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Corneal Perforation Associated with the Oral Anticancer Drug S-1：A Case Report
https://dmu.repo.nii.ac.jp/records/2295
https://dmu.repo.nii.ac.jp/records/2295a77883f4-0f02-4b8f-85eb-a0e9202cb120
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
DJMS-47-1-Muto-本文 (63.0 kB)
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| タイトル | ||||||
| タイトル | Corneal Perforation Associated with the Oral Anticancer Drug S-1：A Case Report | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | S-1 | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | corneal perforation | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | ocular complication | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | 5-FU | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| 著者 |
Muto, Tetsuya
× Muto, Tetsuya× Machida, Shigeki |
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| 著者所属 | ||||||
| 値 | Department of Ophthalmology, Dokkyo Medical University Saitama Medical Center, Koshigaya, Japan | |||||
| 著者所属 | ||||||
| 値 | Department of Ophthalmology, Dokkyo Medical University Saitama Medical Center, Koshigaya, Japan | |||||
| 書誌情報 |
Dokkyo Journal of Medical Sciences 巻 47, 号 1, p. 35-37, 発行日 2020-03-25 |
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| 要旨 | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | Purpose：S-1 is an oral anticancer drug containing tegafur, a prodrug of 5-fluorouracil（5-FU）. We present a patient who experienced corneal perforation that appeared to be caused by S-1 administration． Case：A 67-year-old woman was presented to our hospital because of corneal perforation in her left eye. She had been administrated S-1 for 17 months from gastroenterological surgeon at another hospital for treating pancreatic cancer. The best-corrected visual acuity was 0.4 in the right eye and 0.1 in the left eye at the initial visit. Convoluted subepithelial opacity was present in the cornea of the right eye, and corneal perforation was observed in the left eye. Anterior chamber formation was very poor, and iris incarceration was present in the left eye. Although anterior chamber formation was attempted with the use of soft contact lens wear, the condition remained unchanged. We requested to discontinue S-1 administration to gastroenterological surgery at another hospital. The patient was presented to the department of ophthalmology at another hospital because her eye condition and pancreatic cancer could be treated at the same institution. Conclusion：Patients treated with S-1 should be carefully followed up for ocular complications because corneal perforation may occur. |
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| 記事種別 | ||||||
| 値 | Case Report | |||||
| 出版者 | ||||||
| 出版者 | 獨協医学会 | |||||
| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 03855023 | |||||
| 書誌レコードID | ||||||
| 収録物識別子タイプ | NCID | |||||
| 収録物識別子 | AA00629581 | |||||
