lens Surface Properties and Lens Epithelial Cell Behavior |
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言語 |
en |
言語 |
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言語 |
eng |
キーワード |
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言語 |
en |
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主題Scheme |
Other |
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主題 |
cell behavior |
キーワード |
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言語 |
en |
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主題Scheme |
Other |
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主題 |
cell culture |
キーワード |
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言語 |
en |
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主題Scheme |
Other |
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主題 |
lens epithelial cells |
キーワード |
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言語 |
en |
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主題Scheme |
Other |
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主題 |
secondary cataract |
キーワード |
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言語 |
en |
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主題Scheme |
Other |
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主題 |
secondary cataract |
キーワード |
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言語 |
en |
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主題Scheme |
Other |
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主題 |
surface modification |
資源タイプ |
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資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
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資源タイプ |
journal article |
アクセス権 |
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アクセス権 |
open access |
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アクセス権URI |
http://purl.org/coar/access_right/c_abf2 |
著者 |
Okayasu, Akihiko
Mukai, Koichiro
Matsushima, Hiroyuki
Nagata, Mayumi
Senoo, Tadashi
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書誌情報 |
en : Dokkyo Medical Journal
巻 2,
号 4,
p. 289-294,
発行日 2023-12-25
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記事種別 |
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Original |
内容記述 |
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内容記述タイプ |
Abstract |
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内容記述 |
Posterior capsule opacification is a common complication following cataract surgery. However, its incidence varies depending on the type of intraocular lens (IOL) used. In this study, we analyzed the adhesion and movement of lens epithelial cells (LECs) in the early stages after cataract surgery by continuously observing LECs seeded on the surfaces of different types of IOLs. PY-60AD and XY1 hydrophobic acrylic IOLs were used. Each posterior surface was modified to increase the adhesion. The IOLs were placed in culture dishes with an exposed posterior or anterior surface (three each). LECs extracted from white rabbit lenses by trypsinization were seeded onto IOLs. LEC movement and shape were recorded by microscopy using a cell culture observation system after 6 h of contact between LECs and IOLs. The cumulative distance traveled was calculated from the LEC trajectories after comparing the shapes of the LECs. We observed that LECs were more likely to adhere to XY1 modified posterior surface. The speed of LEC movement decreased after adhesion. These findings support the conclusion that increasing the adhesiveness of IOL surfaces inhibits the LEC movement. |
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言語 |
en |
出版者 |
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出版者 |
Dokkyo Medical Society |
ISSN |
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収録物識別子タイプ |
EISSN |
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収録物識別子 |
2436-522X |
書誌レコードID |
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収録物識別子タイプ |
NCID |
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収録物識別子 |
AA12941861 |
DOI |
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関連タイプ |
isIdenticalTo |
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識別子タイプ |
DOI |
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関連識別子 |
https://doi.org/10.51040/dkmj.2023-010 |
出版タイプ |
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出版タイプ |
VoR |
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出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |