{"_buckets": {"deposit": "a0f2afe9-82d0-4787-b957-8738c5029fe4"}, "_deposit": {"created_by": 3, "id": "420", "owners": [3], "pid": {"revision_id": 0, "type": "depid", "value": "420"}, "status": "published"}, "_oai": {"id": "oai:dmu.repo.nii.ac.jp:00000420", "sets": ["37"]}, "author_link": ["1686", "1685"], "item_2_biblio_info_12": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2006-03-25", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "1", "bibliographicPageEnd": "34", "bibliographicPageStart": "25", "bibliographicVolumeNumber": "33", "bibliographic_titles": [{"bibliographic_title": "Dokkyo journal of medical sciences"}]}]}, "item_2_description_11": {"attribute_name": "抄録(英)", "attribute_value_mlt": [{"subitem_description": "Angiogenesis is a key process in tumor growth and metastasis. In 27 patients with advanced gastric carcinoma before operation and 9 healthy controls, plasma levels of endostatin (ES), cathepsin L (Cat-L) and soluble VEGF R1/Flt-1 (sVEGF R1), which are known to suppress angiogenesis, tumor growth and metastasis, were measured by ELISA in order to examine the clinical importance of the agents. In addition, expression of CD34, ES and Cat-L in tissues of the gastric carcinoma was investigated immunohistochemically in order to elucidate the correlation with the above plasma levels. Plasma ES levels in gastric carcinoma patients were significantly higher than those in controls (p=0.001). Plasma Cat-L levels in controls were slightly lower, though not significantly (p=0.065), than those in carcinoma patients. There was no significant difference in sVEGF R1 levels between gastric carcinoma patients and controls. Expression of ES and Cat-L in tumor tissues was positively associated with plasma sVEGF R1 levels. Expression of CD34 in tumor tissues was not found to be associated with any plasma markers. Our results suggested that plasma ES levels are elevated in gastric carcinoma and may be useful markers for gastric carcinoma.", "subitem_description_type": "Other"}]}, "item_2_description_15": {"attribute_name": "表示順", "attribute_value_mlt": [{"subitem_description": "6", "subitem_description_type": "Other"}]}, "item_2_description_16": {"attribute_name": "アクセション番号", "attribute_value_mlt": [{"subitem_description": "KJ00004451269", "subitem_description_type": "Other"}]}, "item_2_description_8": {"attribute_name": "記事種別(日)", "attribute_value_mlt": [{"subitem_description": "原著", "subitem_description_type": "Other"}]}, "item_2_description_9": {"attribute_name": "記事種別(英)", "attribute_value_mlt": [{"subitem_description": "Original", "subitem_description_type": "Other"}]}, "item_2_source_id_1": {"attribute_name": "雑誌書誌ID", "attribute_value_mlt": [{"subitem_source_identifier": "AA00629581", "subitem_source_identifier_type": "NCID"}]}, "item_2_source_id_19": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "03855023", "subitem_source_identifier_type": "ISSN"}]}, "item_2_text_7": {"attribute_name": "著者所属(英)", "attribute_value_mlt": [{"subitem_text_language": "en", "subitem_text_value": "First Department of Surgery, Dokkyo University School of Medicine"}, {"subitem_text_language": "en", "subitem_text_value": "First Department of Surgery, Dokkyo University School of Medicine"}]}, "item_2_title_3": {"attribute_name": "論文名よみ", "attribute_value_mlt": [{"subitem_title": "Plasma Endostatin Levels are Elevated in Patients with Gastric Carcinoma"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Ohkawa, Tetsuya", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "1685", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Miyachi, Kazuhito", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "1686", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2017-05-24"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "KJ00004451269.pdf", "filesize": [{"value": "2.4 MB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_free", "mimetype": "application/pdf", "size": 2400000.0, "url": {"label": "KJ00004451269.pdf", "url": "https://dmu.repo.nii.ac.jp/record/420/files/KJ00004451269.pdf"}, "version_id": "8a671df1-0219-415b-89e2-643793825db2"}]}, "item_keyword": {"attribute_name": "キーワード", "attribute_value_mlt": [{"subitem_subject": "Angiogenesis", "subitem_subject_language": "en", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Endostatin", "subitem_subject_language": "en", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Cathepsin L", "subitem_subject_language": "en", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Soluble VEGF R1/Flt-1", "subitem_subject_language": "en", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "journal article", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "Plasma Endostatin Levels are Elevated in Patients with Gastric Carcinoma", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "Plasma Endostatin Levels are Elevated in Patients with Gastric Carcinoma", "subitem_title_language": "en"}]}, "item_type_id": "2", "owner": "3", "path": ["37"], "permalink_uri": "https://dmu.repo.nii.ac.jp/records/420", "pubdate": {"attribute_name": "公開日", "attribute_value": "2017-05-24"}, "publish_date": "2017-05-24", "publish_status": "0", "recid": "420", "relation": {}, "relation_version_is_last": true, "title": ["Plasma Endostatin Levels are Elevated in Patients with Gastric Carcinoma"], "weko_shared_id": 3}