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  1. Dokkyo Medical Journal
  2. 3(2) 2024

Respiratory Arrest due to Muscle Paralysis Caused by Mono, Bis- (Trimethylammoniummethylene Chloride) -Alkyl-Toluene Injection: A Case Report

https://dmu.repo.nii.ac.jp/records/2000359
https://dmu.repo.nii.ac.jp/records/2000359
5484eafa-6645-481d-b2d3-cf670576031a
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DKMJ-3-2-11.pdf DKMJ-3-2-11.pdf (259 KB)
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Item type 学術雑誌論文 / Journal Article(1)
タイトル
タイトル Respiratory Arrest due to Muscle Paralysis Caused by Mono, Bis- (Trimethylammoniummethylene Chloride) -Alkyl-Toluene Injection: A Case Report
言語 en
言語
言語 eng
キーワード
言語 en
主題Scheme Other
主題 Quaternary ammonium compounds,,
キーワード
言語 en
主題Scheme Other
主題 respiratory muscle paralysis
キーワード
言語 en
主題Scheme Other
主題 TAMCA
資源タイプ
資源タイプ識別子 http://purl.org/coar/resource_type/c_6501
資源タイプ journal article
アクセス権
アクセス権 open access
アクセス権URI http://purl.org/coar/access_right/c_abf2
著者 Honda, Arata

× Honda, Arata

en Honda, Arata

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Hayashi, Kentaro

× Hayashi, Kentaro

en Hayashi, Kentaro

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Hayashi, Kenji

× Hayashi, Kenji

en Hayashi, Kenji

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Wake, Koji

× Wake, Koji

ja Wake, Koji

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書誌情報 Dokkyo Medical Journal

巻 3, 号 2, p. 158-161, 発行日 2024-06-25
記事種別
値 Case Report
内容記述
内容記述タイプ Abstract
内容記述 Quaternary ammonium compounds are a large class of permanently charged cationic chemicals used in various consumer and industrial products owing to their antimicrobial properties; mono, bis- (trimethylammoniummethylene chloride) -alkyl-toluene (TAMCA) exhibits bactericidal activity by denaturing the proteins in the bacterial membrane when the cations in its structure are adsorbed to the anionic structure on the bacterial surface. Here, we report the first case of respiratory arrest due to muscle paralysis caused by subcutaneous injection of TAMCA. A 26-year-old man accidently injected with the aforementioned compound, developed respiratory arrest after approximately 1 h. We diagnosed him with TAMCA-related toxicosis. We successfully treated him by ventilatory management followed by tracheal intubation by injecting 10 mL of 1% propofol (100 mg), as he resumed spontaneous breathing the next day, about 15 h following the incident. Subsequently, he developed necrotizing soft tissue and underwent debridement and skin grafting surgery. This case demonstrated that TAMCA erroneous subcutaneous injection or administration into the human body may induce respiratory muscle paralysis thereby necessitating prompt treatment.
言語 en
出版者
出版者 Dokkyo Medical Society
ISSN
収録物識別子タイプ EISSN
収録物識別子 2436-522X
書誌レコードID
収録物識別子タイプ NCID
収録物識別子 AA12941861
出版タイプ
出版タイプ VoR
出版タイプResource http://purl.org/coar/version/c_970fb48d4fbd8a85
他の資源との関係
関連タイプ isIdenticalTo
識別子タイプ DOI
関連識別子 https://doi.org/10.51040/dkmj.2023-042
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