Item type |
[ELS]学術雑誌論文 / Journal Article(1) |
公開日 |
2017-05-24 |
タイトル |
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タイトル |
Hemodynamic Effects of Positive end-expiratory Pressure on Right Ventricular Diastolic Function in Patients with Acute Myocardial Infarction |
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言語 |
en |
言語 |
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言語 |
eng |
キーワード |
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言語 |
en |
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主題 |
diastole |
キーワード |
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言語 |
en |
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主題 |
congestive heart failure |
キーワード |
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言語 |
en |
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主題 |
right ventricle |
キーワード |
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言語 |
en |
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主題 |
PEEP |
資源タイプ |
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資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
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資源タイプ |
journal article |
雑誌書誌ID |
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収録物識別子 |
AA00629581 |
論文名よみ |
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タイトル |
Hemodynamic Effects of Positive end-expiratory Pressure on Right Ventricular Diastolic Function in Patients with Acute Myocardial Infarction |
著者 |
Kuga, Hideyo
Nakamoto, Takaaki
Harasawa, Hiroshi
Taguchi, Isao
Fuse, Daisuke
Abe, Shichiro
Susuki, Hidehiko
Hoshi, Toshiyasu
Horie, Yasuto
Sugimura, Hiroyuki
Amano, Hiroshi
Kaneko, Noboru
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著者所属(英) |
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en |
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Department of Cardiology and Pneumology, Dokkyo University School of Medicine |
著者所属(英) |
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en |
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Department of Cardiology and Pneumology, Dokkyo University School of Medicine |
著者所属(英) |
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en |
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Department of Cardiology and Pneumology, Dokkyo University School of Medicine |
著者所属(英) |
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en |
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Department of Cardiology and Pneumology, Dokkyo University School of Medicine |
著者所属(英) |
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en |
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Department of Cardiology and Pneumology, Dokkyo University School of Medicine |
著者所属(英) |
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en |
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Department of Cardiology and Pneumology, Dokkyo University School of Medicine |
著者所属(英) |
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en |
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Department of Cardiology and Pneumology, Dokkyo University School of Medicine |
著者所属(英) |
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en |
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Department of Cardiology and Pneumology, Dokkyo University School of Medicine |
著者所属(英) |
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en |
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Department of Cardiology and Pneumology, Dokkyo University School of Medicine |
著者所属(英) |
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en |
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Department of Cardiology and Pneumology, Dokkyo University School of Medicine |
著者所属(英) |
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en |
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Department of Cardiology and Pneumology, Dokkyo University School of Medicine |
著者所属(英) |
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en |
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Department of Cardiology and Pneumology, Dokkyo University School of Medicine |
記事種別(日) |
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内容記述タイプ |
Other |
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内容記述 |
原著 |
記事種別(英) |
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内容記述タイプ |
Other |
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内容記述 |
Original |
抄録(英) |
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内容記述タイプ |
Other |
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内容記述 |
The effects of positive end-expiratory pressure (PEEP) on the right ventricular (RV) diastolic function in patients with congestive heart failure (CHF) due to acute myocardial infarction (AMI) are unknown. The aim in this study was to investigate PEEP associated variations in RV diastolic function in CHF due to AMI. The subjects comprised the control group (26 subjects) and the AMI group (36 subjects) classified as 20 patients with pulmonary capillary wedge pressure (PCWP) < 18 mmHg (CHF-low PCWP group) and 16 patients with PCWP≧18mmHg (CHF-high PCWP group). PEEP was applied for 30 minutes at 0, 5, 10 and 15 cmH_20. Two-dimensional echocardiography with continuous and pulse wave Doppler studies was performed. RV diastolic functional parameters included the ratio of peak early tricuspid valve filling and peak atrial filling velocities, the decelation time of the tricuspid E valve and the RV isovolumic relaxation time. In the control and CHF-low PCWP groups, right atrial pressure, mean pulmonary arterial pressure (mPAP), total pulmonary resistance (TPR) and systemic vascular resistance (SVR) increased, output (CO) decreased and RV diastolic functional parameters worsened significantly at the transition from 10 to 15 cmH_20 PEEP. In the CHF-high PCWP group, mPAP, TPR and SVR decreased, while CO increased and RV diastolic functional parameters improved significantly at the transition from 10 to 15 cmH_20 PEEP. From these findings, it is clear that PEEP induced hemodynamic deterioration and reduces RV diastolic function in intact and mildly failing hearts. On the other hand, in severely failing hearts, PEEP effers hemodynamic improvement and ameliorates RV diastolic function. It appears possible to predict responses to PEEP by determining RV diastolic function in CHF. Therefore, we conclude that evaluation of the RV diastolic function during PEEP is highly important in terms of recognizing the effectiveness of PEEP therapy in CHF. |
書誌情報 |
Dokkyo journal of medical sciences
巻 31,
号 2,
p. 99-108,
発行日 2004-07-25
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ISSN |
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収録物識別子タイプ |
ISSN |
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収録物識別子 |
03855023 |